Hepatitis E history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
Acute [[HEV infection]] is often [[asymptomatic]]. When present, [[symptoms]] develop 3 to 8 weeks after exposure to the [[HEV|virus]] and may include: [[muscle pain|muscle]] and [[joint pain]], [[weakness]], [[abdominal pain]], [[nausea]] and [[vomiting]], [[jaundice|yellowish discoloration of the eyes and skin]], [[Acholic stools|clay-colored bowel movements]], and dark-colored urine. | |||
==History | ==History and Symptoms== | ||
Most patients with hepatitis E, especially children with the disease, are [[asymptomatic]]. If [[symptoms]] occur, the average time is 3 to 8 weeks after exposure, with an average of 40 days. For patients with [[symptomatic]] disease, common [[symptoms]] may include:<ref name="pmid22549046">{{cite journal| author=Kamar N, Bendall R, Legrand-Abravanel F, Xia NS, Ijaz S, Izopet J et al.| title=Hepatitis E. | journal=Lancet | year= 2012 | volume= 379 | issue= 9835 | pages= 2477-88 | pmid=22549046 | doi=10.1016/S0140-6736(11)61849-7 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22549046 }} </ref><ref>{{cite journal |author=Chau TN, Lai ST, Tse C, ''et al'' |title=Epidemiology and clinical features of sporadic hepatitis E as compared with hepatitis A |journal=Am. J. Gastroenterol. |volume=101 |issue=2 |pages=292-6 |year=2006 |pmid=16454833 |doi=10.1111/j.1572-0241.2006.00416.x}}</ref><ref name="pmid22537448">{{cite journal| author=Wedemeyer H, Pischke S, Manns MP| title=Pathogenesis and treatment of hepatitis e virus infection. | journal=Gastroenterology | year= 2012 | volume= 142 | issue= 6 | pages= 1388-1397.e1 | pmid=22537448 | doi=10.1053/j.gastro.2012.02.014 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22537448 }} </ref> | |||
*[[Muscle pain]] | *[[Muscle pain]] | ||
*[[Joint pain]] | |||
*[[Muscle weakness]] | *[[Muscle weakness]] | ||
*[[Nausea]] | *[[Nausea]] | ||
*[[Vomiting]] | *[[Vomiting]] | ||
*[[Jaundice|Yellowish discoloration of the eyes and skin]] | |||
*[[Itching]] | *[[Itching]] | ||
*[[Acholic stools|Clay-colored bowel movements]] | |||
*Dark-colored urine | |||
*Prolonged [[cholestasis]] (60% patients) | |||
*[[Malaise]] | *[[Malaise]] | ||
*[[Anorexia|Lack of appetite]] | *[[Anorexia|Lack of appetite]] | ||
*[[Abdominal pain]] | *[[Abdominal pain]] | ||
*[[Diarrhea]] | *[[Diarrhea]] | ||
*Skin [[rash]] | |||
*[[ | |||
==References== | ==References== | ||
| Line 29: | Line 29: | ||
[[Category:Hepatitis|E]] | [[Category:Hepatitis|E]] | ||
[[Category:Viruses]] | [[Category:Viruses]] | ||
[[Category:Gastroenterology]] | |||
[[Category:Emergency mdicine]] | |||
[[Category:Disease]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
[[Category: | [[Category:Hepatology]] | ||
Latest revision as of 22:07, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
Acute HEV infection is often asymptomatic. When present, symptoms develop 3 to 8 weeks after exposure to the virus and may include: muscle and joint pain, weakness, abdominal pain, nausea and vomiting, yellowish discoloration of the eyes and skin, clay-colored bowel movements, and dark-colored urine.
History and Symptoms
Most patients with hepatitis E, especially children with the disease, are asymptomatic. If symptoms occur, the average time is 3 to 8 weeks after exposure, with an average of 40 days. For patients with symptomatic disease, common symptoms may include:[1][2][3]
- Muscle pain
- Joint pain
- Muscle weakness
- Nausea
- Vomiting
- Yellowish discoloration of the eyes and skin
- Itching
- Clay-colored bowel movements
- Dark-colored urine
- Prolonged cholestasis (60% patients)
- Malaise
- Lack of appetite
- Abdominal pain
- Diarrhea
- Skin rash
References
- ↑ Kamar N, Bendall R, Legrand-Abravanel F, Xia NS, Ijaz S, Izopet J; et al. (2012). "Hepatitis E." Lancet. 379 (9835): 2477–88. doi:10.1016/S0140-6736(11)61849-7. PMID 22549046.
- ↑ Chau TN, Lai ST, Tse C; et al. (2006). "Epidemiology and clinical features of sporadic hepatitis E as compared with hepatitis A". Am. J. Gastroenterol. 101 (2): 292–6. doi:10.1111/j.1572-0241.2006.00416.x. PMID 16454833.
- ↑ Wedemeyer H, Pischke S, Manns MP (2012). "Pathogenesis and treatment of hepatitis e virus infection". Gastroenterology. 142 (6): 1388–1397.e1. doi:10.1053/j.gastro.2012.02.014. PMID 22537448.