Teratoma surgery: Difference between revisions
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==Surgery== | ==Surgery== | ||
*Surgical intervention is the mainstay of treatment for mature teratoma and immature teratoma stage I in children.<ref name="pmid6684416">{{cite journal| author=Tapper D, Lack EE| title=Teratomas in infancy and childhood. A 54-year experience at the Children's Hospital Medical Center. | journal=Ann Surg | year= 1983 | volume= 198 | issue= 3 | pages= 398-410 | pmid=6684416 | doi=10.1097/00000658-198309000-00016 | pmc=1353316 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6684416 }} </ref><ref name="GöbelSchneider2000">{{cite journal|last1=Göbel|first1=U.|last2=Schneider|first2=D. T.|last3=Calaminus|first3=G.|last4=Haas|first4=R. J.|last5=Schmidt|first5=P.|last6=Harms|first6=D.|title=Germ-cell tumors in childhood and adolescence|journal=Annals of Oncology|volume=11|issue=3|year=2000|pages=263–271|issn=0923-7534|doi=10.1023/A:1008360523160}}</ref><ref name="pmid10561269">{{cite journal| author=Marina NM, Cushing B, Giller R, Cohen L, Lauer SJ, Ablin A et al.| title=Complete surgical excision is effective treatment for children with immature teratomas with or without malignant elements: A Pediatric Oncology Group/Children's Cancer Group Intergroup Study. | journal=J Clin Oncol | year= 1999 | volume= 17 | issue= 7 | pages= 2137-43 | pmid=10561269 | doi=10.1200/JCO.1999.17.7.2137 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10561269 }} </ref> | *Surgical intervention is the mainstay of treatment for mature teratoma and immature teratoma stage I in children.<ref name="pmid6684416">{{cite journal| author=Tapper D, Lack EE| title=Teratomas in infancy and childhood. A 54-year experience at the Children's Hospital Medical Center. | journal=Ann Surg | year= 1983 | volume= 198 | issue= 3 | pages= 398-410 | pmid=6684416 | doi=10.1097/00000658-198309000-00016 | pmc=1353316 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6684416 }} </ref><ref name="GöbelSchneider2000">{{cite journal|last1=Göbel|first1=U.|last2=Schneider|first2=D. T.|last3=Calaminus|first3=G.|last4=Haas|first4=R. J.|last5=Schmidt|first5=P.|last6=Harms|first6=D.|title=Germ-cell tumors in childhood and adolescence|journal=Annals of Oncology|volume=11|issue=3|year=2000|pages=263–271|issn=0923-7534|doi=10.1023/A:1008360523160}}</ref><ref name="pmid10561269">{{cite journal| author=Marina NM, Cushing B, Giller R, Cohen L, Lauer SJ, Ablin A et al.| title=Complete surgical excision is effective treatment for children with immature teratomas with or without malignant elements: A Pediatric Oncology Group/Children's Cancer Group Intergroup Study. | journal=J Clin Oncol | year= 1999 | volume= 17 | issue= 7 | pages= 2137-43 | pmid=10561269 | doi=10.1200/JCO.1999.17.7.2137 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10561269 }} </ref> | ||
*Observation after surgery is very important with serial of follow up exams and serum alpha fetoprotein.<ref name="pmid27786428">{{cite journal| author=Egler RA, Gosiengfiao Y, Russell H, Wickiser JE, Frazier AL| title=Is surgical resection and observation sufficient for stage I and II sacrococcygeal germ cell tumors? A case series and review. | journal=Pediatr Blood Cancer | year= 2017 | volume= 64 | issue= 5 | pages= | pmid=27786428 | doi=10.1002/pbc.26311 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27786428 }} </ref> | *Observation after surgery is very important with serial of follow up exams and serum alpha fetoprotein.