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== [[Spondyloarthropathy overview|Overview]] ==


'''Spondyloarthropathies''' are inflammatory joint diseases associated with the [[Major_histocompatibility_complex|MHC]] class I molecule [[HLA-B27]]. The term '''seronegative spondylarthropathy''' is used by medical practitioners because this set of conditions may mimic rheumatoid diseases such as [[rheumatoid arthritis]], but [[serological]] (blood) tests are typically negative for [[rheumatoid factor|rheumatoid factor (RhF)]].
== [[Spondyloarthropathy historical perspective|Historical Perspective]] ==


Subgroups (with increased HLA-B27 frequency) are:
== [[Spondyloarthropathy classification|Classification]] ==
*[[ankylosing spondylitis]] Caucasians (AS, 92%),
*[[ankylosing spondylitis]] African-Americans (AS, 50%),
*[[reactive arthritis]] (Reiter's syndrome) (RS, 60-80%),
*[[enteropathic]] arthritis associated with [[inflammatory bowel disease]] (IBD, 60%),
*[[Psoriatic arthritis]] (60%),
*isolated acute anterior uveitis (AAU, iritis or iridocyclitis, 50%), and
*undifferentiated SpA (USpA, 20-25%).


[[Whipple disease]] and [[Behçet disease]] may also be linked to HLA-B27, as may undifferentiated spondyloarthropathy.
== [[Spondyloarthropathy pathophysiology|Pathophysiology]] ==
 
== [[Spondyloarthropathy causes|Causes]] ==
 
== [[Spondyloarthropathies differential diagnosis|Differentiating Spondyloarthropathies from other Disease]] ==
 
== [[Spondyloarthropathy epidemiology and demographics|Epidemiology and Demographics]] ==
 
== [[Spondyloarthropathy risk factors|Risk Factors]] ==
 
== [[Spondyloarthropathy screening|Screening]] ==
 
== [[Spondyloarthropathy natural history, complications and prognosis|Natural History, Complications and Prognosis]] ==
 
== Diagnosis ==
[[Spondyloarthropathy diagnostic study of choice|Diagnostic Study of Choice]] | [[Spondyloarthropathy history and symptoms|History and symptoms]] | [[Spondyloarthropathy physical examination|Physical Examination]] | [[Spondyloarthropathy laboratory findings|Laboratory Findings]] | [[Spondyloarthropathy electrocardiogram|Electrocardiogram]] | [[Spondyloarthropathy x ray|X-Ray]] | [[Spondyloarthropathy echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Spondyloarthropathy CT scan|CT Scan]] | [[Spondyloarthropathy MRI|MRI]] | [[Spondyloarthropathy other imaging findings|Other Imaging Findings]] | [[Spondyloarthropathy other diagnostic studies|Other diagnostic Studies]]
 
== Treatment ==
[[Spondyloarthropathy medical therapy|Medical Therapy]] | [[Spondyloarthropathy interventions|Interventions]] | [[Spondyloarthropathy surgery|Surgery]] | [[Spondyloarthropathy primary prevention|Primary Prevention]] | [[Spondyloarthropathy secondary prevention|Secondary Prevention]] | [[Spondyloarthropathy cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | Future or Investigational Therapies
 
==References==


[[Category:Musculoskeletal disorders]]


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Latest revision as of 14:25, 1 June 2020

Spondyloarthropathy Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating spondyloarthropathies from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Interventions

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

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Case #1

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Echo & Ultrasound
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MRI

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US National Guidelines Clearinghouse

NICE Guidance

FDA on Spondyloarthropathy

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Risk calculators and risk factors for Spondyloarthropathy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Arash Azhideh

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Spondyloarthropathies from other Disease

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice | History and symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X-Ray | Echocardiography and Ultrasound | CT Scan | MRI | Other Imaging Findings | Other diagnostic Studies

Treatment

Medical Therapy | Interventions | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

References

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