Large-sized vessel vasculitis with arthralgia: Difference between revisions
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Created page with "__NOTOC__ {{CMG}}; {{AE}} {{EG}} <span style="font-size:85%">'''Abbreviations:''' ABG= Arterial blood gas, ANA= Antinuclear antibody, ANP= Atrial natriuretic pepti..." |
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<span style="font-size:85%">'''Abbreviations:''' | <span style="font-size:85%">'''Abbreviations:''' | ||
ABG= [[Arterial blood gas]], ANA= [[Antinuclear antibody]], ANP= [[Atrial natriuretic peptide]], ASO= [[Antistreptolysin O|Antistreptolysin O antibody]], BNP= [[Brain natriuretic peptide]], CBC= [[Complete blood count]], COPD= [[Chronic obstructive pulmonary disease]], CRP= [[C-reactive protein]], CT= [[Computed tomography]], CXR= [[Chest X-ray]], DVT= [[Deep vein thrombosis]], ESR= [[Erythrocyte sedimentation rate]], HRCT= [[High Resolution CT]], IgE= [[Immunoglobulin E]], LDH= [[Lactate dehydrogenase]], PCWP= [[Pulmonary capillary wedge pressure]], PCR= [[Polymerase chain reaction]], PFT= [[Pulmonary function test]].</span> | ABG= [[Arterial blood gas]], ANA= [[Antinuclear antibody]], ANP= [[Atrial natriuretic peptide]], ASO= [[Antistreptolysin O|Antistreptolysin O antibody]], BNP= [[Brain natriuretic peptide]], CBC= [[Complete blood count]], COPD= [[Chronic obstructive pulmonary disease]], CRP= [[C-reactive protein]], CT= [[Computed tomography]], CXR= [[Chest X-ray]], DVT= [[Deep vein thrombosis]], ESR= [[Erythrocyte sedimentation rate]], HRCT= [[High Resolution CT]], IgE= [[Immunoglobulin E]], LDH= [[Lactate dehydrogenase]], PCWP= [[Pulmonary capillary wedge pressure]], PCR= [[Polymerase chain reaction]], PFT= [[Pulmonary function test]].</span> | ||
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{| style="border: 0px; font-size: 90%; margin: 3px;" align="center" | {| style="border: 0px; font-size: 90%; margin: 3px;" align="center" | ||
! colspan="3" rowspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" |Diseases | ! colspan="3" rowspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" |Diseases | ||
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! style="background:#4479BA; color: #FFFFFF;" align="center" |Other | ! style="background:#4479BA; color: #FFFFFF;" align="center" |Other | ||
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! rowspan=" | ! rowspan="5" style="padding: 5px 5px; background: #DCDCDC;" align="center" |Large-Vessel Vasculitis | ||
! colspan="2" style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Giant cell arteritis]]<ref name="pmid13679546">{{cite journal| author=Calvo-Romero JM| title=Giant cell arteritis. | journal=Postgrad Med J | year= 2003 | volume= 79 | issue= 935 | pages= 511-5 | pmid=13679546 | doi= | pmc=1742823 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13679546 }}</ref> | ! colspan="2" style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Giant cell arteritis]]<ref name="pmid13679546">{{cite journal| author=Calvo-Romero JM| title=Giant cell arteritis. | journal=Postgrad Med J | year= 2003 | volume= 79 | issue= 935 | pages= 511-5 | pmid=13679546 | doi= | pmc=1742823 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13679546 }}</ref> | ||
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! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Biopsy]] | ! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Biopsy]] | ||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Jaw pain]] and [[Jaw claudication|claudication]] | ! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Jaw pain]] and [[Jaw claudication|claudication]] | ||
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! rowspan="4" style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Systemic disease]] | ! rowspan="4" style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Systemic disease]] | ||
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==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Medicine]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Rheumatology]] | |||
Latest revision as of 22:28, 29 July 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]
Abbreviations: ABG= Arterial blood gas, ANA= Antinuclear antibody, ANP= Atrial natriuretic peptide, ASO= Antistreptolysin O antibody, BNP= Brain natriuretic peptide, CBC= Complete blood count, COPD= Chronic obstructive pulmonary disease, CRP= C-reactive protein, CT= Computed tomography, CXR= Chest X-ray, DVT= Deep vein thrombosis, ESR= Erythrocyte sedimentation rate, HRCT= High Resolution CT, IgE= Immunoglobulin E, LDH= Lactate dehydrogenase, PCWP= Pulmonary capillary wedge pressure, PCR= Polymerase chain reaction, PFT= Pulmonary function test.
