Peptic ulcer history and symptoms: Difference between revisions
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{{CMG}}; {{AE}} :{{MKK}} | {{CMG}}; {{AE}} :{{MKK}} | ||
==Overview== | ==Overview== | ||
The hallmark of peptic ulcer disease is an episodic [[epigastric pain]] which cause awakening at night.A positive history of epigastric pain, use of drugs like [[NSAIDs|NSAID]]<nowiki/>s including aspirin which inhibit cyclooxygenase,use of antiplatelets ,steroids and family history of peptic ulcer disease is suggestive of peptic ulcer disease. The most common symptoms of peptic ulcer disease include episodic [[epigastric pain]], [[heartburn]], loss of appettite, [[gastroesophageal reflux]], waterbrash,hematemesis and melena. Less common symptoms of peptic ulcer disease include | The hallmark of [[peptic ulcer disease]] is an episodic [[epigastric pain]] which cause awakening at night. A positive history of [[epigastric pain]], use of drugs like [[NSAIDs|NSAID]]<nowiki/>s including [[aspirin]] which inhibit [[cyclooxygenase]], use of antiplatelets,[[steroids]] and [[family history]] of [[peptic ulcer disease]] is suggestive of [[peptic ulcer disease]]. The most common symptoms of peptic ulcer disease include episodic [[epigastric pain]], [[heartburn]], loss of appettite, [[gastroesophageal reflux]], waterbrash, [[hematemesis]] and [[melena]]. Less common symptoms of [[peptic ulcer disease]] include intolerance to fatty food. | ||
==History == | ==History == | ||
Obtaining the history is the most important aspect of making a [[diagnosis]] of peptic ulcer disease. It provides insight into the [[Causality|cause]], precipitating factors and associated [[comorbid]] conditions. | Obtaining the history is the most important aspect of making a [[diagnosis]] of [[peptic ulcer disease]]. It provides insight into the [[Causality|cause]], precipitating factors and associated [[comorbid]] conditions. | ||
===Past Medical History=== | ===Past Medical History=== | ||
*A history of [[epigastric pain]], [[dyspepsia]], or prior [[peptic ulcer]] may suggest the [[Diagnosis-related group|diagnosis]] of [[peptic ulcer disease]].<ref name="LaineSolomon2016">{{cite journal|last1=Laine|first1=Loren|last2=Solomon|first2=Caren G.|title=Upper Gastrointestinal Bleeding Due to a Peptic Ulcer|journal=New England Journal of Medicine|volume=374|issue=24|year=2016|pages=2367–2376|issn=0028-4793|doi=10.1056/NEJMcp1514257}}</ref> | *A history of [[epigastric pain]], [[dyspepsia]], or prior [[peptic ulcer]] may suggest the [[Diagnosis-related group|diagnosis]] of [[peptic ulcer disease]].<ref name="LaineSolomon2016">{{cite journal|last1=Laine|first1=Loren|last2=Solomon|first2=Caren G.|title=Upper Gastrointestinal Bleeding Due to a Peptic Ulcer|journal=New England Journal of Medicine|volume=374|issue=24|year=2016|pages=2367–2376|issn=0028-4793|doi=10.1056/NEJMcp1514257}}</ref><ref name="pmid17956071">{{cite journal| author=Ramakrishnan K, Salinas RC| title=Peptic ulcer disease. | journal=Am Fam Physician | year= 2007 | volume= 76 | issue= 7 | pages= 1005-12 | pmid=17956071 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17956071 }} </ref><ref name="pmid28798512">{{cite journal| author=Drini M| title=Peptic ulcer disease and non-steroidal anti-inflammatory drugs. | journal=Aust Prescr | year= 2017 | volume= 40 | issue= 3 | pages= 91-93 | pmid=28798512 | doi=10.18773/austprescr.2017.037 | pmc=5478398 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28798512 }} </ref> | ||
===Medication History=== | ===Medication History=== | ||
