Osteosarcoma biopsy: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Osteosarcoma}} | {{Osteosarcoma}} | ||
{{CMG}};{{AE}} | {{CMG}}; {{AE}}[[User:DrMars|Mohammadmain Rezazadehsaatlou[2]]]. | ||
==Overview== | ==Overview== | ||
Biopsy of osteosarcoma is important for confirming the diagnosis and the determining histologic subtype. | [[Biopsy]] of [[osteosarcoma]] is important for confirming the [[diagnosis]] and the determining histologic subtype. [[Biopsy]] may be performed [[percutaneously]] with either a [[Needle aspiration biopsy|fine-needle]], or wide-bore needle, or through a formal [[incision]]. | ||
==Biopsy== | ==Biopsy== | ||
*Biopsy of osteosarcoma is important for confirming the diagnosis and the determining histologic subtype.<ref>Osteosarcoma. | *[[Biopsy]] of [[osteosarcoma]] is important for confirming the [[diagnosis]] and the determining [[Histology|histologic]] subtype. | ||
* | *[[Biopsy]] procedures include:<ref name="pmid25070231">{{cite journal |vauthors=Moore DD, Luu HH |title=Osteosarcoma |journal=Cancer Treat. Res. |volume=162 |issue= |pages=65–92 |date=2014 |pmid=25070231 |doi=10.1007/978-3-319-07323-1_4 |url=}}</ref><ref name="pmid20179183">{{cite journal |vauthors=Ilaslan H, Schils J, Nageotte W, Lietman SA, Sundaram M |title=Clinical presentation and imaging of bone and soft-tissue sarcomas |journal=Cleve Clin J Med |volume=77 Suppl 1 |issue= |pages=S2–7 |date=March 2010 |pmid=20179183 |doi=10.3949/ccjm.77.s1.01 |url=}}</ref><ref name="pmid21037356">{{cite journal |vauthors=Wu PK, Chen WM, Lee OK, Chen CF, Huang CK, Chen TH |title=The prognosis for patients with osteosarcoma who have received prior manipulative therapy |journal=J Bone Joint Surg Br |volume=92 |issue=11 |pages=1580–5 |date=November 2010 |pmid=21037356 |doi=10.1302/0301-620X.92B11.24706 |url=}}</ref><ref name="pmid29980176">{{cite journal |vauthors=Obiedat H, Alrabadi N, Sultan E, Al Shatti M, Zihlif M |title=The effect of ERCC1 and ERCC2 gene polymorphysims on response to cisplatin based therapy in osteosarcoma patients |journal=BMC Med. Genet. |volume=19 |issue=1 |pages=112 |date=July 2018 |pmid=29980176 |pmc=6035436 |doi=10.1186/s12881-018-0627-4 |url=}}</ref> | ||
*More invasive methods carry a higher risk of complications and contamination of tissue planes. Each year 30% of patients | **'''[[Needle biopsy]]''' | ||
*Inappropriate alignment of the biopsy or inadvertent contamination of soft | *** [[Percutaneously]] with either a [[Needle aspiration biopsy|fine-needle]], or a wide-bore needle | ||
**'''Surgical biopsy''' | |||
***Through a formal [[incision]] | |||
*More [[invasive]] methods carry a higher risk of complications and contamination of tissue planes. | |||
*Each year 30% of patients lose their limbs through inappropriate [[biopsy]] site and technique. | |||
*In principle, [[Biopsy|biopsies]] should be performed at a tumor center by a specialist in tumor surgery. | |||
*Inappropriate alignment of the [[biopsy]] or inadvertent contamination of [[soft tissue]]<nowiki/>s can render subsequent limb-preserving [[Reconstructive surgery|reconstructive]] surgery impossible. | |||
==References== | ==References== | ||
Latest revision as of 13:20, 17 October 2019
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American Roentgen Ray Society Images of Osteosarcoma biopsy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].
Overview
Biopsy of osteosarcoma is important for confirming the diagnosis and the determining histologic subtype. Biopsy may be performed percutaneously with either a fine-needle, or wide-bore needle, or through a formal incision.
Biopsy
- Biopsy of osteosarcoma is important for confirming the diagnosis and the determining histologic subtype.
- Biopsy procedures include:[1][2][3][4]
- Needle biopsy
- Percutaneously with either a fine-needle, or a wide-bore needle
- Surgical biopsy
- Through a formal incision
- Needle biopsy
- More invasive methods carry a higher risk of complications and contamination of tissue planes.
- Each year 30% of patients lose their limbs through inappropriate biopsy site and technique.
- In principle, biopsies should be performed at a tumor center by a specialist in tumor surgery.
- Inappropriate alignment of the biopsy or inadvertent contamination of soft tissues can render subsequent limb-preserving reconstructive surgery impossible.
References
- ↑ Moore DD, Luu HH (2014). "Osteosarcoma". Cancer Treat. Res. 162: 65–92. doi:10.1007/978-3-319-07323-1_4. PMID 25070231.
- ↑ Ilaslan H, Schils J, Nageotte W, Lietman SA, Sundaram M (March 2010). "Clinical presentation and imaging of bone and soft-tissue sarcomas". Cleve Clin J Med. 77 Suppl 1: S2–7. doi:10.3949/ccjm.77.s1.01. PMID 20179183.
- ↑ Wu PK, Chen WM, Lee OK, Chen CF, Huang CK, Chen TH (November 2010). "The prognosis for patients with osteosarcoma who have received prior manipulative therapy". J Bone Joint Surg Br. 92 (11): 1580–5. doi:10.1302/0301-620X.92B11.24706. PMID 21037356.
- ↑ Obiedat H, Alrabadi N, Sultan E, Al Shatti M, Zihlif M (July 2018). "The effect of ERCC1 and ERCC2 gene polymorphysims on response to cisplatin based therapy in osteosarcoma patients". BMC Med. Genet. 19 (1): 112. doi:10.1186/s12881-018-0627-4. PMC 6035436. PMID 29980176.