Hepatocellular adenoma causes: Difference between revisions

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{{Hepatocellular adenoma}}
{{Hepatocellular adenoma}}


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==Overview==
[[Estrogen]] has a central role in the development of hepatocellular adenoma. The [[Causality|causes]] of hepatocellular adenoma can include the settings where prolonged and/or excessive [[estrogen]] exposure is involved. These can include [[Oral contraceptive|oral contraceptive medications]], [[pregnancy]], long term use of [[anabolic]] [[Androgen|androgenic]] [[Steroid|steroids]], [[metabolic syndrome]], [[obesity]], [[Glycogen storage disease|glycogen storage diseases]], and [[clomiphene]].
 
==Causes==
 
* [[Estrogen]] has a central role in the development of hepatocellular adenoma.
* The [[Causality|causes]] of hepatocellular adenoma can include the settings involving prolonged and/or excessive [[estrogen]] exposure, such as:<ref>{{Cite journal
| author = [[M. Kawakatsu]], [[V. Vilgrain]], [[S. Erlinger]] & [[H. Nahum]]
| title = Disappearance of liver cell adenoma: CT and MR imaging
| journal = [[Abdominal imaging]]
| volume = 22
| issue = 3
| pages = 274–276
| year = 1997
| month = May-June
| pmid = 9107649
}}</ref><ref>{{Cite journal
| author = [[W. H. Marks]], [[N. Thompson]] & [[H. Appleman]]
| title = Failure of hepatic adenomas (HCA) to regress after discontinuance of oral contraceptives. An association with focal nodular hyperplasia (FNH) and uterine leiomyoma
| journal = [[Annals of surgery]]
| volume = 208
| issue = 2
| pages = 190–195
| year = 1988
| month = August
| pmid = 2840865
}}</ref<nowiki><ref></nowiki>{{Cite journal
| author = [[H. Tesluk]] & [[J. Lawrie]]
| title = Hepatocellular adenoma. Its transformation to carcinoma in a user of oral contraceptives
| journal = [[Archives of pathology & laboratory medicine]]
| volume = 105
| issue = 6
| pages = 296–299
| year = 1981
| month = June
| pmid = 6263214
}}</ref><ref>{{Cite journal
| author = [[D. Carrasco]], [[M. Barrachina]], [[M. Prieto]] & [[J. Berenguer]]
| title = Clomiphene citrate and liver-cell adenoma
| journal = [[The New England journal of medicine]]
| volume = 310
| issue = 17
| pages = 1120–1121
| year = 1984
| month = April
| doi = 10.1056/NEJM198404263101716
| pmid = 6323982
}}</ref><ref>{{Cite journal
| author = [[G. B. Coombes]], [[J. Reiser]], [[F. J. Paradinas]] & [[I. Burn]]
| title = An androgen-associated hepatic adenoma in a trans-sexual
| journal = [[The British journal of surgery]]
| volume = 65
| issue = 12
| pages = 869–870
| year = 1978
| month = December
| pmid = 737424
}}</ref><ref>{{Cite journal
| author = [[U. Beuers]], [[W. O. Richter]], [[M. M. Ritter]], [[B. Wiebecke]] & [[P. Schwandt]]
  | title = Klinefelter's syndrome and liver adenoma
| journal = [[Journal of clinical gastroenterology]]
| volume = 13
| issue = 2
| pages = 214–216
| year = 1991
| month = April
| pmid = 1851773
}}</ref><ref>{{Cite journal
| author = [[N. S. Alshak]], [[J. Cocjin]], [[L. Podesta]], [[R. van de Velde]], [[L. Makowka]], [[P. Rosenthal]] & [[S. A. Geller]]
| title = Hepatocellular adenoma in glycogen storage disease type IV
| journal = [[Archives of pathology & laboratory medicine]]
| volume = 118
| issue = 1
| pages = 88–91
| year = 1994
| month = January
| pmid = 8285839
}}</ref><ref>{{Cite journal
| author = [[P. Labrune]], [[P. Trioche]], [[I. Duvaltier]], [[P. Chevalier]] & [[M. Odievre]]
| title = Hepatocellular adenomas in glycogen storage disease type I and III: a series of 43 patients and review of the literature
| journal = [[Journal of pediatric gastroenterology and nutrition]]
| volume = 24
| issue = 3
  | pages = 276–279
  | year = 1997
| month = March
| pmid = 9138172
}}</ref><ref>{{Cite journal
| author = [[S. Bala]], [[P. H. Wunsch]] & [[W. G. Ballhausen]]
| title = Childhood hepatocellular adenoma in familial adenomatous polyposis: mutations in adenomatous polyposis coli gene and p53
| journal = [[Gastroenterology]]
  | volume = 112
| issue = 3
| pages = 919–922
| year = 1997
| month = March
| pmid = 9041254
}}</ref><ref>{{Cite journal
| author = [[J. K. Baum]], [[J. J. Bookstein]], [[F. Holtz]] & [[E. W. Klein]]
| title = Possible association between benign hepatomas and oral contraceptives
| journal = [[Lancet (London, England)]]
| volume = 2
| issue = 7835
| pages = 926–929
| year = 1973
| month = October
| pmid = 4126557
}}</ref>
 
