Hepatocellular adenoma CT: Difference between revisions

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{{Hepatocellular adenoma}}
{{Hepatocellular adenoma}}
{{CMG}}; {{AOEIC}} {{CZ}}
{{CMG}}; {{AOEIC}} {{CZ}}{{Sab}}


==Overview==
==Overview==
The CT scan appearances of hepatocellular adenoma are usually variable and characteristic lesions are best seen with multiphase helical CT scanning. The CT scan findings include; nonlobulated well marginated mass that can be encapsulated and is rarely calcified, heterogeneous hypoattenuating area within the tumor seen in necrosis or old hemorrhage, and larger hepatocellular adenomas may be more heterogeneous than smaller lesions and their CT scan appearance is less specific.
The [[Computed tomography|CT scan]] findings of hepatocellular adenoma are usually variable and characteristic [[Lesion|lesions]] are best seen with multiphase helical [[Computed tomography|CT scanning]]. The [[Computed tomography|CT scan]] findings include non-lobulated and well-marginated mass that can be encapsulated and is rarely [[Calcification|calcified]]. A [[heterogeneous]] hypo-attenuating area within the [[tumor]] may be seen in cases of [[necrosis]] or old [[hemorrhage]]. Large hepatocellular adenomas may be more [[heterogeneous]] than smaller [[Lesion|lesions]] and their [[Computed tomography|CT scan]] appearance is less specific.


==CT==
==CT scan==
* The CT scan appearances of hepatocellular adenoma are usually variable, and classical characteristic lesions of adenoma are best seen with multi-phase helical CT scan.
* The [[Computed tomography|CT scan]] findings of hepatocellular adenoma are usually variable.<ref>{{cite journal|doi=10.1594/ecr2013/C-2620}}</ref>
* The CT scan findings of hepatocellular carcinoma include;
*Classical characteristic [[Lesion|lesions]] of [[adenoma]] are best seen with multi-phase helical [[Computed tomography|CT scan]].
** Non lobulated, well marginated mass that can be encapsulated and is rarely calcified.
* The [[Computed tomography|CT scan]] findings of hepatocellular adenoma include the following:<ref>{{Cite journal
** Homogeneous enhancement in the arterial phase. It is usually isoattenuating but sometimes mildly hypoattenuating relative to normal liver on un enhanced portal venous phase and delayed phase images.
| author = [[Bipin Valchandji Daga]], [[Vaibhav R. Shah]] & [[Rahul B. More]]
** The presence of intratumoral fat can show a hypoattenuating mass, if it is surrounded by a fatty liver it appears hyperattenuating on all contrast phases and unenhanced images.
| title = CT scan diagnosis of hepatic adenoma in a case of von Gierke disease
** A heterogenous, hypoattenuating area within the tumor is seen in necrosis or old hemorrhage.
| journal = [[The Indian journal of radiology & imaging]]
** The larger hepatocellular adenomas may be more heterogeneous than smaller lesions and their CT scan appearance is less specific.
| volume = 22
| issue = 1
| pages = 54–57
| year = 2012
| month = January
| doi = 10.4103/0971-3026.95405
| pmid = 22623817
}}</ref><ref>{{Cite journal
| author = [[Ludger Barthelmes]] & [[Iain S. Tait]]
| title = Liver cell adenoma and liver cell adenomatosis
| journal = [[HPB : the official journal of the International Hepato Pancreato Biliary Association]]
| volume = 7
| issue = 3
| pages = 186–196
| year = 2005
| month =
| doi = 10.1080/13651820510028954
| pmid = 18333188
}}</ref><ref>{{Cite journal
| author = [[T. J. Welch]], [[P. F. 2nd Sheedy]], [[C. M. Johnson]], [[D. H. Stephens]], [[J. W. Charboneau]], [[M. L. Brown]], [[G. R. May]], [[M. A. Adson]] & [[D. B. McGill]]
| title = Focal nodular hyperplasia and hepatic adenoma: comparison of angiography, CT, US, and scintigraphy
| journal = [[Radiology]]
| volume = 156
| issue = 3
| pages = 593–595
| year = 1985
| month = September
| doi = 10.1148/radiology.156.3.3895291
| pmid = 3895291
}}</ref><ref>{{Cite journal
| author = [[H. Dharmana]], [[S. Saravana-Bawan]], [[S. Girgis]] & [[G. Low]]
| title = Hepatocellular adenoma: imaging review of the various molecular subtypes
| journal = [[Clinical radiology]]
| volume = 72
| issue = 4
| pages = 276–285
| year = 2017
| month = April
| doi = 10.1016/j.crad.2016.12.020
| pmid = 28126185
}}</ref><ref name="DhingraFiel2014">{{cite journal|last1=Dhingra|first1=Sadhna|last2=Fiel|first2=M. Isabel|title=Update on the New Classification of Hepatic Adenomas: Clinical, Molecular, and Pathologic Characteristics|journal=Archives of Pathology & Laboratory Medicine|volume=138|issue=8|year=2014|pages=1090–1097|issn=0003-9985|doi=10.5858/arpa.2013-0183-RA}}</ref>
** Non-lobulated and well-marginated [[mass]] that can be encapsulated and is rarely [[Calcification|calcified]].
**[[Homogeneous]] enhancement in the [[Artery|arterial]] phase.  
**The [[homogeneous]] enhancement is usually [[Attenuation|isoattenuating]] but sometimes mildly [[Attenuation|hypo-attenuating]] relative to normal [[liver]] on unenhanced [[Portal vein|portal venous]] phase and delayed phase images.
** Presence of [[Tumoral|intratumoral]] [[fat]] can reveal a [[Attenuation|hypoattenuating]] mass, if it is surrounded by a [[fatty liver]] it appears [[Attenuation|hyperattenuating]] on all [[contrast]] phases and unenhanced images.
** A [[heterogeneous]], [[Attenuation|hypo-attenuating]] area within the [[tumor]] is seen in cases of [[necrosis]] or old [[hemorrhage]].
** Large hepatocellular adenomas may be more [[heterogeneous]] than smaller [[Lesion|lesions]] and their [[Computed tomography|CT scan]] appearance is less specific.
 
