Hashimoto's thyroiditis history and symptoms: Difference between revisions
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{{CMG}} {{AE}} {{MMF}} | {{CMG}} {{AE}} {{MMF}} | ||
==Overview== | ==Overview== | ||
The hallmark of [[Hashimoto's thyroiditis]] is [[hypothyroidism]]. A positive history of [[autoimmune diseases]] and certain drug use are suggestive of Hashimoto's thyroiditis. The most common symptoms of Hashimoto's thyroiditis include [[fatigue]], [[constipation]], and cold intolerance. | The hallmark of [[Hashimoto's thyroiditis]] is [[hypothyroidism]]. A positive history of [[autoimmune diseases]] and certain drug use are suggestive of Hashimoto's thyroiditis. The most common symptoms of [[Hashimoto's thyroiditis]] include [[fatigue]], [[constipation]], and cold intolerance. | ||
==History== | ==History== | ||
Patients with [[Hashimoto's thyroiditis]] usually have the history of other [[autoimmune diseases]] and family history of autoimmune diseases. Occasionally, there might be a history of certain drug use like [[interferon-alpha]] and [[monoclonal antibodies]]. | Patients with [[Hashimoto's thyroiditis]] usually have the history of other [[autoimmune diseases]] and family history of [[autoimmune diseases]]. Occasionally, there might be a history of certain drug use like [[interferon-alpha]] and [[monoclonal antibodies]]. | ||
==Symptoms== | ==Symptoms== | ||
In many cases, Hashimoto's thyroiditis usually results in [[hypothyroidism]], although, in its acute phase, it can cause a transient hyperthyroidism [[hyperthyroidism|thyrotoxic]] state known as hashitoxicosis. Hypothyroidism resulting from Hashimoto's thyroiditis can cause these symptoms: <ref>Ladenson P, Kim M. Thyroid. In: Goldman L and Ausiello D, eds. ''Goldman: Cecil Medicine''. 23rd ed. Philadelphia, Pa:Saunders; 2007:chap 244.</ref><ref name="pmid24434360">{{cite journal |vauthors=Caturegli P, De Remigis A, Rose NR |title=Hashimoto thyroiditis: clinical and diagnostic criteria |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=391–7 |year=2014 |pmid=24434360 |doi=10.1016/j.autrev.2014.01.007 |url=}}</ref> | In many cases, Hashimoto's thyroiditis usually results in [[hypothyroidism]], although, in its acute phase, it can cause a transient hyperthyroidism [[hyperthyroidism|thyrotoxic]] state known as hashitoxicosis. Hypothyroidism resulting from [[Hashimoto's thyroiditis]] can cause these symptoms:<ref>Ladenson P, Kim M. Thyroid. In: Goldman L and Ausiello D, eds. ''Goldman: Cecil Medicine''. 23rd ed. Philadelphia, Pa:Saunders; 2007:chap 244.</ref><ref name="pmid24434360">{{cite journal |vauthors=Caturegli P, De Remigis A, Rose NR |title=Hashimoto thyroiditis: clinical and diagnostic criteria |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=391–7 |year=2014 |pmid=24434360 |doi=10.1016/j.autrev.2014.01.007 |url=}}</ref><ref name="urlHashimoto’s Thyroiditis | American Thyroid Association">{{cite web |url=https://www.thyroid.org/hashimotos-thyroiditis/ |title=Hashimoto’s Thyroiditis | American Thyroid Association |format= |work= |accessdate=}}</ref> | ||
===Common Symptoms=== | |||
=== | *[[Fatigue]] | ||
*[[Weight gain]] | |||
*[[Constipation]] | |||
*[[Cold intolerance]] | |||
*[[Xeroderma|Dry skin]] | |||
*[[Depression]] | |||
*[[Muscle aches]] | |||
*Reduced [[Exercise tolerance test|exercise tolerance]] | |||
*[[Menorrhagia]] or [[metrorrhagia]] | |||
===Organ-based Symptoms=== | |||
There are several organs involved in the [[hypothyroidism]] associated with [[Hashimoto's thyroiditis]]. The manifestation of Hashimoto's thyroiditis is variable as a result of the extensive involvement of multiple organs. The organ-based manifestation are as follows: | |||
{| class="wikitable" | |||
!Location | |||
!Symptoms | |||
|- | |||
!General | |||
| | |||
* [[Fatigue]] | * [[Fatigue]] | ||
* [[Lethargy]] | * [[Lethargy]] | ||
| Line 19: | Line 35: | ||
* [[Migraine]]s | * [[Migraine]]s | ||
* Puffy face | * Puffy face | ||
|- | |||
!Localized symptoms | |||
| | |||
*Enlarged neck or presence of [[goiter]] | *Enlarged neck or presence of [[goiter]] | ||
