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{{Zollinger-Ellison syndrome}}
{{Zollinger-Ellison syndrome}}
{{CMG}} {{AE}} {{MJK}}
{{CMG}} {{AE}} {{MJK}} {{ARK}}
 
==Overview==
==Overview==
Endoscopic ultrasound and [[Somatostatin receptor]] scintigraphy (SRS) (octreotide scan) may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by gastrinoma.<ref name="TangWu2014">{{cite journal|last1=Tang|first1=Shou-jiang|last2=Wu|first2=Ruonan|last3=Bhaijee|first3=Feriyl|title=Zollinger–Ellison Syndrome|journal=Video Journal and Encyclopedia of GI Endoscopy|volume=1|issue=3-4|year=2014|pages=666–668|issn=22120971|doi=10.1016/j.vjgien.2013.06.005}}</ref>
[[Endoscopic ultrasound]] and [[somatostatin receptor]] scintigraphy (SRS) (octreotide scan) may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by [[gastrinoma]].
 
==Other Imaging Findings==
==Other Imaging Findings==
Other imaging studies that may be helpful in the diagnosis of Zollinger-Ellison syndrome include:
Other imaging studies that may be helpful in the diagnosis of Zollinger-Ellison syndrome include: <ref name="TangWu2014">{{cite journal|last1=Tang|first1=Shou-jiang|last2=Wu|first2=Ruonan|last3=Bhaijee|first3=Feriyl|title=Zollinger–Ellison Syndrome|journal=Video Journal and Encyclopedia of GI Endoscopy|volume=1|issue=3-4|year=2014|pages=666–668|issn=22120971|doi=10.1016/j.vjgien.2013.06.005}}</ref>
*Endoscopic ultrasound<ref name="TangWu2014">{{cite journal|last1=Tang|first1=Shou-jiang|last2=Wu|first2=Ruonan|last3=Bhaijee|first3=Feriyl|title=Zollinger–Ellison Syndrome|journal=Video Journal and Encyclopedia of GI Endoscopy|volume=1|issue=3-4|year=2014|pages=666–668|issn=22120971|doi=10.1016/j.vjgien.2013.06.005}}</ref>
*[[Somatostatin receptor]] scintigraphy (SRS) ([[octreotide]] scan)<ref name="pmid9274481">{{cite journal |vauthors=Cadiot G, Bonnaud G, Lebtahi R, Sarda L, Ruszniewski P, Le Guludec D, Mignon M |title=Usefulness of somatostatin receptor scintigraphy in the management of patients with Zollinger-Ellison syndrome. Groupe de Recherche et d'Etude du Syndrome de Zollinger-Ellison (GRESZE) |journal=Gut |volume=41 |issue=1 |pages=107–14 |year=1997 |pmid=9274481 |pmc=1027237 |doi= |url=}}</ref>
*[[Somatostatin receptor]] scintigraphy (SRS) (octreotide scan)<ref name="pmid9274481">{{cite journal| author=Cadiot G, Bonnaud G, Lebtahi R, Sarda L, Ruszniewski P, Le Guludec D et al.| title=Usefulness of somatostatin receptor scintigraphy in the management of patients with Zollinger-Ellison syndrome. Groupe de Recherche et d'Etude du Syndrome de Zollinger-Ellison (GRESZE). | journal=Gut | year= 1997 | volume= 41 | issue= 1 | pages= 107-14 | pmid=9274481 | doi= | pmc=PMC1027237 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9274481 }} </ref>
*[[Somatostatin receptor]] scintigraphy (SRS) using 111In-pentetreotide with single photon emission tomography ([[SPECT]]) scanning allows total body localization study simultaneously at one time which therefore allows the detection of liver and distant [[metastases]] and it is more sensitive in both localizing the primary [[gastrinoma]] and identifying patients with liver [[metastases]] than conventional methods such as [[CT]], [[MRI]] and [[ultrasound]]. <ref name="pmid8644985">{{cite journal| author=Gibril F, Reynolds JC, Doppman JL, Chen CC, Venzon DJ, Termanini B et al.| title=Somatostatin receptor scintigraphy: its sensitivity compared with that of other imaging methods in detecting primary and metastatic gastrinomas. A prospective study. | journal=Ann Intern Med | year= 1996 | volume= 125 | issue= 1 | pages= 26-34 | pmid=8644985 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8644985 }} </ref>
==Gallery==
<gallery widths=200px>
SRS1.jpg|37-year-old male with MEN 1. The patient was injected with 6.4 mCi In-111 octreotide, and images were acquired in the anterior and posterior projections at 4 hours.Findings are consistent with metastatic somatostatin-receptor-positive malignancy involving the lymph nodes either in the peripancreatic or porta hepatis region.<ref>Wosnitzer, Brian, and Ramesh Gadiraju. 'The Role Of Nuclear Imaging In Multiple Endocrine Neoplasia I (MEN1)'. Radiol. Case Rep. 5.4 (2010): n. pag. Web.</ref>
SRS2.jpg|37-year-old male with MEN 1. The patient was injected with 6.4 mCi In-111 octreotide, and images were acquired in the anterior and posterior projections at 24 hours. Findings are consistent with metastatic somatostatin-receptor-positive malignancy involving the lymph nodes either in the peripancreatic or porta hepatis region.<ref>Wosnitzer, Brian, and Ramesh Gadiraju. 'The Role Of Nuclear Imaging In Multiple Endocrine Neoplasia I (MEN1)'. Radiol. Case Rep. 5.4 (2010): n. pag. Web.</ref>
SRS3.jpg|Axial scan at 24 hours.<ref>Wosnitzer, Brian, and Ramesh Gadiraju. 'The Role Of Nuclear Imaging In Multiple Endocrine Neoplasia I (MEN1)'. Radiol. Case Rep. 5.4 (2010): n. pag. Web.</ref>
SRS4.jpg|Coronal scan at 24 hours.<ref>Wosnitzer, Brian, and Ramesh Gadiraju. 'The Role Of Nuclear Imaging In Multiple Endocrine Neoplasia I (MEN1)'. Radiol. Case Rep. 5.4 (2010): n. pag. Web.</ref>
</gallery>


==References==
==References==

Latest revision as of 16:26, 19 September 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Aravind Reddy Kothagadi M.B.B.S[3]

Overview

Endoscopic ultrasound and somatostatin receptor scintigraphy (SRS) (octreotide scan) may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by gastrinoma.

Other Imaging Findings

Other imaging studies that may be helpful in the diagnosis of Zollinger-Ellison syndrome include: [1]

References

  1. Tang, Shou-jiang; Wu, Ruonan; Bhaijee, Feriyl (2014). "Zollinger–Ellison Syndrome". Video Journal and Encyclopedia of GI Endoscopy. 1 (3–4): 666–668. doi:10.1016/j.vjgien.2013.06.005. ISSN 2212-0971.
  2. Cadiot G, Bonnaud G, Lebtahi R, Sarda L, Ruszniewski P, Le Guludec D, Mignon M (1997). "Usefulness of somatostatin receptor scintigraphy in the management of patients with Zollinger-Ellison syndrome. Groupe de Recherche et d'Etude du Syndrome de Zollinger-Ellison (GRESZE)". Gut. 41 (1): 107–14. PMC 1027237. PMID 9274481.
  3. Gibril F, Reynolds JC, Doppman JL, Chen CC, Venzon DJ, Termanini B; et al. (1996). "Somatostatin receptor scintigraphy: its sensitivity compared with that of other imaging methods in detecting primary and metastatic gastrinomas. A prospective study". Ann Intern Med. 125 (1): 26–34. PMID 8644985.

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