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=== Matrix-assisted laser desorption === | === Matrix-assisted laser desorption === | ||
* | * Matrix-assisted laser desorption is based on the detection of specific features of a [[Proteolysis|proteolytic]] degradation product which is a product of mycological infections or noninfectious diseases. | ||
* Dermatophytes are represented by [[Proteolysis|proteolytic]] [[degradation]] products of native [[proteins]]. | * Dermatophytes are represented by [[Proteolysis|proteolytic]] [[degradation]] products of native [[proteins]]. | ||
* The [[peptide]] patterns of affected samples are compared with those of known samples containing [[peptide]] spectra from skin disorders stored in an already existing database. | * The [[peptide]] patterns of affected samples are compared with those of known samples containing [[peptide]] spectra from skin disorders stored in an already existing database. | ||
* | * Matrix-assisted laser desorption is a time efficient process, as it enables simultaneous identification of up to 64 dermatophyte strains, with results coming back within 24 hours. | ||
=== Reflectance confocal microscopy === | === Reflectance confocal microscopy === | ||
* | * Reflectance confocal microscopy provides imaging of the [[Epidermis (skin)|epidermis]] and superficial [[dermis]] at a high resolution and can be used to detect [[cutaneous]] [[Fungus|fungi]] and [[parasitic]] infestations. | ||
* Branching [[fungal]] [[hyphae]] can be visualized over an [[erythematous]], annular, [[Scaling skin|scaly]] patch. | * Branching [[fungal]] [[hyphae]] can be visualized over an [[erythematous]], annular, [[Scaling skin|scaly]] patch. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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{{WikiDoc Sources}} | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Needs content]] | [[Category:Needs content]] | ||
Latest revision as of 21:18, 29 July 2020
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Dermatophytosis Microchapters |
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Diagnosis |
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Treatment |
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Dermatophytosis other diagnostic studies On the Web |
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American Roentgen Ray Society Images of Dermatophytosis other diagnostic studies |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
Most of the time, ringworm can be diagnosed by looking at the skin. Other diagnostic studies that can be used to diagnose dermatophytosis are matrix-assisted laser desorption ionization test and reflectance confocal microscopy.
Other Diagnostic Studies
Other diagnostic studies to confirm dermatophytosis may include:
Matrix-assisted laser desorption
- Matrix-assisted laser desorption is based on the detection of specific features of a proteolytic degradation product which is a product of mycological infections or noninfectious diseases.
- Dermatophytes are represented by proteolytic degradation products of native proteins.
- The peptide patterns of affected samples are compared with those of known samples containing peptide spectra from skin disorders stored in an already existing database.
- Matrix-assisted laser desorption is a time efficient process, as it enables simultaneous identification of up to 64 dermatophyte strains, with results coming back within 24 hours.
Reflectance confocal microscopy
- Reflectance confocal microscopy provides imaging of the epidermis and superficial dermis at a high resolution and can be used to detect cutaneous fungi and parasitic infestations.
- Branching fungal hyphae can be visualized over an erythematous, annular, scaly patch.