*Prior use of [[aspirin]] or [[Non-steroidal anti-inflammatory drug|nonsteroidal anti-inflammatory drugs]] (NSAIDs) is important because these patients have an increased risk of [[gastric ulcer]] and a fourfold risk of significant [[Gastrointestinal tract|GI]] [[bleeding]] compared with other patients | *Prior use of [[aspirin]] or [[Non-steroidal anti-inflammatory drug|nonsteroidal anti-inflammatory drugs]] (NSAIDs) is important because these patients have an increased risk of [[gastric ulcer]] and a fourfold risk of significant [[Gastrointestinal tract|GI]] [[bleeding]] compared with other patients<ref name="pmid5303551">{{cite journal |vauthors=Goulston K, Cooke AR |title=Alcohol, aspirin, and gastrointestinal bleeding |journal=Br Med J |volume=4 |issue=5632 |pages=664–5 |year=1968 |pmid=5303551 |pmc=1912769 |doi= |url=}}</ref> | ||
===Social History=== | ===Social History=== | ||
*Helicobacter pylori infection is more common in | *[[Helicobacter pylori infection]] is more common in [[low socioeconomic status]] and increased number of siblings<ref name="pmid18783514">{{cite journal |vauthors=Bruce MG, Maaroos HI |title=Epidemiology of Helicobacter pylori infection |journal=Helicobacter |volume=13 Suppl 1 |issue= |pages=1–6 |year=2008 |pmid=18783514 |doi=10.1111/j.1523-5378.2008.00631.x |url=}}</ref> | ||
*Alcoholics also frequently have [[peptic ulcers]] or [[gastritis]] | *[[Alcoholics]] also frequently have [[peptic ulcers]] or [[gastritis]]<ref name="pmid2226291">{{cite journal |vauthors=MacMath TL |title=Alcohol and gastrointestinal bleeding |journal=Emerg. Med. Clin. North Am. |volume=8 |issue=4 |pages=859–72 |year=1990 |pmid=2226291 |doi= |url=}}</ref><ref name="pmid5303551" /> | ||
*[[Cigarette smoke|Cigarette smokers]] have a significantly higher rate of the recurrent [[duodenal ulcer]] as compared with nonsmokers | *[[Cigarette smoke|Cigarette smokers]] have a significantly higher rate of the recurrent [[duodenal ulcer]] as compared with nonsmokers <ref name="pmid28839832">{{cite journal |vauthors=Jafar W, Jafar AJN, Sharma A |title=Upper gastrointestinal haemorrhage: an update |journal=Frontline Gastroenterol |volume=7 |issue=1 |pages=32–40 |year=2016 |pmid=28839832 |pmc=5369541 |doi=10.1136/flgastro-2014-100492 |url=}}</ref><ref name="pmid17942452">{{cite journal |vauthors=Palmer K |title=Acute upper gastrointestinal haemorrhage |journal=Br. Med. Bull. |volume=83 |issue= |pages=307–24 |year=2007 |pmid=17942452 |doi=10.1093/bmb/ldm023 |url=}}</ref> | ||
===Family History=== | ===Family History=== | ||
*Family history of peptic ulcer disease increases the risk of peptic ulcer | *Family history of [[peptic ulcer disease]] increases the risk of [[peptic ulcer]] | ||
*History of peptic ulcer disease in mother increases the risk of peptic ulcer disease in children | *History of [[peptic ulcer disease]] in mother increases the risk of [[peptic ulcer disease]] in [[children]] | ||
== Symptoms == | == Symptoms == | ||
*The majority of patients with the peptic ulcer disease are symptomatic but some people | *The majority of patients with the [[peptic ulcer disease]] are symptomatic but some people do not show any symptoms,called as a silent ulcer. | ||
*The hallmark of peptic ulcer disease : | *The hallmark of [[peptic ulcer disease]]: | ||
**Episodic gnawing or burning epigastric pain which occurs | **Episodic gnawing or burning [[epigastric pain]] which occurs one to five hours after meals or on an empty [[stomach]] | ||
**Nocturnal pain relieved by food intake, [[Antacid|antacids]], or | **Nocturnal [[pain]] relieved by [[food]] intake, [[Antacid|antacids]], or antisecretory agents<ref name="pmid17956071" /> | ||
**Chronic use of [[NSAIDs]] | **Chronic use of [[NSAIDs]] | ||
{| class="wikitable" | {| class="wikitable" | ||