==Images==
[[File:Hepatic Adenoma CT (arterial phase).jpg|300px|left|thumb|Axial C+ arterial phase. [https://radiopaedia.org/articles/hepatic-adenoma?lang=us Source: Case courtesy of Dr Natalie Yang, Radiopaedia.org, rID: 6951]]]
[[File:Hepatic Adenoma CT (portal venous phase).jpg|300px|center|thumb|Axial C+ portal venous phase. [https://radiopaedia.org/articles/hepatic-adenoma?lang=us Source: Case courtesy of Dr Natalie Yang, Radiopaedia.org, rID: 6951]]]
[[File:Hepatic Adenoma CT 2.png|300px|left|thumb|Axial C+ portal venous phase. [https://radiopaedia.org/articles/hepatic-adenoma?lang=us Source: Case courtesy of Dr Praveen Jha, Radiopaedia.org, rID: 16678]]]
<br style="clear:left">


==References==
==References==

Latest revision as of 14:41, 21 August 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]Sabawoon Mirwais, M.B.B.S, M.D.[3]

Overview

The CT scan findings of hepatocellular adenoma are usually variable and characteristic lesions are best seen with multiphase helical CT scanning. The CT scan findings include non-lobulated and well-marginated mass that can be encapsulated and is rarely calcified. A heterogeneous hypo-attenuating area within the tumor may be seen in cases of necrosis or old hemorrhage. Large hepatocellular adenomas may be more heterogeneous than smaller lesions and their CT scan appearance is less specific.

CT scan

Images

Axial C+ arterial phase. Source: Case courtesy of Dr Natalie Yang, Radiopaedia.org, rID: 6951
Axial C+ portal venous phase. Source: Case courtesy of Dr Natalie Yang, Radiopaedia.org, rID: 6951
Axial C+ portal venous phase. Source: Case courtesy of Dr Praveen Jha, Radiopaedia.org, rID: 16678


References

  1. . doi:10.1594/ecr2013/C-2620. Missing or empty |title= (help)
  2. Bipin Valchandji Daga, Vaibhav R. Shah & Rahul B. More (2012). "CT scan diagnosis of hepatic adenoma in a case of von Gierke disease". The Indian journal of radiology & imaging. 22 (1): 54–57. doi:10.4103/0971-3026.95405. PMID 22623817. Unknown parameter |month= ignored (help)
  3. Ludger Barthelmes & Iain S. Tait (2005). "Liver cell adenoma and liver cell adenomatosis". HPB : the official journal of the International Hepato Pancreato Biliary Association. 7 (3): 186–196. doi:10.1080/13651820510028954. PMID 18333188.
  4. T. J. Welch, P. F. 2nd Sheedy, C. M. Johnson, D. H. Stephens, J. W. Charboneau, M. L. Brown, G. R. May, M. A. Adson & D. B. McGill (1985). "Focal nodular hyperplasia and hepatic adenoma: comparison of angiography, CT, US, and scintigraphy". Radiology. 156 (3): 593–595. doi:10.1148/radiology.156.3.3895291. PMID 3895291. Unknown parameter |month= ignored (help)
  5. H. Dharmana, S. Saravana-Bawan, S. Girgis & G. Low (2017). "Hepatocellular adenoma: imaging review of the various molecular subtypes". Clinical radiology. 72 (4): 276–285. doi:10.1016/j.crad.2016.12.020. PMID 28126185. Unknown parameter |month= ignored (help)
  6. Dhingra, Sadhna; Fiel, M. Isabel (2014). "Update on the New Classification of Hepatic Adenomas: Clinical, Molecular, and Pathologic Characteristics". Archives of Pathology & Laboratory Medicine. 138 (8): 1090–1097. doi:10.5858/arpa.2013-0183-RA. ISSN 0003-9985.


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