Amyloidosis CT: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Amyloidosis}} | {{Amyloidosis}} | ||
{{CMG}} | {{CMG}} {{shyam}}; {{AE}} {{SHH}}{{Sab}} | ||
== Overview == | |||
==Overview== | |||
CT can be done to assess for amyloid deposition in particular organs. It can also be done to rule out other causes of organ dysfunction. However, MRI is more sensitive than CT in the diagnosis of amyloidosis. | |||
==CT== | ==CT== | ||
In hepatic amyloidosis the CT scan findings may include: | |||
* Liver enlargement with heterogeneous decreased attenuation | |||
* Asymmetric and triangular hepatomegaly with the apex at the falciform ligament (due to mild atrophic change of the lateral border of both hepatic lobes) | |||
* Parenchyma calcification (rare) | |||
In renal amyloidosis the CT findings may include: | |||
* Kidney enlargement with heterogeneous decreased attenuation | |||
* Parenchyma calcification (rare) | |||
In cardiac amyloidosis the CT findings may include<ref name="pmid24847009">{{cite journal| author=Falk RH, Quarta CC, Dorbala S| title=How to image cardiac amyloidosis. | journal=Circ Cardiovasc Imaging | year= 2014 | volume= 7 | issue= 3 | pages= 552-62 | pmid=24847009 | doi=10.1161/CIRCIMAGING.113.001396 | pmc=4118308 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24847009 }} </ref>: | |||
* Heart enlargement with heterogeneous decreased attenuation | |||
* Cardiac calcifications | |||
* Pericardial effusion (rare) | |||
===Images=== | |||
[[File:Amyloidoma-mediastinal-1.jpg|300px|left|thumb| CT image showing mediastinal amyloidosis (yellow arrows). Case courtesy of Dr Natalie Yang, Radiopaedia.org, rID: 6711]] | |||
[[File:Amyloidosis-bronchial-and-diffuse-nodular-pulmonary-involvement.jpg|300px|center|thumb| Amyloidosis - bronchial and diffuse nodular pulmonary involvement. Case courtesy of Dr Bruno Di Muzio, Radiopaedia.org, rID: 60156]] | |||
<br style="clear:left"> | |||
== References == | == References == | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Disease]] | |||
[[Category:Rheumatology]] | |||
[[Category:Cardiology]] | |||
[[Category:Endocrinology]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 01:24, 26 October 2019
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Amyloidosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Amyloidosis CT On the Web |
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American Roentgen Ray Society Images of Amyloidosis CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[3]Sabawoon Mirwais, M.B.B.S, M.D.[4]
Overview
CT can be done to assess for amyloid deposition in particular organs. It can also be done to rule out other causes of organ dysfunction. However, MRI is more sensitive than CT in the diagnosis of amyloidosis.
CT
In hepatic amyloidosis the CT scan findings may include:
- Liver enlargement with heterogeneous decreased attenuation
- Asymmetric and triangular hepatomegaly with the apex at the falciform ligament (due to mild atrophic change of the lateral border of both hepatic lobes)
- Parenchyma calcification (rare)
In renal amyloidosis the CT findings may include:
- Kidney enlargement with heterogeneous decreased attenuation
- Parenchyma calcification (rare)
In cardiac amyloidosis the CT findings may include[1]:
- Heart enlargement with heterogeneous decreased attenuation
- Cardiac calcifications
- Pericardial effusion (rare)
Images
References
- ↑ Falk RH, Quarta CC, Dorbala S (2014). "How to image cardiac amyloidosis". Circ Cardiovasc Imaging. 7 (3): 552–62. doi:10.1161/CIRCIMAGING.113.001396. PMC 4118308. PMID 24847009.