Hepatitis D ultrasound: Difference between revisions
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==Overview== | ==Overview== | ||
The [[ultrasound]] may | The liver [[ultrasound]] of a patient with hepatitis D may reveal unspecific findings, such as: [[hepatomegaly]], [[gallbladder]] wall thickening, increased echogenicity, and signs of [[portal hypertension]]. It may also be used in the [[diagnosis]] and monitoring of [[hepatic cirrhosis]], as well as for [[hepatocellular carcinoma]]. Attending to the simultaneous occurrence of [[HDV]] and [[HBV]], [[HBsAg]] carriers with [[cirrhosis]] should be [[ultrasound|echographically]] evaluated every 6 months.<ref name=WHO1>{{cite web | title = Hepatitis D | url = http://www.who.int/csr/disease/hepatitis/HepatitisD_whocdscsrncs2001_1.pdf }}</ref> | ||
==Ultrasound== | ==Ultrasound== | ||
Although unspecific, the following findings may be identified in patients with [[hepatitis D]]:<ref name=WHO1>{{cite web | title = Hepatitis D | url = http://www.who.int/csr/disease/hepatitis/HepatitisD_whocdscsrncs2001_1.pdf }}</ref><ref name="pmid1544561">{{cite journal| author=Ferral H, Male R, Cardiel M, Munoz L, Quiroz y Ferrari F| title=Cirrhosis: diagnosis by liver surface analysis with high-frequency ultrasound. | journal=Gastrointest Radiol | year= 1992 | volume= 17 | issue= 1 | pages= 74-8 | pmid=1544561 | doi=10.1007/BF01888512 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1544561 }} </ref><ref name="pmid10499467">{{cite journal| author=Kok T, van der Jagt EJ, Haagsma EB, Bijleveld CM, Jansen PL, Boeve WJ| title=The value of Doppler ultrasound in cirrhosis and portal hypertension. | journal=Scand J Gastroenterol Suppl | year= 1999 | volume= 230 | issue= | pages= 82-8 | pmid=10499467 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10499467 }} </ref><ref name="pmid12216750">{{cite journal| author=Tchelepi H, Ralls PW, Radin R, Grant E| title=Sonography of diffuse liver disease. | journal=J Ultrasound Med | year= 2002 | volume= 21 | issue= 9 | pages= 1023-32; quiz 1033-4 | pmid=12216750 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12216750 }} </ref> | |||
* | *[[Hepatomegaly]] (acute phase) | ||
*Segmental [[hypertrophy]] with nodular appearance of [[liver]] | *Irregular thickening of the [[gallbladder]] wall, often due to [[inflammation]] and [[edema]] (more frequent in hepatitis A) | ||
*Increased [[echogenicity]] | |||
*Segmental [[hypertrophy]] with nodular appearance of the [[liver]] | |||
*[[Portal hypertension]]: | *[[Portal hypertension]]: | ||
:*[[Splenomegaly]] | :*[[Splenomegaly]] | ||
:*[[Ascites]] | :*[[Ascites]] | ||
:*[[Pleural effusion]] | :*[[Pleural effusion]] | ||
:*Reversed flow | |||
[[ | In advanced stages of the disease, in which [[cirrhosis]] might be present, the following findings may be identified: | ||
*[[Liver]] shape abnormalities | |||
*Parenchymal heterogeneity | |||
*Nodularity of [[liver]] surface | |||
[[HBsAg]] carriers should have regular | [[HBsAg]] carriers should have regular determinations of [[serum]] [[alpha-fetoprotein]]. [[Ultrasound]] examinations should be performed in patients above 40 years of age (with 6 month intervals). These tests should be repeated regularly in all patients who are [[HBsAg]] positive, with [[cirrhosis]].<ref name=WHO1>{{cite web | title = Hepatitis B | url = http://www.who.int/csr/disease/hepatitis/whocdscsrlyo20022/en/index3.html }}</ref> | ||
[[Ultrasound]] is also useful for the [[diagnosis]] and monitoring of [[hepatocellular carcinoma]], a potential [[complication]] of [[hepatitis D]]. | |||
== References == | == References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Hepatitis|D]] | [[Category:Hepatitis|D]] | ||
[[Category:Viruses]] | [[Category:Viruses]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Emergency mdicine]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Infectious disease]] | |||
[[Category:Hepatology]] | |||
Latest revision as of 22:06, 29 July 2020
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Hepatitis D |
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Diagnosis |
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Treatment |
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Hepatitis D ultrasound On the Web |
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American Roentgen Ray Society Images of Hepatitis D ultrasound |
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Risk calculators and risk factors for Hepatitis D ultrasound |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]; João André Alves Silva, M.D. [3] Jolanta Marszalek, M.D. [4]
Overview
The liver ultrasound of a patient with hepatitis D may reveal unspecific findings, such as: hepatomegaly, gallbladder wall thickening, increased echogenicity, and signs of portal hypertension. It may also be used in the diagnosis and monitoring of hepatic cirrhosis, as well as for hepatocellular carcinoma. Attending to the simultaneous occurrence of HDV and HBV, HBsAg carriers with cirrhosis should be echographically evaluated every 6 months.[1]
Ultrasound
Although unspecific, the following findings may be identified in patients with hepatitis D:[1][2][3][4]
- Hepatomegaly (acute phase)
- Irregular thickening of the gallbladder wall, often due to inflammation and edema (more frequent in hepatitis A)
- Increased echogenicity
- Segmental hypertrophy with nodular appearance of the liver
- Portal hypertension:
- Splenomegaly
- Ascites
- Pleural effusion
- Reversed flow
In advanced stages of the disease, in which cirrhosis might be present, the following findings may be identified:
HBsAg carriers should have regular determinations of serum alpha-fetoprotein. Ultrasound examinations should be performed in patients above 40 years of age (with 6 month intervals). These tests should be repeated regularly in all patients who are HBsAg positive, with cirrhosis.[1]
Ultrasound is also useful for the diagnosis and monitoring of hepatocellular carcinoma, a potential complication of hepatitis D.
References
- ↑ 1.0 1.1 1.2 "Hepatitis D" (PDF).
- ↑ Ferral H, Male R, Cardiel M, Munoz L, Quiroz y Ferrari F (1992). "Cirrhosis: diagnosis by liver surface analysis with high-frequency ultrasound". Gastrointest Radiol. 17 (1): 74–8. doi:10.1007/BF01888512. PMID 1544561.
- ↑ Kok T, van der Jagt EJ, Haagsma EB, Bijleveld CM, Jansen PL, Boeve WJ (1999). "The value of Doppler ultrasound in cirrhosis and portal hypertension". Scand J Gastroenterol Suppl. 230: 82–8. PMID 10499467.
- ↑ Tchelepi H, Ralls PW, Radin R, Grant E (2002). "Sonography of diffuse liver disease". J Ultrasound Med. 21 (9): 1023–32, quiz 1033-4. PMID 12216750.