Mitral regurgitation epidemiology and demographics: Difference between revisions
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{{Mitral regurgitation}} | {{Mitral regurgitation}} | ||
{{CMG}}; {{AE}} [[Varun Kumar]], M.B.B.S. | {{CMG}}; {{AE}} [[Varun Kumar]], M.B.B.S., [[Lakshmi Gopalakrishnan]], M.B.B.S., {{Rim}} | ||
==Overview== | ==Overview== | ||
Mitral regurgitation (MR) is one of the most common [[valvular disease]]s in the general population, ranking first among valvular regurgitation abnormailities. The prevalence of MR of a severity equal to or more than mild was reported in The Framingham Heart Study as 19.0% in men and 19.1% in women. The prevalence of MR increases with age. | |||
== | ==Prevalence== | ||
* The Framingham Heart Study, a prospective epidemiologic study, evaluated the [[prevalence]] and severity of MR and other valvular diseases by color [[Doppler]] examinations in 1,696 men and 1,893 women. | |||
The Framingham Heart Study, a prospective epidemiologic study, evaluated the [[prevalence]] and severity of MR and other valvular diseases by color [[Doppler]] examinations in 1,696 men and 1,893 women. | * The study revealed that MR is the most common valvular regurgitation in the general population, followed by [[tricuspid regurgitation]] and then [[aortic regurgitation]]. | ||
* The prevalence of MR (with a severity ranging from trace to ≥ moderate regurgitation) was 87.7% in men and 91.5% in women. | |||
* When trace regurgitation is excluded, the prevalence of MR of a severity ≥ mild was 19.0% in men and 19.1% in women. | |||
* The elevated prevalence of trace regurgitation can be a normal finding related to an artifact or an anatomic characteristic of the closure of the [[mitral valve]].<ref name="pmid10190406">{{cite journal| author=Singh JP, Evans JC, Levy D, Larson MG, Freed LA, Fuller DL et al.| title=Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study) | journal=Am J Cardiol | year= 1999 | volume= 83 | issue= 6 | pages= 897-902 | pmid=10190406 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10190406 }} </ref><ref name="pmid101904062">{{cite journal| author=Singh JP, Evans JC, Levy D, Larson MG, Freed LA, Fuller DL et al.| title=Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study) | journal=Am J Cardiol | year= 1999 | volume= 83 | issue= 6 | pages= 897-902 | pmid=10190406 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10190406 }}</ref> | |||
==Age== | ==Age== | ||
The prevalence of | |||
* The prevalence of MR increases with age. MR is one of the most common valvular heart disease in the elderly. | |||
* Shown below are tables depicting the prevalence of MR by age and severity in men and women according the results of the Framingham Heart Study.<ref name="pmid10190406">{{cite journal| author=Singh JP, Evans JC, Levy D, Larson MG, Freed LA, Fuller DL et al.| title=Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study) | journal=Am J Cardiol | year= 1999 | volume= 83 | issue= 6 | pages= 897-902 | pmid=10190406 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10190406 }} </ref> | |||
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==Gender== | ==Gender== | ||
Overall, mitral regurgitation affects both males and females equally. | |||
* Overall, mitral regurgitation affects both males and females equally. However, there are some minor differences when age is considered. | |||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Varun Kumar, M.B.B.S., Lakshmi Gopalakrishnan, M.B.B.S., Rim Halaby, M.D. [2]
Overview
Mitral regurgitation (MR) is one of the most common valvular diseases in the general population, ranking first among valvular regurgitation abnormailities. The prevalence of MR of a severity equal to or more than mild was reported in The Framingham Heart Study as 19.0% in men and 19.1% in women. The prevalence of MR increases with age.
Prevalence
- The Framingham Heart Study, a prospective epidemiologic study, evaluated the prevalence and severity of MR and other valvular diseases by color Doppler examinations in 1,696 men and 1,893 women.
- The study revealed that MR is the most common valvular regurgitation in the general population, followed by tricuspid regurgitation and then aortic regurgitation.
- The prevalence of MR (with a severity ranging from trace to ≥ moderate regurgitation) was 87.7% in men and 91.5% in women.
- When trace regurgitation is excluded, the prevalence of MR of a severity ≥ mild was 19.0% in men and 19.1% in women.
- The elevated prevalence of trace regurgitation can be a normal finding related to an artifact or an anatomic characteristic of the closure of the mitral valve.[1][2]
Age
- The prevalence of MR increases with age. MR is one of the most common valvular heart disease in the elderly.
- Shown below are tables depicting the prevalence of MR by age and severity in men and women according the results of the Framingham Heart Study.[1]
| Severity of MR | Prevalence of MR by age in men | ||||
| 26-29 | 40-49 | 50-59 | 60-69 | 70-83 | |
| No MR (%) | 14.4 | 13.3 | 11.3 | 12.7 | 9.0 |
| Trace (%) | 76.7 | 72.9 | 74.6 | 60.3 | 51.7 |
| Mild (%) | 8.9 | 13.5 | 12.5 | 24.6 | 28.1 |
| Moderate or severe (%) | 0 | 0.3 | 1.6 | 2.4 | 11.2 |
| Severity of MR | Prevalence of MR by age in women | ||||
| 26-29 | 40-49 | 50-59 | 60-69 | 70-83 | |
| No MR (%) | 14.0 | 8.6 | 9.0 | 7.2 | 5.6 |
| Trace (%) | 76.3 | 75 | 74 | 66.5 | 70.8 |
| Mild (%) | 9.7 | 15.5 | 16 | 24 | 23.6 |
| Moderate or severe (%) | 0 | 0.9 | 1 | 2.3 | 0 |
Gender
- Overall, mitral regurgitation affects both males and females equally. However, there are some minor differences when age is considered.
References
- ↑ 1.0 1.1 Singh JP, Evans JC, Levy D, Larson MG, Freed LA, Fuller DL; et al. (1999). "Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study)". Am J Cardiol. 83 (6): 897–902. PMID 10190406.
- ↑ Singh JP, Evans JC, Levy D, Larson MG, Freed LA, Fuller DL; et al. (1999). "Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study)". Am J Cardiol. 83 (6): 897–902. PMID 10190406.