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==Overview==
==Overview==
African trypanosomiasis is a human tropical [[parasitic]] [[disease]] usually caused by [[protozoan]] hemo-flagellates belonging to the complex ''[[Trypanosoma brucei]]''. Two [[subspecies]] that are [[Morphology (biology)|morphologically]] indistinguishable cause distinct [[disease]] patterns in humans. [[Trypanosoma brucei gambiense|''Trypanosoma brucei gambiense'']] causes [[African trypanosomiasis|West African sleeping sickness]] and [[Trypanosoma brucei rhodesiense|''Trypanosoma brucei rhodesiense'']] causes [[East African sleeping sickness]].
==Causes==
[[Protozoan]] hemo-flagellates belonging to the complex ''[[Trypanosoma brucei]]'' cause African trypanosomiasis. Two [[subspecies]] that are [[Morphology (biology)|morphologically]] indistinguishable cause distinct [[disease]] patterns in humans. [[Trypanosoma brucei gambiense|''Trypanosoma brucei'' ''gambiense'']] causes [[Sleeping sickness (West African)|West African sleeping sickness]] and [[Trypanosoma brucei rhodesiense|''Trypanosoma brucei'' ''rhodesiense'']] causes [[East African sleeping sickness]].
===East African Trypanosomiasis===
* The [[disease]] is caused by a [[Parasites|parasite]] named ''[[Trypanosoma brucei rhodesiense]]'', carried by the [[tsetse fly]].
* An individual will contract [[African trypanosomiasis|East African trypanosomiasis]] if they are bitten by a [[tsetse fly]] [[infected]] with the ''[[Trypanosoma brucei rhodesiense]]'' parasite.
* The [[tsetse fly]] is common only in Africa.
===West African Trypanosomiasis===
* West African trypanosomiasis, also called Gambian [[sleeping sickness]], is caused by a [[Parasites|parasite]] called [[Trypanosoma brucei gambiense|''Trypanosoma brucei gambiense'']] carried by the [[tsetse fly]].
* An individual gets [[African trypanosomiasis|West African trypanosomiasis]] through the bite of an infected [[tsetse fly]], found only in Africa. 
* On rare occasions, a [[pregnant]] woman may pass the [[infection]] to her baby, or an individual may become infected through a [[blood transfusion]] or [[organ transplant]].<ref>http://www.dpd.cdc.gov/dpdx/HTML/TrypanosomiasisAfrican.htm
http://www.cdc.gov/ncidod/dpd/parasites/trypanosomiasis/factsht_ea_trypanosomiasis.htm#what
http://www.cdc.gov/ncidod/dpd/parasites/trypanosomiasis/factsht_wa_trypanosomiasis.htm
</ref>


==References==
==References==
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Latest revision as of 20:19, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Pilar Almonacid

Overview

African trypanosomiasis is a human tropical parasitic disease usually caused by protozoan hemo-flagellates belonging to the complex Trypanosoma brucei. Two subspecies that are morphologically indistinguishable cause distinct disease patterns in humans. Trypanosoma brucei gambiense causes West African sleeping sickness and Trypanosoma brucei rhodesiense causes East African sleeping sickness.

Causes

Protozoan hemo-flagellates belonging to the complex Trypanosoma brucei cause African trypanosomiasis. Two subspecies that are morphologically indistinguishable cause distinct disease patterns in humans. Trypanosoma brucei gambiense causes West African sleeping sickness and Trypanosoma brucei rhodesiense causes East African sleeping sickness.

East African Trypanosomiasis

West African Trypanosomiasis

References