Multiple myeloma MRI: Difference between revisions

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__NOTOC__
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{{Multiple myeloma}}
{{Multiple myeloma}}
{{CMG}} {{AE}}{{HL}}
{{CMG}} {{AE}} {{HMHJ}}; {{HL}}; {{shyam}}


==Overview==
==Overview==
MRI may be diagnostic of multiple myeloma. Findings on MRI suggestive of multiple myeloma include infiltration and replacement of the bone marrow.<ref name="radio">Multiple myeloma. Radiopaedia(2015) http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref>
[[MRI]] may be [[Diagnosis|diagnostic]] of [[multiple myeloma]].<ref name="pmid27476706">{{cite journal |vauthors=Gerecke C, Fuhrmann S, Strifler S, Schmidt-Hieber M, Einsele H, Knop S |title=The Diagnosis and Treatment of Multiple Myeloma |journal=Dtsch Arztebl Int |volume=113 |issue=27-28 |pages=470–6 |date=July 2016 |pmid=27476706 |pmc=4973001 |doi=10.3238/arztebl.2016.0470 |url=}}</ref>Findings on [[MRI]] suggestive of [[multiple myeloma]] include infiltration and replacement of the [[bone marrow]].<ref name="radio">Multiple myeloma. Radiopaedia(2015) http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref><ref name="pmid24614435">{{cite journal |vauthors=Reisenbuckler C |title=Multiple myeloma and diagnostic imaging |journal=Radiol Technol |volume=85 |issue=4 |pages=391–410; quiz 411–3 |date=2014 |pmid=24614435 |doi= |url=}}</ref> [[MRI]] is a more expensive test than an [[X-ray]].


==MRI==
==MRI==
*[[Magnetic resonance imaging]] (MRI) is more sensitive than simple X-ray in the detection of lytic lesions of multiple myeloma.<ref name="radio">Multiple myeloma. Radiopaedia(2015) http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref>
[[Magnetic resonance imaging]] (MRI) is more sensitive than simple X-ray in the detection of lytic lesions of multiple myeloma.<ref name="radio">Multiple myeloma. Radiopaedia(2015) http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref> The International Myeloma Working Group (IMWG) recently proposed revised imaging criteria for a diagnosis of multiple myeloma. The MRI criteria is the presence of greater than 1 focal lesion of at least 5mm in size. Of note, MRI is the most expensive of the imaging tests. X-rays may sometimes be a sufficient substitute for assessing for the presence of lytic lesions for patients who are symptomatic. However, X-rays carry a risk for radiation exposure, unlike MRI. Clinical judgment should be used when determining whether to order MRI or X-rays to assess for lytic lesions. MRI may supersede [[skeletal survey]], especially when vertebral disease is suspected.<ref name="radio">Multiple myeloma. Radiopaedia(2015) http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref>
*MRI may supersede [[skeletal survey]], especially when vertebral disease is suspected.<ref name="radio">Multiple myeloma. Radiopaedia(2015) http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref>
*Shown below is a series of MRI images of [[long bones]] involved in multiple myeloma.  ([http://www.radswiki.net Images courtesy of RadsWiki])
*Shown below is a series of MRI images of [[long bones]] involved in multiple myeloma.  ([http://www.radswiki.net Images courtesy of RadsWiki])


<gallery>
<gallery>
Image:Multiple_myeloma_MRI101.jpg|Multiple myeloma|<small>([http://www.radswiki.net Images courtesy of RadsWiki])</small>
Image:Multiple_myeloma_MRI101.jpg|Multiple myeloma|<small>([http://www.radswiki.net Images courtesy of RadsWiki])</small>
<Image:Multiple_myeloma_MRI102.jpg|Multiple myeloma
<Image:Multiple_myeloma_MRI102.jpg|Multiple myeloma|<small>([http://www.radswiki.net Images courtesy of RadsWiki</small>
Image:Multiple_myeloma_MRI103.jpg|Multiple myeloma
Image:Multiple_myeloma_MRI103.jpg|Multiple myeloma|<small>([http://www.radswiki.net Images courtesy of RadsWiki</small></gallery>
</gallery>


*Shown below is a series of MRI images in a multiple myeloma patient complaining of [[back pain]].
*Shown below is a series of MRI images in a multiple myeloma patient complaining of [[back pain]].
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Image:


Multiple-myeloma-101.jpg
Multiple-myeloma-101.jpg|<small>([http://www.radswiki.net Images courtesy of RadsWiki])</small>
 
Image:
Image:


Multiple-myeloma-102.jpg
Multiple-myeloma-102.jpg|<small>([http://www.radswiki.net Images courtesy of RadsWiki])</small>
 
</gallery>
</gallery>
==References==
==References==
{{Reflist|1}}
{{Reflist|2}}
 
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[[Category:Medicine]]
[[Category:Hematology]]
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[[Category:Types of cancer]]
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[[Category:Surgery]]

Latest revision as of 22:47, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Hannan Javed, M.D.[2]; Haytham Allaham, M.D. [3]; Shyam Patel [4]

Overview

MRI may be diagnostic of multiple myeloma.[1]Findings on MRI suggestive of multiple myeloma include infiltration and replacement of the bone marrow.[2][3] MRI is a more expensive test than an X-ray.

MRI

Magnetic resonance imaging (MRI) is more sensitive than simple X-ray in the detection of lytic lesions of multiple myeloma.[2] The International Myeloma Working Group (IMWG) recently proposed revised imaging criteria for a diagnosis of multiple myeloma. The MRI criteria is the presence of greater than 1 focal lesion of at least 5mm in size. Of note, MRI is the most expensive of the imaging tests. X-rays may sometimes be a sufficient substitute for assessing for the presence of lytic lesions for patients who are symptomatic. However, X-rays carry a risk for radiation exposure, unlike MRI. Clinical judgment should be used when determining whether to order MRI or X-rays to assess for lytic lesions. MRI may supersede skeletal survey, especially when vertebral disease is suspected.[2]

  • Shown below is a series of MRI images in a multiple myeloma patient complaining of back pain.

References

  1. Gerecke C, Fuhrmann S, Strifler S, Schmidt-Hieber M, Einsele H, Knop S (July 2016). "The Diagnosis and Treatment of Multiple Myeloma". Dtsch Arztebl Int. 113 (27–28): 470–6. doi:10.3238/arztebl.2016.0470. PMC 4973001. PMID 27476706.
  2. 2.0 2.1 2.2 Multiple myeloma. Radiopaedia(2015) http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
  3. Reisenbuckler C (2014). "Multiple myeloma and diagnostic imaging". Radiol Technol. 85 (4): 391–410, quiz 411–3. PMID 24614435.