! colspan="3" |Difference in symptoms of gastric and duodenal ulcer | ! colspan="3" |Difference in symptoms of gastric and duodenal ulcer | ||
| Line 35: | Line 35: | ||
|'''Duodenal ulcer''' | |'''Duodenal ulcer''' | ||
|- | |- | ||
| rowspan="3" |Epigastric pain | | rowspan="3" |[[Epigastric pain]] | ||
|Occurs 1-2 hours after eating | |Occurs 1-2 hours after eating | ||
|Occurs 2-5 hours after eating | |Occurs 2-5 hours after eating | ||
| Line 42: | Line 42: | ||
|Decreases with eating | |Decreases with eating | ||
|- | |- | ||
|Pain at night is less common | |[[Pain]] at night is less common | ||
|Pain at night is more common | |[[Pain]] at night is more common | ||
|- | |- | ||
|Heartburn, chest discomfort | |[[Heartburn]], [[chest discomfort]] | ||
and early satiety | and early [[satiety]] | ||
|Occurs commonly | |Occurs commonly | ||
|Less commonly occurs | |Less commonly occurs | ||
|- | |- | ||
|Bleeding presentation | |[[Bleeding]] presentation | ||
| | | | ||
* Melena | * [[Melena]] | ||
* Hematemesis | * [[Hematemesis]] | ||
| | | | ||
* Melena | * [[Melena]] | ||
* Hematochezia | * [[Hematochezia]] | ||
|} | |} | ||
===Common Symptoms=== | ===Common Symptoms=== | ||
Common symptoms of peptic ulcer disease include: | Common symptoms of [[peptic ulcer disease]] include: | ||
*Episodic [[epigastric pain]] | *Episodic [[epigastric pain]] | ||
*[[Heartburn]] | *[[Heartburn]] | ||
*[[ | *[[Bloating]] | ||
*[[Nausea and vomiting]] | |||
*Waterbrash | |||
*[[Indigestion]] | *[[Indigestion]] | ||
*[[Hematemesis]] | *[[Hematemesis]] | ||
*[[Melena]] | *[[Melena]] | ||
*[[Loss of appetite]] | |||
===Less Common Symptoms=== | ===Less Common Symptoms=== | ||
Less common symptoms of peptic ulcer disease include: | Less common symptoms of peptic ulcer disease include: | ||
*[[Intolerance to fatty food]] | *[[Intolerance to fatty food]] | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WikiDoc Help Menu}} | |||
{{WikiDoc Sources}} | |||
[[Category:Needs content]] | [[Category:Needs content]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Needs overview]] | [[Category:Needs overview]] | ||
Latest revision as of 23:37, 29 July 2020
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Guidelines for the Indications to Test for, and to Treat, H. pylori Infection |
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Guidelines to document H. pylori antimicrobial resistance in the North America |
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Peptic ulcer history and symptoms On the Web |
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Risk calculators and risk factors for Peptic ulcer history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: :Manpreet Kaur, MD [2]
Overview
The hallmark of peptic ulcer disease is an episodic epigastric pain which cause awakening at night. A positive history of epigastric pain, use of drugs like NSAIDs including aspirin which inhibit cyclooxygenase, use of antiplatelets,steroids and family history of peptic ulcer disease is suggestive of peptic ulcer disease. The most common symptoms of peptic ulcer disease include episodic epigastric pain, heartburn, loss of appettite, gastroesophageal reflux, waterbrash, hematemesis and melena. Less common symptoms of peptic ulcer disease include intolerance to fatty food.
