Renal oncocytoma biopsy: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Renal Oncocytoma}} | {{Renal Oncocytoma}} | ||
{{CMG}} | {{CMG}}; {{AE}} {{SC}} | ||
==Overview== | ==Overview== | ||
On [[biopsy]], renal oncocytoma is characterized by oncocytes and large [[eosinophilic]] cells. | |||
==Biopsy== | ==Biopsy== | ||
* On biopsy, renal oncocytoma is characterized by oncocytes and large [[eosinophilic]] cells. | * On biopsy, renal oncocytoma is characterized by oncocytes and large [[eosinophilic]] cells. | ||
* Biopsy is insufficient to distinguish renal oncocytoma from [[renal cell carcinoma]], therefore immunostaining may be required. | * Biopsy is insufficient to distinguish renal oncocytoma from [[renal cell carcinoma]], therefore immunostaining may be required.<ref name="pmid11748579">{{cite journal |vauthors=Liu J, Fanning CV |title=Can renal oncocytomas be distinguished from renal cell carcinoma on fine-needle aspiration specimens? A study of conventional smears in conjunction with ancillary studies |journal=[[Cancer]] |volume=93 |issue=6 |pages=390–7 |year=2001 |pmid=11748579 |doi= |url= |issn=}}</ref> | ||
* Immunohistochemical profile<ref>[Renal Neoplasms: An Update on Immunohistochemical and Histochemical Features http://www.dako.com/08066_12may10_webchapter26.pdf]</ref> | * [[Immunohistochemical]] profile<ref>[Renal Neoplasms: An Update on Immunohistochemical and Histochemical Features http://www.dako.com/08066_12may10_webchapter26.pdf]</ref> | ||
*[[Cytokeratin]] AE1/AE3 + | :* [[Cytokeratin]] AE1/AE3 + | ||
*[[Vimentin]] - | :* [[Vimentin]] - | ||
*Epithelial membrane antigen + | :* Epithelial membrane antigen + | ||
*[[CD10]]+/- | :* [[CD10]]+/- | ||
*CK7 +/- parcellaire | :* CK7 +/- parcellaire | ||
*CK20 - | :* CK20 - | ||
*CK19 - | :* CK19 - | ||
*[[AMACR]] ([[Racemase]]) - | :* [[AMACR]] ([[Racemase]]) - | ||
*S100 + | :* S100 + | ||
* | :* [[CD117]] + | ||
*Cadherin-E + | :* Cadherin-E + | ||
*[[TFE3]] - | :* [[TFE3]] - | ||
*CAM5.2 + | :* CAM5.2 + | ||
==References== | ==References== | ||
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{{WS}} | {{WS}} | ||
[[Category: | [[Category:Up-To-Date]] | ||
[[Category:Medicine]] | |||
[[Category:Oncology]] | |||
[[Category:Nephrology]] | |||
Latest revision as of 23:57, 29 July 2020
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Renal oncocytoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Renal oncocytoma biopsy On the Web |
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American Roentgen Ray Society Images of Renal oncocytoma biopsy |
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Risk calculators and risk factors for Renal oncocytoma biopsy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
On biopsy, renal oncocytoma is characterized by oncocytes and large eosinophilic cells.
Biopsy
- On biopsy, renal oncocytoma is characterized by oncocytes and large eosinophilic cells.
- Biopsy is insufficient to distinguish renal oncocytoma from renal cell carcinoma, therefore immunostaining may be required.[1]
- Immunohistochemical profile[2]
References
- ↑ Liu J, Fanning CV (2001). "Can renal oncocytomas be distinguished from renal cell carcinoma on fine-needle aspiration specimens? A study of conventional smears in conjunction with ancillary studies". Cancer. 93 (6): 390–7. PMID 11748579.
- ↑ [Renal Neoplasms: An Update on Immunohistochemical and Histochemical Features http://www.dako.com/08066_12may10_webchapter26.pdf]