| Diseases | Clinical manifestations | Para-clinical findings | Gold standard | Additional findings | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Symptoms | Physical examination | ||||||||||||||||||||
| Lab Findings | Imaging | Histopathology | |||||||||||||||||||
| Headache | Fever | Weight loss | Arthralgia | Claudication | Bruit | HTN | Focal neurological disorder | Biomarker | CBC | ESR | Other | CT scan | Angiography | Ultrasound/ Echocardiography | Other | ||||||
| Large-Vessel Vasculitis | Giant cell arteritis[1] | + | - | + | +/- | - | - | - | +/- | Pentraxin 3 (PTX3) | Normal | ↑ | ↑CRP | Stenosis, Occlusion, Dilatation | Aneurysm | - | Mural inflammation in MRA | Granulomatous inflammation of arteries | Biopsy | Jaw pain and claudication | |
| Systemic disease | Fibromuscular dysplasia[2] | + | - | +/- | + | + | + | + | +/- | Transforming growth factor β (TGF-β) | Normal | ↑ | ↑ Cr or BUN | Alternating stenosis and dilatations in CT angiography | Stenosis in the renal arteries | Luminal narrowing alternating with dilatation (Beads sign) | Focal concentric, long-segment tubular stenosis or outpouching in MRA | Fibrodysplastic changes, Collagen deposition | Digital subtraction angiography (DSA) | Spontaneous coronary artery dissection (SCAD) | |
| Ehlers-Danlos syndrome[3] | - | - | - | + | +/- | +/- | - | +/- | TGF-β | Normal | Normal | Cultured skin fibroblasts | Multiple vascular segments with aneurysms and dissections | Dissection of the posterolateral branch of the left circumflex coronary artery (LCx) | Visceral arteries abnormality | Vascular abnormalities in MRA | Thin and rare collagen bundles in the dermis | History and physical examination | Bleeding, Bruisability, Heart murmur | ||
| Polymyalgia rheumatica (PMR)[4] | + | - | +/- | + | - | - | - | - | Plasma fibrinogen | Normocytic, normochromic anemia | ↑ | CRP | Periodontoid localization of calcification | Vessel wall thickening, Increased mural contrast enhancement | Subacromial or subdeltoid bursitis | High F-FDG accumulation around the joints in FDG PET-CT | Small angular fibers, Pyknotic nuclear clumps, or target-targetoid fibers | - | Joint stiffness, Fatigue | ||
| Amyloidosis[5] | +/- | - | - | +/- | +/- | - | + | + | Immunoglobulin light chain(Amyloid) | Anemia | Normal | ↑ Cr or BUN, | Diffusely hypoattenuating and enlarged liver | Amyloid deposition in the media and adventitia of small arteries | Solid organs increased echogenicity | Tc-DPD for cardiac amyloid deposits | Extracellular deposition of fibrillar proteins | Biopsy | Cardiomegaly, Dyspnea | ||
References
- ↑ Calvo-Romero JM (2003). "Giant cell arteritis". Postgrad Med J. 79 (935): 511–5. PMC 1742823. PMID 13679546.
- ↑ Plouin PF, Perdu J, La Batide-Alanore A, Boutouyrie P, Gimenez-Roqueplo AP, Jeunemaitre X (2007). "Fibromuscular dysplasia". Orphanet J Rare Dis. 2: 28. doi:10.1186/1750-1172-2-28. PMC 1899482. PMID 17555581.
- ↑ Gazit Y, Jacob G, Grahame R (2016). "Ehlers-Danlos Syndrome-Hypermobility Type: A Much Neglected Multisystemic Disorder". Rambam Maimonides Med J. 7 (4). doi:10.5041/RMMJ.10261. PMC 5101008. PMID 27824552.
- ↑ Michet CJ, Matteson EL (2008). "Polymyalgia rheumatica". BMJ. 336 (7647): 765–9. doi:10.1136/bmj.39514.653588.80. PMC 2287267. PMID 18390527.
- ↑ Baker KR, Rice L (2012). "The amyloidoses: clinical features, diagnosis and treatment". Methodist Debakey Cardiovasc J. 8 (3): 3–7. PMC 3487569. PMID 23227278.