Osteosarcoma classification: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Osteosarcoma}} | {{Osteosarcoma}} | ||
{{CMG}}; {{AE}}[[User:DrMars|Mohammadmain Rezazadehsaatlou[2]]]. | |||
==Overview== | |||
[[Osteosarcoma]] (OS) is a rare [[bone cancer]] which affects both adolescents and young adults. [[Osteosarcoma]] was classified as primary and secondary. Later the the [[World Health Organization]] sub-typed as [[intramedullary]]/[[central]] and surface [[osteosarcoma]] with a number of sub-types under each group. | |||
==Classification == | |||
* [[Osteosarcoma]] (OS) may be classified into several subtypes based on [[World Health Organization]] and are as follows:<ref name="pmid24002129">{{cite journal |vauthors=Duong LM, Richardson LC |title=Descriptive epidemiology of malignant primary osteosarcoma using population-based registries, United States, 1999-2008 |journal=J Registry Manag |volume=40 |issue=2 |pages=59–64 |date=2013 |pmid=24002129 |pmc=4476493 |doi= |url=}}</ref><ref name="pmid27990273">{{cite journal |vauthors=Bielack SS, Hecker-Nolting S, Blattmann C, Kager L |title=Advances in the management of osteosarcoma |journal=F1000Res |volume=5 |issue= |pages=2767 |date=2016 |pmid=27990273 |pmc=5130082 |doi=10.12688/f1000research.9465.1 |url=}}</ref><ref name="pmid24932027">{{cite journal |vauthors=Kundu ZS |title=Classification, imaging, biopsy and staging of osteosarcoma |journal=Indian J Orthop |volume=48 |issue=3 |pages=238–46 |date=May 2014 |pmid=24932027 |pmc=4052020 |doi=10.4103/0019-5413.132491 |url=}}</ref><ref name="pmid29629690">{{cite journal |vauthors=Misaghi A, Goldin A, Awad M, Kulidjian AA |title=Osteosarcoma: a comprehensive review |journal=SICOT J |volume=4 |issue= |pages=12 |date=2018 |pmid=29629690 |pmc=5890448 |doi=10.1051/sicotj/2017028 |url=}}</ref><ref name="pmid29629690" /><ref name="pmid11920477">{{cite journal |vauthors=Ozaki T, Flege S, Liljenqvist U, Hillmann A, Delling G, Salzer-Kuntschik M, Jürgens H, Kotz R, Winkelmann W, Bielack SS |title=Osteosarcoma of the spine: experience of the Cooperative Osteosarcoma Study Group |journal=Cancer |volume=94 |issue=4 |pages=1069–77 |date=February 2002 |pmid=11920477 |doi= |url=}}</ref><ref name="pmid24002129" /><ref name="pmid12464443">{{cite journal |vauthors=Hamre MR, Severson RK, Chuba P, Lucas DR, Thomas RL, Mott MP |title=Osteosarcoma as a second malignant neoplasm |journal=Radiother Oncol |volume=65 |issue=3 |pages=153–7 |date=December 2002 |pmid=12464443 |doi= |url=}}</ref><ref name="pmid25970361">{{cite journal |vauthors=Barker JP, Monument MJ, Jones KB, Putnam AR, Randall RL |title=Secondary osteosarcoma: is there a predilection for the chondroblastic subtype? |journal=Orthopedics |volume=38 |issue=5 |pages=e359–66 |date=May 2015 |pmid=25970361 |doi=10.3928/01477447-20150504-51 |url=}}</ref> | |||
== | {| class="wikitable" | ||
|+Classification of osteosarcoma | |||
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* Primary [[osteosarcoma]] | |||
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* [[Conventional osteosarcoma|Conventional]]-[[intramedullary]]/central [[High grade osteosarcoma|high grade]] (most common) further sub-typed as: | |||
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* [[Osteoblastic osteosarcoma|Osteoblastic]] (50%) | |||
* [[Chondroblast|Chondroblastic]] (25%) | |||
* [[Fibroblastic]] (25%) | |||
|- | |||
| | |||
* Secondary [[osteosarcoma]] | |||
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* Unusual forms of [[osteosarcoma]] given below are viewed as subtypes of conventional [[osteosarcoma]] because their biological behavior is similar. | |||
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* Osteoblastic [[osteosarcoma]]-sclerosing type | |||
* Osteosarcoma resembling [[osteosarcoma]] | |||
* [[Chondromyxoid fibroma|Chondromyxoid]] fibroma‑like [[osteosarcoma]] | |||
* [[Chondroblastoma]]-like [[osteosarcoma]] | |||
* [[Clear cell tumor|Clear-cell osteosarcoma]] | |||
* [[Malignant]] fibrous [[histiocytoma]]‑like [[osteosarcoma]] | |||
* [[Giant cell]] rich [[osteosarcoma]]-[[Epithelioid]] [[osteosarcoma]] | |||
|} | |||
{| class="wikitable" | |||