<ref name="pmid27786428">{{cite journal| author=Egler RA, Gosiengfiao Y, Russell H, Wickiser JE, Frazier AL| title=Is surgical resection and observation sufficient for stage I and II sacrococcygeal germ cell tumors? A case series and review. | journal=Pediatr Blood Cancer | year= 2017 | volume= 64 | issue= 5 | pages= | pmid=27786428 | doi=10.1002/pbc.26311 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27786428 }} </ref><ref name="pmid29447817">{{cite journal| author=Dharmarajan H, Rouillard-Bazinet N, Chandy BM| title=Mature and immature pediatric head and neck teratomas: A 15-year review at a large tertiary center. | journal=Int J Pediatr Otorhinolaryngol | year= 2018 | volume= 105 | issue= | pages= 43-47 | pmid=29447817 | doi=10.1016/j.ijporl.2017.11.031 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29447817 }} </ref> | ||
*Surgery with fertility sparing and chemotherapy are indicated for immature teratoma stage II-IV in aldults.<ref name="pmid1260722">{{cite journal| author=Norris HJ, Zirkin HJ, Benson WL| title=Immature (malignant) teratoma of the ovary: a clinical and pathologic study of 58 cases. | journal=Cancer | year= 1976 | volume= 37 | issue= 5 | pages= 2359-72 | pmid=1260722 | doi=10.1002/1097-0142(197605)37:5<2359::aid-cncr2820370528>3.0.co;2-q | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1260722 }} </ref> | *Surgery with fertility sparing and chemotherapy are indicated for immature teratoma stage II-IV in aldults.<ref name="pmid1260722">{{cite journal| author=Norris HJ, Zirkin HJ, Benson WL| title=Immature (malignant) teratoma of the ovary: a clinical and pathologic study of 58 cases. | journal=Cancer | year= 1976 | volume= 37 | issue= 5 | pages= 2359-72 | pmid=1260722 | doi=10.1002/1097-0142(197605)37:5<2359::aid-cncr2820370528>3.0.co;2-q | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1260722 }} </ref> | ||
Latest revision as of 20:19, 22 November 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2]
Overview
Surgical intervention is the mainstay of treatment for teratoma.
Surgery
- Surgical intervention is the mainstay of treatment for mature teratoma and immature teratoma stage I in children.[1][2][3]
- Observation after surgery is very important with serial of follow up exams and serum alpha fetoprotein.[4][5]
- Surgery with fertility sparing and chemotherapy are indicated for immature teratoma stage II-IV in aldults.[6]
References
- ↑ Tapper D, Lack EE (1983). "Teratomas in infancy and childhood. A 54-year experience at the Children's Hospital Medical Center". Ann Surg. 198 (3): 398–410. doi:10.1097/00000658-198309000-00016. PMC 1353316. PMID 6684416.
- ↑ Göbel, U.; Schneider, D. T.; Calaminus, G.; Haas, R. J.; Schmidt, P.; Harms, D. (2000). "Germ-cell tumors in childhood and adolescence". Annals of Oncology. 11 (3): 263–271. doi:10.1023/A:1008360523160. ISSN 0923-7534.
- ↑ Marina NM, Cushing B, Giller R, Cohen L, Lauer SJ, Ablin A; et al. (1999). "Complete surgical excision is effective treatment for children with immature teratomas with or without malignant elements: A Pediatric Oncology Group/Children's Cancer Group Intergroup Study". J Clin Oncol. 17 (7): 2137–43. doi:10.1200/JCO.1999.17.7.2137. PMID 10561269.
- ↑ Egler RA, Gosiengfiao Y, Russell H, Wickiser JE, Frazier AL (2017). "Is surgical resection and observation sufficient for stage I and II sacrococcygeal germ cell tumors? A case series and review". Pediatr Blood Cancer. 64 (5). doi:10.1002/pbc.26311. PMID 27786428.
- ↑ Dharmarajan H, Rouillard-Bazinet N, Chandy BM (2018). "Mature and immature pediatric head and neck teratomas: A 15-year review at a large tertiary center". Int J Pediatr Otorhinolaryngol. 105: 43–47. doi:10.1016/j.ijporl.2017.11.031. PMID 29447817.
- ↑ Norris HJ, Zirkin HJ, Benson WL (1976). "Immature (malignant) teratoma of the ovary: a clinical and pathologic study of 58 cases". Cancer. 37 (5): 2359–72. doi:10.1002/1097-0142(197605)37:5<2359::aid-cncr2820370528>3.0.co;2-q. PMID 1260722.