:*[[Oral contraceptive|Oral contraceptive medications]]
:*[[Pregnancy]]
:*[[Glycogen storage disease type I|Glycogen storage disease types I]],[[Glycogen storage disease type II|II]] and [[Glycogen storage disease type IV|IV]]
:*Long term use of [[anabolic]] [[Androgen|androgenic]] [[Steroid|steroids]]
:*[[Metabolic syndrome]]
:*[[Obesity]]
:*[[Clomiphene]]


==References==
==References==
{{reflist|2}}
{{reflist|1}}


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Latest revision as of 18:24, 20 August 2019

Hepatocellular adenoma Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]

Overview

Estrogen has a central role in the development of hepatocellular adenoma. The causes of hepatocellular adenoma can include the settings where prolonged and/or excessive estrogen exposure is involved. These can include oral contraceptive medications, pregnancy, long term use of anabolic androgenic steroids, metabolic syndrome, obesity, glycogen storage diseases, and clomiphene.

Causes

References

  1. ↑ M. Kawakatsu, V. Vilgrain, S. Erlinger & H. Nahum (1997). "Disappearance of liver cell adenoma: CT and MR imaging". Abdominal imaging. 22 (3): 274–276. PMID 9107649. Unknown parameter |month= ignored (help)
  2. ↑ W. H. Marks, N. Thompson & H. Appleman (1988). "Failure of hepatic adenomas (HCA) to regress after discontinuance of oral contraceptives. An association with focal nodular hyperplasia (FNH) and uterine leiomyoma". Annals of surgery. 208 (2): 190–195. PMID 2840865. Unknown parameter |month= ignored (help)</ref<ref>H. Tesluk & J. Lawrie (1981). "Hepatocellular adenoma. Its transformation to carcinoma in a user of oral contraceptives". Archives of pathology & laboratory medicine. 105 (6): 296–299. PMID 6263214. Unknown parameter |month= ignored (help)
  3. ↑ D. Carrasco, M. Barrachina, M. Prieto & J. Berenguer (1984). "Clomiphene citrate and liver-cell adenoma". The New England journal of medicine. 310 (17): 1120–1121. doi:10.1056/NEJM198404263101716. PMID 6323982. Unknown parameter |month= ignored (help)
  4. ↑ G. B. Coombes, J. Reiser, F. J. Paradinas & I. Burn (1978). "An androgen-associated hepatic adenoma in a trans-sexual". The British journal of surgery. 65 (12): 869–870. PMID 737424. Unknown parameter |month= ignored (help)
  5. ↑ U. Beuers, W. O. Richter, M. M. Ritter, B. Wiebecke & P. Schwandt (1991). "Klinefelter's syndrome and liver adenoma". Journal of clinical gastroenterology. 13 (2): 214–216. PMID 1851773. Unknown parameter |month= ignored (help)
  6. ↑ N. S. Alshak, J. Cocjin, L. Podesta, R. van de Velde, L. Makowka, P. Rosenthal & S. A. Geller (1994). "Hepatocellular adenoma in glycogen storage disease type IV". Archives of pathology & laboratory medicine. 118 (1): 88–91. PMID 8285839. Unknown parameter |month= ignored (help)
  7. ↑ P. Labrune, P. Trioche, I. Duvaltier, P. Chevalier & M. Odievre (1997). "Hepatocellular adenomas in glycogen storage disease type I and III: a series of 43 patients and review of the literature". Journal of pediatric gastroenterology and nutrition. 24 (3): 276–279. PMID 9138172. Unknown parameter |month= ignored (help)
  8. ↑ S. Bala, P. H. Wunsch & W. G. Ballhausen (1997). "Childhood hepatocellular adenoma in familial adenomatous polyposis: mutations in adenomatous polyposis coli gene and p53". Gastroenterology. 112 (3): 919–922. PMID 9041254. Unknown parameter |month= ignored (help)
  9. ↑ J. K. Baum, J. J. Bookstein, F. Holtz & E. W. Klein (1973). "Possible association between benign hepatomas and oral contraceptives". Lancet (London, England). 2 (7835): 926–929. PMID 4126557. Unknown parameter |month= ignored (help)


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