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| {{CMG}}; {{AE}} {{Sahar}} | | {{CMG}}; {{AE}} {{Sahar}} |
| ==Overview== | | ==Overview== |
| Gonadoblastoma mainly develops in the context of gonadal dysgenesis. common causes of gonadoblastoma are:[[Turner syndrome]], XY [[gonadal dysgenesis]], [[Frasier syndrome]], [[WAGR syndrome]], [[Swyer syndrome]], and [[9p partial monosomy]].
| | There are no established [[causes]] for gonadoblastoma. However, there are certain [[risk factors]] that predispose to increased [[risk]] of gonadoblastoma. |
| | |
| ==Causes== | | ==Causes== |
| ===Life-threatening Causes===
| | There are no established [[causes]] for gonadoblastoma. However, there are certain [[risk factors]] that predispose to increased [[risk]] of gonadoblastoma. For more information on [[risk factors]], [[Gonadoblastoma risk factors|click here]]. |
| *There are no life-threatening causes of gonadoblastoma, however complications resulting from coexisting dysgerminoma is possible.
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| ===Common Causes===
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| Common causes of [disease name] may include:<ref name="MilewiczMrozińska2016">{{cite journal|last1=Milewicz|first1=Tomasz|last2=Mrozińska|first2=Sandra|last3=Szczepański|first3=Wojciech|last4=Białas|first4=Magdalena|last5=Kiałka|first5=Marta|last6=Doroszewska|first6=Katarzyna|last7=Kabzińska-Turek|first7=Monika|last8=Wojtyś|first8=Andrzej|last9=Ludwin|first9=Artur|last10=Chmura|first10=Łukasz|title=Dysgerminoma and gonadoblastoma in the course of Swyer syndrome|journal=Polish Journal of Pathology|volume=4|year=2016|pages=411–414|issn=1233-9687|doi=10.5114/pjp.2016.65876}}</ref><ref name="QuinonezPark2013">{{cite journal|last1=Quinonez|first1=Shane C.|last2=Park|first2=John M.|last3=Rabah|first3=Raja|last4=Owens|first4=Kailey M.|last5=Yashar|first5=Beverly M.|last6=Glover|first6=Thomas W.|last7=Keegan|first7=Catherine E.|title=9p partial monosomy and disorders of sex development: Review and postulation of a pathogenetic mechanism|journal=American Journal of Medical Genetics Part A|volume=161|issue=8|year=2013|pages=1882–1896|issn=15524825|doi=10.1002/ajmg.a.36018}}</ref><ref name="urlYen & Jaffes Reproductive Endocrinology | ScienceDirect">{{cite web |url=https://www.sciencedirect.com/book/9781455727582/yen-and-jaffes-reproductive-endocrinology |title=Yen & Jaffe's Reproductive Endocrinology | ScienceDirect |format= |work= |accessdate=}}</ref><ref name="PatelPappas2013">{{cite journal|last1=Patel|first1=Payal R.|last2=Pappas|first2=John|last3=Arva|first3=Nicoleta C.|last4=Franklin|first4=Bonita|last5=Brar|first5=Preneet Cheema|title=Early presentation of bilateral gonadoblastomas in a Denys-Drash syndrome patient: a cautionary tale for prophylactic gonadectomy|journal=Journal of Pediatric Endocrinology and Metabolism|volume=26|issue=9-10|year=2013|issn=2191-0251|doi=10.1515/jpem-2012-0409}}</ref>
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| *[[Frasier syndrome]]
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| *[[WAGR syndrome]]
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| *[[Swyer syndrome]]
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| *[[9p partial monosomy]]
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| ===Less Common Causes===
| |
| Less common causes of [disease name] include:
| |
| *[Cause1]
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| *[Cause2]
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| *[Cause3]
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| ===Genetic Causes===
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| *[Disease name] is caused by a mutation in the [gene name] gene.
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| ===Causes by Organ System===
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| {|style="width:80%; height:100px" border="1"
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| |style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
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| |style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
| |
| |-
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| |bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
| |
| | '''Dental'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
| |
| |-bgcolor="LightSteelBlue"
| |
| | '''Dermatologic'''
| |
| |bgcolor="Beige"| No underlying causes
| |
| |-
| |
| |-bgcolor="LightSteelBlue"
| |
| | '''Drug Side Effect'''
| |
| |bgcolor="Beige"| No underlying causes
| |
| |-
| |
| |-bgcolor="LightSteelBlue"
| |
| | '''Ear Nose Throat'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
| |
| |-bgcolor="LightSteelBlue"
| |
| | '''Endocrine'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
| |
| |-bgcolor="LightSteelBlue"
| |
| | '''Environmental'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
| |
| |-bgcolor="LightSteelBlue"
| |
| | '''Gastroenterologic'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
| |
| |-bgcolor="LightSteelBlue"
| |
| | '''Genetic'''
| |
| |bgcolor="Beige"| No underlying causes
| |
| |-
| |
| |-bgcolor="LightSteelBlue"
| |
| | '''Hematologic'''
| |
| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
| |
| | '''Iatrogenic'''
| |
| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Infectious Disease'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
| |
| | '''Musculoskeletal/Orthopedic'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Neurologic'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Nutritional/Metabolic'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Obstetric/Gynecologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Oncologic'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Ophthalmologic'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Overdose/Toxicity'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Psychiatric'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Pulmonary'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Renal/Electrolyte'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Rheumatology/Immunology/Allergy'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Sexual'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Trauma'''
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| |bgcolor="Beige"| No underlying causes
| |
| |-
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| |-bgcolor="LightSteelBlue"
| |
| | '''Urologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Miscellaneous'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |}
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| ===Causes in Alphabetical Order===
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| List the causes of the disease in alphabetical order:
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| <div style="-moz-column-count:3; column-count:3;">
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| * Cause 1
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| * Cause 2
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| * Cause 3
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| * Cause 4
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| * Cause 5
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| * Cause 6
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| * Cause 7
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| * Cause 8
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| * Cause 9
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| * Cause 10
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| </div>
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|
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| ==References== | | ==References== |
| {{Reflist|2}} | | {{Reflist|2}} |
|
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| {{WH}}
| | [[Category:Medicine]] |
| {{WS}}
| | [[Category:Oncology]] |
| [[Category: (name of the system)]] | | [[Category:Gynecology]] |
| | [[Category:Up-To-Date]] |