*[[Dysphonia]] (from involvement of the [[recurrent laryngeal nerve]]) | *[[Dysphonia]] (from involvement of the [[recurrent laryngeal nerve]]) | ||
*[[Dyspnea]] (from the [[Tracheal compression|compression of the trachea]]) | *[[Dyspnea]] (from the [[Tracheal compression|compression of the trachea]]) | ||
*[[Dysphagia]] (from impingement upon the esophagus) | *[[Dysphagia]] (from [[Impingement Syndrome|impingement]] upon the esophagus) | ||
* Small or shrunken thyroid gland (late in the disease) | * Small or shrunken [[thyroid gland]] (late in the disease) | ||
|- | |||
!Gastrointestinal system | |||
| | |||
* [[Constipation]] | * [[Constipation]] | ||
|- | |||
!Skin and appendages | |||
| | |||
* [[Dry skin]] | * [[Dry skin]] | ||
* [[Hair loss]] | * [[Hair loss]] | ||
|- | |||
!Neuro-psychiatric system | |||
| | |||
* [[Depression]] | * [[Depression]] | ||
* Difficulty concentrating or thinking | * Difficulty concentrating or thinking | ||
| Line 38: | Line 60: | ||
* [[Memory loss]] | * [[Memory loss]] | ||
* [[Panic attack]]s | * [[Panic attack]]s | ||
|- | |||
!Reproductive system | |||
| | |||
* [[Infertility]] | * [[Infertility]] | ||
*[[Oligomenorrhea]] | *[[Oligomenorrhea]] | ||
*[[Menometrorrhagia]] | *[[Menometrorrhagia]] | ||
|- | |||
!Musculoskeletal | |||
| | |||
*[[Joint stiffness]] | *[[Joint stiffness]] | ||
*[[Muscle cramps]] | *[[Muscle cramps]] | ||
|} | |||
==References== | ==References== | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category: | | ||
[[Category:Medicine]] | |||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Up-To-Date]] | |||
Latest revision as of 21:58, 29 July 2020
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Hashimoto's thyroiditis Microchapters |
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Hashimoto's thyroiditis history and symptoms On the Web |
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American Roentgen Ray Society Images of Hashimoto's thyroiditis history and symptoms |
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Risk calculators and risk factors for Hashimoto's thyroiditis history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The hallmark of Hashimoto's thyroiditis is hypothyroidism. A positive history of autoimmune diseases and certain drug use are suggestive of Hashimoto's thyroiditis. The most common symptoms of Hashimoto's thyroiditis include fatigue, constipation, and cold intolerance.
History
Patients with Hashimoto's thyroiditis usually have the history of other autoimmune diseases and family history of autoimmune diseases. Occasionally, there might be a history of certain drug use like interferon-alpha and monoclonal antibodies.
Symptoms
In many cases, Hashimoto's thyroiditis usually results in hypothyroidism, although, in its acute phase, it can cause a transient hyperthyroidism thyrotoxic state known as hashitoxicosis. Hypothyroidism resulting from Hashimoto's thyroiditis can cause these symptoms:[1][2][3]
Common Symptoms
- Fatigue
- Weight gain
- Constipation
- Cold intolerance
- Dry skin
- Depression
- Muscle aches
- Reduced exercise tolerance
- Menorrhagia or metrorrhagia
Organ-based Symptoms
There are several organs involved in the hypothyroidism associated with Hashimoto's thyroiditis. The manifestation of Hashimoto's thyroiditis is variable as a result of the extensive involvement of multiple organs. The organ-based manifestation are as follows:
| Location | Symptoms |
|---|---|
| General |
|
| Localized symptoms |
|
| Gastrointestinal system | |
| Skin and appendages | |
| Neuro-psychiatric system |
|
| Reproductive system | |
| Musculoskeletal |
References
- ↑ Ladenson P, Kim M. Thyroid. In: Goldman L and Ausiello D, eds. Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa:Saunders; 2007:chap 244.
- ↑ Caturegli P, De Remigis A, Rose NR (2014). "Hashimoto thyroiditis: clinical and diagnostic criteria". Autoimmun Rev. 13 (4–5): 391–7. doi:10.1016/j.autrev.2014.01.007. PMID 24434360.
- ↑ "Hashimoto's Thyroiditis | American Thyroid Association".