Osteosarcoma classification: Difference between revisions
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|+Classification of osteosarcoma | |+Classification of osteosarcoma | ||
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* Primary osteosarcoma | * Primary [[osteosarcoma]] | ||
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* [[Conventional osteosarcoma|Conventional]]-[[intramedullary]]/central high grade (most common) further sub-typed as: | * [[Conventional osteosarcoma|Conventional]]-[[intramedullary]]/central [[High grade osteosarcoma|high grade]] (most common) further sub-typed as: | ||
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* [[Osteoblastic osteosarcoma|Osteoblastic]] (50%) | * [[Osteoblastic osteosarcoma|Osteoblastic]] (50%) | ||
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* Secondary | * Secondary [[osteosarcoma]] | ||
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* Unusual forms of [[osteosarcoma]] given below are viewed as subtypes of conventional [[osteosarcoma]] because their biological behavior is similar. | * Unusual forms of [[osteosarcoma]] given below are viewed as subtypes of conventional [[osteosarcoma]] because their biological behavior is similar. | ||
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* Osteoblastic osteosarcoma-sclerosing type | * Osteoblastic [[osteosarcoma]]-sclerosing type | ||
* Osteosarcoma resembling [[osteosarcoma]] | * Osteosarcoma resembling [[osteosarcoma]] | ||
* [[Chondromyxoid fibroma|Chondromyxoid]] fibroma‑like osteosarcoma | * [[Chondromyxoid fibroma|Chondromyxoid]] fibroma‑like [[osteosarcoma]] | ||
* [[Chondroblastoma]]-like osteosarcoma | * [[Chondroblastoma]]-like [[osteosarcoma]] | ||
* [[Clear cell tumor|Clear-cell osteosarcoma]] | * [[Clear cell tumor|Clear-cell osteosarcoma]] | ||
* [[Malignant]] fibrous [[histiocytoma]]‑like osteosarcoma | * [[Malignant]] fibrous [[histiocytoma]]‑like [[osteosarcoma]] | ||
* [[Giant cell]] rich [[osteosarcoma]]-[[Epithelioid]] [[osteosarcoma]] | * [[Giant cell]] rich [[osteosarcoma]]-[[Epithelioid]] [[osteosarcoma]] | ||
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|CENTRAL (MEDULLARY) | |CENTRAL (MEDULLARY) | ||
|A. Conventional high-grade central osteosarcoma (80%) | |A. [[Conventional central osteosarcoma|Conventional]] [[High-grade osteosarcoma|high-grade]] central [[osteosarcoma]] (80%) | ||
B. Telangiectatic osteosarcoma (4%) | B. [[Telangiectatic osteosarcoma|Telangiectatic]] [[osteosarcoma]] (4%) | ||
C. Intraosseous well-differentiated (low-grade) osteosarcoma (1-2%) | C. [[Intraosseous]] well-differentiated ([[Low-grade osteosarcoma|low-grade]]) [[osteosarcoma]] (1-2%) | ||
D. Small cell osteosarcoma (1-2%) | D. Small cell [[osteosarcoma]] (1-2%) | ||
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|SURFACE (PERIPHERAL) | |SURFACE (PERIPHERAL) | ||
|a. Parosteal (juxtacortical) well-differentiated (low-grade) osteosarcoma (4-6%) | |a. [[Parosteal osteosarcoma|Parosteal]] (juxtacortical) well-differentiated ([[Low-grade osteosarcoma|low-grade]]) [[osteosarcoma]](4-6%) | ||
b. Periosteal osteosarcoma - low- to intermediate-grade osteosarcoma (<4%) | b. [[Periosteal osteosarcoma|Periosteal]] [[osteosarcoma]]- low- to intermediate-grade [[osteosarcoma]](<4%) | ||
c. High-grade surface osteosarcoma (1%) | c. High-grade surface [[osteosarcoma]](1%) | ||
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Latest revision as of 15:52, 19 October 2019
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Osteosarcoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Osteosarcoma classification On the Web |
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American Roentgen Ray Society Images of Osteosarcoma classification |
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Risk calculators and risk factors for Osteosarcoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].
Overview
Osteosarcoma (OS) is a rare bone cancer which affects both adolescents and young adults. Osteosarcoma was classified as primary and secondary. Later the the World Health Organization sub-typed as intramedullary/central and surface osteosarcoma with a number of sub-types under each group.
Classification
- Osteosarcoma (OS) may be classified into several subtypes based on World Health Organization and are as follows:[1][2][3][4][4][5][1][6][7]
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| subtypes | Osteosarcoma |
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| CENTRAL (MEDULLARY) | A. Conventional high-grade central osteosarcoma (80%)
B. Telangiectatic osteosarcoma (4%) C. Intraosseous well-differentiated (low-grade) osteosarcoma (1-2%) D. Small cell osteosarcoma (1-2%) |
| SURFACE (PERIPHERAL) | a. Parosteal (juxtacortical) well-differentiated (low-grade) osteosarcoma(4-6%)
b. Periosteal osteosarcoma- low- to intermediate-grade osteosarcoma(<4%) c. High-grade surface osteosarcoma(1%) |
References
- ↑ 1.0 1.1 Duong LM, Richardson LC (2013). "Descriptive epidemiology of malignant primary osteosarcoma using population-based registries, United States, 1999-2008". J Registry Manag. 40 (2): 59–64. PMC 4476493. PMID 24002129.
- ↑ Bielack SS, Hecker-Nolting S, Blattmann C, Kager L (2016). "Advances in the management of osteosarcoma". F1000Res. 5: 2767. doi:10.12688/f1000research.9465.1. PMC 5130082. PMID 27990273.
- ↑ Kundu ZS (May 2014). "Classification, imaging, biopsy and staging of osteosarcoma". Indian J Orthop. 48 (3): 238–46. doi:10.4103/0019-5413.132491. PMC 4052020. PMID 24932027.
- ↑ 4.0 4.1 Misaghi A, Goldin A, Awad M, Kulidjian AA (2018). "Osteosarcoma: a comprehensive review". SICOT J. 4: 12. doi:10.1051/sicotj/2017028. PMC 5890448. PMID 29629690.
- ↑ Ozaki T, Flege S, Liljenqvist U, Hillmann A, Delling G, Salzer-Kuntschik M, Jürgens H, Kotz R, Winkelmann W, Bielack SS (February 2002). "Osteosarcoma of the spine: experience of the Cooperative Osteosarcoma Study Group". Cancer. 94 (4): 1069–77. PMID 11920477.
- ↑ Hamre MR, Severson RK, Chuba P, Lucas DR, Thomas RL, Mott MP (December 2002). "Osteosarcoma as a second malignant neoplasm". Radiother Oncol. 65 (3): 153–7. PMID 12464443.
- ↑ Barker JP, Monument MJ, Jones KB, Putnam AR, Randall RL (May 2015). "Secondary osteosarcoma: is there a predilection for the chondroblastic subtype?". Orthopedics. 38 (5): e359–66. doi:10.3928/01477447-20150504-51. PMID 25970361.