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Latest revision as of 20:44, 29 July 2020
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Brucellosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Brucella On the Web |
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American Roentgen Ray Society Images of Brucella |
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B. abortus |
This page is about microbiologic aspects of the organism(s). For clinical aspects of the disease, see brucellosis.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Danitza Lukac, Vishal Devarkonda, M.B.B.S[2]
Overview
Human brucellosis is caused by four Brucellae species: B. abortus, B. canis, B. melitensis, and B. suis.[1]
Causes
- Brucella is a genus of gram-negative bacteria.[2]They are small (0.5 to 0.7 by 0.6 to 1.5 µm), non-motile and encapsulated coccobacilli.
Brucella species
Brucella species have been found primarily in mammals. [3] Brucellla species, with their host and degree of virulence is described below:[4]
| Species | Host | Human Virulence |
|---|---|---|
| B. melitensis | Goats, sheep, cattle, buffaloes, dogs and camels | ++++ |
| B. abortus | Cattle, buffaloes, bison, dogs, elk, and horses | ++/+++ |
| B. canis | Dogs | + |
| B. suis | Pigs and sheep | + |
| B. ovis | Sheep | - |
Tests to differentiate brucella species
Following tests may be used to differentiate between the different species of brucella.[5]
| Test | B. melitensis | B. abortus | B. suis | B. ovis | B. canis |
|---|---|---|---|---|---|
| Need to CO2 | - | + | - | + | - |
| Production of H2S | - | + | + | - | - |
| Growth on basic fushin 0.002% | + | + | - | + | - |
| Growth on thionin 0.004% | - | - | + | + | + |
| Growth on thionin 0.002% | + | - | + | + | + |
| Destroy with Tb phage | - | + | - | - | - |
References
- ↑ "WHO" (PDF).
- ↑ Ryan KJ, Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed. ed.). McGraw Hill. ISBN 0-8385-8529-9.
- ↑ Pappas G, Akritidis N, Bosilkovski M, Tsianos E (2005). "Brucellosis". N Engl J Med. 352 (22): 2325–36. doi:10.1056/NEJMra050570. PMID 15930423.
- ↑ "WHO" (PDF).
- ↑ "WHO" (PDF).