Hashimoto's thyroiditis laboratory findings: Difference between revisions
Jump to navigation
Jump to search
m (Bot: Removing from Primary care) |
|||
| (10 intermediate revisions by one other user not shown) | |||
| Line 16: | Line 16: | ||
* [[thyroglobulin|Anti-thyroglobulin]] antibodies (anti-Tg) | * [[thyroglobulin|Anti-thyroglobulin]] antibodies (anti-Tg) | ||
* [[Antimicrosomal antibody|Anti-microsomal antibodies]] can help obtain an accurate diagnosis<ref>{{cite book |last1= Giannini |first1= AJ |authorlink1= |title= The Biological Foundations of Clinical Psychiatry |url= |year= 1986 |publisher= Medical Examination Publishing Company |location= New Hyde Park, NY |language= |isbn= 0-87488-449-7 |oclc= |doi= |id= |page= |pages= 193–198 |quote= |ref= |bibcode= }}</ref> | * [[Antimicrosomal antibody|Anti-microsomal antibodies]] can help obtain an accurate diagnosis<ref>{{cite book |last1= Giannini |first1= AJ |authorlink1= |title= The Biological Foundations of Clinical Psychiatry |url= |year= 1986 |publisher= Medical Examination Publishing Company |location= New Hyde Park, NY |language= |isbn= 0-87488-449-7 |oclc= |doi= |id= |page= |pages= 193–198 |quote= |ref= |bibcode= }}</ref> | ||
===Diagnostic findings of Hashimoto's thyroiditis=== | |||
{| class="wikitable" | |||
| rowspan="2" |[[Thyroid function test]] | |||
|'''''↓'''''[[TSH]] '''↑''' [[T3]] and [[T4]] | |||
|In transient hyperthyroidism | |||
|- | |||
|'''↑''' [[TSH]] '''''↓''''' [[T3]] and [[T4]] | |||
|In the hypothyroid state | |||
|- | |||
| rowspan="3" |Antibodies | |||
|[[thyroid peroxidase|Anti-thyroid peroxidase]] antibodies | |||
|Positive | |||
|- | |||
|[[thyroglobulin|Anti-thyroglobulin]] antibodies | |||
|Positive | |||
|- | |||
|[[Antimicrosomal antibody|Anti-microsomal antibodies]] | |||
|Positive | |||
|- | |||
|[[Radioiodine]] reuptake | |||
|[[I-123 thyroid imaging|I-123]] reuptake | |||
|'''''↓''''' | |||
|} | |||
==References== | ==References== | ||
| Line 24: | Line 46: | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category: | | ||
[[Category:Medicine]] | |||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Up-To-Date]] | |||
Latest revision as of 21:58, 29 July 2020
|
Hashimoto's thyroiditis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Hashimoto's thyroiditis laboratory findings On the Web |
|
American Roentgen Ray Society Images of Hashimoto's thyroiditis laboratory findings |
|
Risk calculators and risk factors for Hashimoto's thyroiditis laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
Laboratory findings consistent with the diagnosis of Hashimoto's thyroiditis usually include increased thyroid stimulating hormone, decreased free T3 and free T4, and anti-thyroid peroxidase antibodies.
Laboratory Findings
Laboratory findings consistent with the diagnosis of Hashimoto's thyroiditis usually include increased thyroid stimulating hormone, decreased free T3 and free T4, and Anti-thyroid peroxidase antibodies.[1][2]
Thyroid hormones
- Increased Thyroid-stimulating hormone (TSH)
- Decreased Free T3 and Free T4
- TSH may be decreased in the transient hyperthyroid state[3]
Thyroid antibodies
- Anti-thyroid peroxidase antibodies (anti-TPO) (correlates with the disease severity)
- Anti-thyroglobulin antibodies (anti-Tg)
- Anti-microsomal antibodies can help obtain an accurate diagnosis[4]
Diagnostic findings of Hashimoto's thyroiditis
| Thyroid function test | ↓TSH ↑ T3 and T4 | In transient hyperthyroidism |
| ↑ TSH ↓ T3 and T4 | In the hypothyroid state | |
| Antibodies | Anti-thyroid peroxidase antibodies | Positive |
| Anti-thyroglobulin antibodies | Positive | |
| Anti-microsomal antibodies | Positive | |
| Radioiodine reuptake | I-123 reuptake | ↓ |
References
- ↑ Dong YH, Fu DG (2014). "Autoimmune thyroid disease: mechanism, genetics and current knowledge". Eur Rev Med Pharmacol Sci. 18 (23): 3611–8. PMID 25535130.
- ↑ Caturegli P, De Remigis A, Rose NR (2014). "Hashimoto thyroiditis: clinical and diagnostic criteria". Autoimmun Rev. 13 (4–5): 391–7. doi:10.1016/j.autrev.2014.01.007. PMID 24434360.
- ↑ Simmons, PJ (1998). "Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1beta and interleukin-6". Endocrinology. 139 (7): 3158–3186. doi:10.1210/en.139.7.3148. PMID 9645688.
- ↑ Giannini, AJ (1986). The Biological Foundations of Clinical Psychiatry. New Hyde Park, NY: Medical Examination Publishing Company. pp. 193–198. ISBN 0-87488-449-7.