History
Obtaining the history is the most important aspect of making a diagnosis of peptic ulcer disease. It provides insight into the cause, precipitating factors and associated comorbid conditions.
Past Medical History
- A history of epigastric pain, dyspepsia, or prior peptic ulcer may suggest the diagnosis of peptic ulcer disease.[1][2][3]
Medication History
- Prior use of aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) is important because these patients have an increased risk of gastric ulcer and a fourfold risk of significant GI bleeding compared with other patients[4]
Social History
- Helicobacter pylori infection is more common in low socioeconomic status and increased number of siblings[5]
- Alcoholics also frequently have peptic ulcers or gastritis[6][4]
- Cigarette smokers have a significantly higher rate of the recurrent duodenal ulcer as compared with nonsmokers [7][8]
Family History
- Family history of peptic ulcer disease increases the risk of peptic ulcer
- History of peptic ulcer disease in mother increases the risk of peptic ulcer disease in children
Symptoms
- The majority of patients with the peptic ulcer disease are symptomatic but some people do not show any symptoms,called as a silent ulcer.
- The hallmark of peptic ulcer disease:
| Difference in symptoms of gastric and duodenal ulcer | ||
|---|---|---|
| Gastric ulcer | Duodenal ulcer | |
| Epigastric pain | Occurs 1-2 hours after eating | Occurs 2-5 hours after eating |
| Increases with eating | Decreases with eating | |
| Pain at night is less common | Pain at night is more common | |
| Heartburn, chest discomfort
and early satiety |
Occurs commonly | Less commonly occurs |
| Bleeding presentation | ||
Common Symptoms
Common symptoms of peptic ulcer disease include:
- Episodic epigastric pain
- Heartburn
- Bloating
- Nausea and vomiting
- Waterbrash
- Indigestion
- Hematemesis
- Melena
- Loss of appetite
Less Common Symptoms
Less common symptoms of peptic ulcer disease include:
References
- ↑ Laine, Loren; Solomon, Caren G. (2016). "Upper Gastrointestinal Bleeding Due to a Peptic Ulcer". New England Journal of Medicine. 374 (24): 2367–2376. doi:10.1056/NEJMcp1514257. ISSN 0028-4793.
- ↑ 2.0 2.1 Ramakrishnan K, Salinas RC (2007). "Peptic ulcer disease". Am Fam Physician. 76 (7): 1005–12. PMID 17956071.
- ↑ Drini M (2017). "Peptic ulcer disease and non-steroidal anti-inflammatory drugs". Aust Prescr. 40 (3): 91–93. doi:10.18773/austprescr.2017.037. PMC 5478398. PMID 28798512.
- ↑ 4.0 4.1 Goulston K, Cooke AR (1968). "Alcohol, aspirin, and gastrointestinal bleeding". Br Med J. 4 (5632): 664–5. PMC 1912769. PMID 5303551.
- ↑ Bruce MG, Maaroos HI (2008). "Epidemiology of Helicobacter pylori infection". Helicobacter. 13 Suppl 1: 1–6. doi:10.1111/j.1523-5378.2008.00631.x. PMID 18783514.
- ↑ MacMath TL (1990). "Alcohol and gastrointestinal bleeding". Emerg. Med. Clin. North Am. 8 (4): 859–72. PMID 2226291.
- ↑ Jafar W, Jafar A, Sharma A (2016). "Upper gastrointestinal haemorrhage: an update". Frontline Gastroenterol. 7 (1): 32–40. doi:10.1136/flgastro-2014-100492. PMC 5369541. PMID 28839832. Vancouver style error: initials (help)
- ↑ Palmer K (2007). "Acute upper gastrointestinal haemorrhage". Br. Med. Bull. 83: 307–24. doi:10.1093/bmb/ldm023. PMID 17942452.