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{{Polycystic kidney disease}}
{{Polycystic kidney disease}}
{{CMG}} {{AE}} {{AN}}
{{CMG}}; {{AE}}{{MKA}}, [[User:Sergekorjian|Serge Korjian]],[[User:YazanDaaboul|Yazan Daaboul]]


==Overview==
==Overview==
The hallmark of polycystic kidney disease is [[flank]] or [[back]] [[pain]]. A positive family history of [[renal failure]], [[cystic]] [[diseases]], intracranial [[aneurysms]] is suggestive of polycystic kidney disease. The most common symptoms of polycystic kidney disease include [[hematuria]], [[polyuria]], [[nocturia]] and [[hypertension]].


==Symptoms==
==History and Symptoms==
*[[Abdominal pain]] or [[abdominal tenderness]]
*The hallmark of polycystic kidney disease is [[flank]] or [[back]] [[pain]]. A positive family history of [[renal failure]], [[cystic]] diseases, [[intracranial aneurysms]] is suggestive of polycystic kidney disease.
*[[Flank pain]]
*The most common symptoms of polycystic kidney disease include [[hematuria]], [[polyuria]], [[nocturia]] and [[hypertension]].
*[[Back pain]]
 
*[[Hematuria|Blood in urine]]:
===History===
**The cysts are unusually susceptible to rupture from injury, resulting in internal hemorrhage and [[retroperitoneal hematoma]]
Patients with polycystic kidney disease may have a positive history of:<ref name="pmid8321262">{{cite journal| author=Gabow PA| title=Autosomal dominant polycystic kidney disease. | journal=N Engl J Med | year= 1993 | volume= 329 | issue= 5 | pages= 332-42 | pmid=8321262 | doi=10.1056/NEJM199307293290508 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8321262 }} </ref>
*[[Nocturia|excessive urination at night]]
*[[Fatigue]]/[[weakness]]/[[malaise]]
===Other symptoms===
*[[Blood]] in [[urine]]
*[[Drowsiness]]
*[[Flank]]/[[back]] [[pain]]
*[[Joint pain]]
*[[Headache]] from [[hypertension]]
*Nail abnormalities
*Family history of [[renal failure]] or diagnosed [[renal]] [[cystic]] diseases
*Family history of intracranial or abdominal [[aortic]] [[aneurysms]]
 
===Common Symptoms===
Common symptoms of polycystic kidney disease include:<ref name="pmid17434405">{{cite journal| author=Torres VE, Harris PC, Pirson Y| title=Autosomal dominant polycystic kidney disease. | journal=Lancet | year= 2007 | volume= 369 | issue= 9569 | pages= 1287-301 | pmid=17434405 | doi=10.1016/S0140-6736(07)60601-1 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17434405 }} </ref>
*[[Flank]]/[[back]] [[pain]]
*[[Hematuria]]
*[[Hypertension]]
*[[Polyuria]]
*[[Nocturia]]
 
===Less Common Symptoms===
Less common symptoms of polycystic kidney disease include:<ref name="pmid26413277">{{cite journal |vauthors=Baker A, King D, Marsh J, Makin A, Carr A, Davis C, Kirby C |title=Understanding the physical and emotional impact of early-stage ADPKD: experiences and perspectives of patients and physicians |journal=Clin Kidney J |volume=8 |issue=5 |pages=531–7 |date=October 2015 |pmid=26413277 |pmc=4581379 |doi=10.1093/ckj/sfv060 |url=}}</ref>
*[[Dyspnea]]
*Early [[satiety]]
*[[Jaundice]]
*[[Urinary tract infection]]
*[[Pyelonephritis]]
*[[Nephrolithiasis]]


==References==
==References==
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[[Category:Up-To-Date]]
[[Category:Medicine]]
[[Category:Nephrology]]

Latest revision as of 23:46, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2], Serge Korjian,Yazan Daaboul

Overview

The hallmark of polycystic kidney disease is flank or back pain. A positive family history of renal failure, cystic diseases, intracranial aneurysms is suggestive of polycystic kidney disease. The most common symptoms of polycystic kidney disease include hematuria, polyuria, nocturia and hypertension.

History and Symptoms

History

Patients with polycystic kidney disease may have a positive history of:[1]

Common Symptoms

Common symptoms of polycystic kidney disease include:[2]

Less Common Symptoms

Less common symptoms of polycystic kidney disease include:[3]

References

  1. Gabow PA (1993). "Autosomal dominant polycystic kidney disease". N Engl J Med. 329 (5): 332–42. doi:10.1056/NEJM199307293290508. PMID 8321262.
  2. Torres VE, Harris PC, Pirson Y (2007). "Autosomal dominant polycystic kidney disease". Lancet. 369 (9569): 1287–301. doi:10.1016/S0140-6736(07)60601-1. PMID 17434405.
  3. Baker A, King D, Marsh J, Makin A, Carr A, Davis C, Kirby C (October 2015). "Understanding the physical and emotional impact of early-stage ADPKD: experiences and perspectives of patients and physicians". Clin Kidney J. 8 (5): 531–7. doi:10.1093/ckj/sfv060. PMC 4581379. PMID 26413277.

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