Pheochromocytoma other imaging findings: Difference between revisions
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==Other Imaging Findings== | ==Other Imaging Findings== | ||
Other imaging studies | Other imaging studies for [[pheochormocytoma]] include:<ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_94_toc</ref> | ||
* <sup>123</sup>I-[[metaiodobenzylguanidine]] (MIBG) [[scintigraphy]] | * <sup>123</sup>I-[[metaiodobenzylguanidine]] (MIBG) [[scintigraphy]] | ||
** Done in case of negative or inconclusive [[CT]] and [[Magnetic resonance imaging|MRI]] | |||
** Demonstrates the uptake of the compound by [[tumor]] cells which is analogous to [[norepinephrine]] uptake by [[adrenergic]] [[tissues]]<ref name="pmid1787652">{{cite journal| author=Bravo EL| title=Pheochromocytoma: new concepts and future trends. | journal=Kidney Int | year= 1991 | volume= 40 | issue= 3 | pages= 544-56 | pmid=1787652 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1787652 }}</ref> | |||
* <sup>111</sup>In-[[octreotide]] [[scintigraphy]]<ref name="pmid10197697">{{cite journal| author=Lin JC, Palafox BA, Jackson HA, Cohen AJ, Gazzaniga AB| title=Cardiac pheochromocytoma: resection after diagnosis by 111-indium octreotide scan. | journal=Ann Thorac Surg | year= 1999 | volume= 67 | issue= 2 | pages= 555-8 | pmid=10197697 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10197697 }}</ref> | * <sup>111</sup>In-[[octreotide]] [[scintigraphy]]<ref name="pmid10197697">{{cite journal| author=Lin JC, Palafox BA, Jackson HA, Cohen AJ, Gazzaniga AB| title=Cardiac pheochromocytoma: resection after diagnosis by 111-indium octreotide scan. | journal=Ann Thorac Surg | year= 1999 | volume= 67 | issue= 2 | pages= 555-8 | pmid=10197697 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10197697 }}</ref> | ||
* <sup>18</sup>F-[[fluorodeoxyglucose]] [[positron emission tomography]] | |||
* <sup>18</sup>F-[[fluorodeoxyglucose]] [[positron emission tomography]] | ** More sensitive than I-MIBG | ||
* [[PET scan|PET CT]] | |||
* [[PET scan|PET CT]] | ** High [[sensitivity]] for small lesions | ||
* [[Adrenal gland|Adrenal]] venous sampling (AVS) | ** More [[Sensitivity (test)|sensitive]] than I-MIBG | ||
* [[Image-guided surgery|Image-guided needle biopsy]] | * [[Adrenal gland|Adrenal]] venous sampling (AVS) | ||
** High false positive results<ref name="pmid20061413">{{cite journal| author=Freel EM, Stanson AW, Thompson GB, Grant CS, Farley DR, Richards ML et al.| title=Adrenal venous sampling for catecholamines: a normal value study. | journal=J Clin Endocrinol Metab | year= 2010 | volume= 95 | issue= 3 | pages= 1328-32 | pmid=20061413 | doi=10.1210/jc.2009-2253 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20061413 }}</ref> | |||
* [[Image-guided surgery|Image-guided needle biopsy]] | |||
** Associated with many surgical complications<ref name="pmid19958944">{{cite journal| author=Vanderveen KA, Thompson SM, Callstrom MR, Young WF, Grant CS, Farley DR et al.| title=Biopsy of pheochromocytomas and paragangliomas: potential for disaster. | journal=Surgery | year= 2009 | volume= 146 | issue= 6 | pages= 1158-66 | pmid=19958944 | doi=10.1016/j.surg.2009.09.013 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19958944 }}</ref> | |||
[[File:Mbig.gif|250px|left|thumb|MBIG of pheochromocytoma, SOURCE: Case courtesy of Dr Roberto Schubert, Radiopaedia.org, rID: 16148]] | |||
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==References== | ==References== | ||
Latest revision as of 22:01, 28 July 2020
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Pheochromocytoma Microchapters |
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Pheochromocytoma other imaging findings On the Web |
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American Roentgen Ray Society Images of Pheochromocytoma other imaging findings |
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Risk calculators and risk factors for Pheochromocytoma other imaging findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]
Overview
123I-metaiodobenzylguanidine (MIBG) scintigraphy coupled with CT scan imaging can be used for the localization of distant metastasis of pheochromocytoma.
Other Imaging Findings
Other imaging studies for pheochormocytoma include:[1]
- 123I-metaiodobenzylguanidine (MIBG) scintigraphy
- Done in case of negative or inconclusive CT and MRI
- Demonstrates the uptake of the compound by tumor cells which is analogous to norepinephrine uptake by adrenergic tissues[2]
- 111In-octreotide scintigraphy[3]
- 18F-fluorodeoxyglucose positron emission tomography
- More sensitive than I-MIBG
- PET CT
- High sensitivity for small lesions
- More sensitive than I-MIBG
- Adrenal venous sampling (AVS)
- High false positive results[4]
- Image-guided needle biopsy
- Associated with many surgical complications[5]
References
- ↑ National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_94_toc
- ↑ Bravo EL (1991). "Pheochromocytoma: new concepts and future trends". Kidney Int. 40 (3): 544–56. PMID 1787652.
- ↑ Lin JC, Palafox BA, Jackson HA, Cohen AJ, Gazzaniga AB (1999). "Cardiac pheochromocytoma: resection after diagnosis by 111-indium octreotide scan". Ann Thorac Surg. 67 (2): 555–8. PMID 10197697.
- ↑ Freel EM, Stanson AW, Thompson GB, Grant CS, Farley DR, Richards ML; et al. (2010). "Adrenal venous sampling for catecholamines: a normal value study". J Clin Endocrinol Metab. 95 (3): 1328–32. doi:10.1210/jc.2009-2253. PMID 20061413.
- ↑ Vanderveen KA, Thompson SM, Callstrom MR, Young WF, Grant CS, Farley DR; et al. (2009). "Biopsy of pheochromocytomas and paragangliomas: potential for disaster". Surgery. 146 (6): 1158–66. doi:10.1016/j.surg.2009.09.013. PMID 19958944.