Alcoholic liver disease other imaging findings: Difference between revisions
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==Overview== | ==Overview== | ||
There have been recent advances towards newer imaging modalities to help detect and quantify [[hepatic]] [[fibrosis]] and [[cirrhosis]]. These investigations are comparable to the gold standard that is [[liver biopsy]] to confirm the diagnosis of [[Cirrhosis|liver cirrhosis]]. | There have been recent advances towards newer imaging modalities to help detect and quantify [[hepatic]] [[fibrosis]] and [[cirrhosis]]. These investigations are comparable to the gold standard that is [[liver biopsy]] to confirm the diagnosis of [[Cirrhosis|liver cirrhosis]]. | ||
==Other Imaging Findings== | ==Other Imaging Findings== | ||
* More recent imaging techniques include:<ref name="pmid23891139">{{cite journal |vauthors=Piscaglia F, Marinelli S, Bota S, Serra C, Venerandi L, Leoni S, Salvatore V |title=The role of ultrasound elastographic techniques in chronic liver disease: current status and future perspectives |journal=Eur J Radiol |volume=83 |issue=3 |pages=450–5 |year=2014 |pmid=23891139 |doi=10.1016/j.ejrad.2013.06.009 |url=}}</ref><ref name="pmid22521355">{{cite journal |vauthors=Crespo G, Fernández-Varo G, Mariño Z, Casals G, Miquel R, Martínez SM, Gilabert R, Forns X, Jiménez W, Navasa M |title=ARFI, FibroScan, ELF, and their combinations in the assessment of liver fibrosis: a prospective study |journal=J. Hepatol. |volume=57 |issue=2 |pages=281–7 |year=2012 |pmid=22521355 |doi=10.1016/j.jhep.2012.03.016 |url=}}</ref> | * More recent imaging techniques include:<ref name="pmid23891139">{{cite journal |vauthors=Piscaglia F, Marinelli S, Bota S, Serra C, Venerandi L, Leoni S, Salvatore V |title=The role of ultrasound elastographic techniques in chronic liver disease: current status and future perspectives |journal=Eur J Radiol |volume=83 |issue=3 |pages=450–5 |year=2014 |pmid=23891139 |doi=10.1016/j.ejrad.2013.06.009 |url=}}</ref><ref name="pmid22521355">{{cite journal |vauthors=Crespo G, Fernández-Varo G, Mariño Z, Casals G, Miquel R, Martínez SM, Gilabert R, Forns X, Jiménez W, Navasa M |title=ARFI, FibroScan, ELF, and their combinations in the assessment of liver fibrosis: a prospective study |journal=J. Hepatol. |volume=57 |issue=2 |pages=281–7 |year=2012 |pmid=22521355 |doi=10.1016/j.jhep.2012.03.016 |url=}}</ref> | ||
**Transient elastography ( | **Transient elastography (FibroScan) | ||
**Acoustic [[radiation]] force impulse | **Acoustic [[radiation]] force impulse | ||
**[[Magnetic resonance elastography]] | **[[Magnetic resonance elastography]] | ||
| Line 16: | Line 15: | ||
**Transmits and measures [[vibration]] (elastic shear wave) as it propagates through the [[liver]] | **Transmits and measures [[vibration]] (elastic shear wave) as it propagates through the [[liver]] | ||
**[[Velocity]] of the [[wave]] passing through the [[liver]] correlates directly with [[Tissue (biology)|tissue]] stiffness | **[[Velocity]] of the [[wave]] passing through the [[liver]] correlates directly with [[Tissue (biology)|tissue]] stiffness | ||
*Note:<ref name="pmid20180235">{{cite journal |vauthors=Mueller S, Millonig G, Sarovska L, Friedrich S, Reimann FM, Pritsch M, Eisele S, Stickel F, Longerich T, Schirmacher P, Seitz HK |title=Increased liver stiffness in alcoholic liver disease: differentiating fibrosis from steatohepatitis |journal=World J. Gastroenterol. |volume=16 |issue=8 |pages=966–72 |year=2010 |pmid=20180235 |pmc=2828601 |doi= |url=}}</ref> | *'''Note:''' [[Alcoholic]] [[steatohepatitis]] often coexists with [[fibrosis]], since these tests are based on measurement of [[liver]] stiffness, it is better to wait until [[AST]] is less than 100U/L during [[alcohol withdrawal]] in order to preserve the diagnostic accuracy of this test.<ref name="pmid20180235">{{cite journal |vauthors=Mueller S, Millonig G, Sarovska L, Friedrich S, Reimann FM, Pritsch M, Eisele S, Stickel F, Longerich T, Schirmacher P, Seitz HK |title=Increased liver stiffness in alcoholic liver disease: differentiating fibrosis from steatohepatitis |journal=World J. Gastroenterol. |volume=16 |issue=8 |pages=966–72 |year=2010 |pmid=20180235 |pmc=2828601 |doi= |url=}}</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | | ||
{{WS}} | |||
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[[Category:Surgery]] | |||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Hepatology]] | [[Category:Hepatology]] | ||
[[Category:Medicine]] | |||
[[Category:Radiology]] | |||
Latest revision as of 20:20, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]
Overview
There have been recent advances towards newer imaging modalities to help detect and quantify hepatic fibrosis and cirrhosis. These investigations are comparable to the gold standard that is liver biopsy to confirm the diagnosis of liver cirrhosis.
Other Imaging Findings
- More recent imaging techniques include:[1][2]
- Transient elastography (FibroScan)
- Acoustic radiation force impulse
- Magnetic resonance elastography
- The listed newer imaging techniques have the following characteristics:
- Note: Alcoholic steatohepatitis often coexists with fibrosis, since these tests are based on measurement of liver stiffness, it is better to wait until AST is less than 100U/L during alcohol withdrawal in order to preserve the diagnostic accuracy of this test.[3]
References
- ↑ Piscaglia F, Marinelli S, Bota S, Serra C, Venerandi L, Leoni S, Salvatore V (2014). "The role of ultrasound elastographic techniques in chronic liver disease: current status and future perspectives". Eur J Radiol. 83 (3): 450–5. doi:10.1016/j.ejrad.2013.06.009. PMID 23891139.
- ↑ Crespo G, Fernández-Varo G, Mariño Z, Casals G, Miquel R, Martínez SM, Gilabert R, Forns X, Jiménez W, Navasa M (2012). "ARFI, FibroScan, ELF, and their combinations in the assessment of liver fibrosis: a prospective study". J. Hepatol. 57 (2): 281–7. doi:10.1016/j.jhep.2012.03.016. PMID 22521355.
- ↑ Mueller S, Millonig G, Sarovska L, Friedrich S, Reimann FM, Pritsch M, Eisele S, Stickel F, Longerich T, Schirmacher P, Seitz HK (2010). "Increased liver stiffness in alcoholic liver disease: differentiating fibrosis from steatohepatitis". World J. Gastroenterol. 16 (8): 966–72. PMC 2828601. PMID 20180235.