|+Osteosarcoma (Primary) subtypes within central and surface tumours | |||
!subtypes | |||
!Osteosarcoma | |||
|- | |||
|CENTRAL (MEDULLARY) | |||
|A. [[Conventional central osteosarcoma|Conventional]] [[High-grade osteosarcoma|high-grade]] central [[osteosarcoma]] (80%) | |||
B. [[Telangiectatic osteosarcoma|Telangiectatic]] [[osteosarcoma]] (4%) | |||
C. [[Intraosseous]] well-differentiated ([[Low-grade osteosarcoma|low-grade]]) [[osteosarcoma]] (1-2%) | |||
D. Small cell [[osteosarcoma]] (1-2%) | |||
|- | |||
|SURFACE (PERIPHERAL) | |||
|a. [[Parosteal osteosarcoma|Parosteal]] (juxtacortical) well-differentiated ([[Low-grade osteosarcoma|low-grade]]) [[osteosarcoma]](4-6%) | |||
b. [[Periosteal osteosarcoma|Periosteal]] [[osteosarcoma]]- low- to intermediate-grade [[osteosarcoma]](<4%) | |||
c. High-grade surface [[osteosarcoma]](1%) | |||
|} | |||
* | |||
* | |||
==References== | ==References== | ||
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[[Category:Musculoskeletal Disease]] | [[Category:Musculoskeletal Disease]] | ||
[[Category:Orthopedics]] | [[Category:Orthopedics]] | ||
[[Category: | [[Category:Up-To-Date]] | ||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Orthopedics]] | |||
Latest revision as of 15:52, 19 October 2019
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Osteosarcoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Osteosarcoma classification On the Web |
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American Roentgen Ray Society Images of Osteosarcoma classification |
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Risk calculators and risk factors for Osteosarcoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].
Overview
Osteosarcoma (OS) is a rare bone cancer which affects both adolescents and young adults. Osteosarcoma was classified as primary and secondary. Later the the World Health Organization sub-typed as intramedullary/central and surface osteosarcoma with a number of sub-types under each group.
Classification
- Osteosarcoma (OS) may be classified into several subtypes based on World Health Organization and are as follows:[1][2][3][4][4][5][1][6][7]
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| subtypes | Osteosarcoma |
|---|---|
| CENTRAL (MEDULLARY) | A. Conventional high-grade central osteosarcoma (80%)
B. Telangiectatic osteosarcoma (4%) C. Intraosseous well-differentiated (low-grade) osteosarcoma (1-2%) D. Small cell osteosarcoma (1-2%) |
| SURFACE (PERIPHERAL) | a. Parosteal (juxtacortical) well-differentiated (low-grade) osteosarcoma(4-6%)
b. Periosteal osteosarcoma- low- to intermediate-grade osteosarcoma(<4%) c. High-grade surface osteosarcoma(1%) |
References
- ↑ 1.0 1.1 Duong LM, Richardson LC (2013). "Descriptive epidemiology of malignant primary osteosarcoma using population-based registries, United States, 1999-2008". J Registry Manag. 40 (2): 59–64. PMC 4476493. PMID 24002129.
- ↑ Bielack SS, Hecker-Nolting S, Blattmann C, Kager L (2016). "Advances in the management of osteosarcoma". F1000Res. 5: 2767. doi:10.12688/f1000research.9465.1. PMC 5130082. PMID 27990273.
- ↑ Kundu ZS (May 2014). "Classification, imaging, biopsy and staging of osteosarcoma". Indian J Orthop. 48 (3): 238–46. doi:10.4103/0019-5413.132491. PMC 4052020. PMID 24932027.
- ↑ 4.0 4.1 Misaghi A, Goldin A, Awad M, Kulidjian AA (2018). "Osteosarcoma: a comprehensive review". SICOT J. 4: 12. doi:10.1051/sicotj/2017028. PMC 5890448. PMID 29629690.
- ↑ Ozaki T, Flege S, Liljenqvist U, Hillmann A, Delling G, Salzer-Kuntschik M, Jürgens H, Kotz R, Winkelmann W, Bielack SS (February 2002). "Osteosarcoma of the spine: experience of the Cooperative Osteosarcoma Study Group". Cancer. 94 (4): 1069–77. PMID 11920477.
- ↑ Hamre MR, Severson RK, Chuba P, Lucas DR, Thomas RL, Mott MP (December 2002). "Osteosarcoma as a second malignant neoplasm". Radiother Oncol. 65 (3): 153–7. PMID 12464443.
- ↑ Barker JP, Monument MJ, Jones KB, Putnam AR, Randall RL (May 2015). "Secondary osteosarcoma: is there a predilection for the chondroblastic subtype?". Orthopedics. 38 (5): e359–66. doi:10.3928/01477447-20150504-51. PMID 25970361.