Renal oncocytoma diagnostic study of choice: Difference between revisions

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__NOTOC__
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{{Renal oncocytoma}}
{{Renal Oncocytoma}}
{{CMG}}; {{AE}}{{Homa}}
{{CMG}}; {{AE}}{{HK}}
== Overview ==
== Overview ==
The [[Gold standard (test)|gold standard test]] for the [[diagnosis]] of renal oncoytoma is [[renal]] [[biopsy]] and [[Histopathology|histopathological]] charcarterization.


== Diagnostic Study of Choice ==
== Diagnostic Study of Choice ==
 
The [[Gold standard (test)|gold standard test]] for the [[diagnosis]] of renal oncoytoma is [[renal]] [[biopsy]] and [[Histopathology|histopathological]] charcarterization. [[Histologically]], renal oncocytomas exhibit nests and tubular structures lined by [[cells]] with [[eosinophilic]] [[cytoplasmic]] [[granularity]], [[Edema|edematous]] myxoid or hyalinized stroma.<ref name="pmid29090117">{{cite journal |vauthors=Wobker SE, Williamson SR |title=Modern Pathologic Diagnosis of Renal Oncocytoma |journal=J Kidney Cancer VHL |volume=4 |issue=4 |pages=1–12 |date=2017 |pmid=29090117 |pmc=5634396 |doi=10.15586/jkcvhl.2017.96 |url=}}</ref><ref name="pmid29299091">{{cite journal |vauthors=Smith CJ, Wang MX, Feely M, Otto B, Grajo JR |title=Oncocytoma: A Differential Consideration for an Incidentally Detected FDG-Avid Renal Mass on PET/CT |journal=J Radiol Case Rep |volume=11 |issue=5 |pages=27–33 |date=May 2017 |pmid=29299091 |pmc=5743137 |doi=10.3941/jrcr.v11i5.3117 |url=}}</ref><ref name="pmid16360437">{{cite journal |vauthors=Neuzillet Y, Lechevallier E, Andre M, Daniel L, Nahon O, Coulange C |title=Follow-up of renal oncocytoma diagnosed by percutaneous tumor biopsy |journal=Urology |volume=66 |issue=6 |pages=1181–5 |date=December 2005 |pmid=16360437 |doi=10.1016/j.urology.2005.06.001 |url=}}</ref>
=== Study of choice ===
[Name of the investigation] is the gold standard test for the diagnosis of [disease name].
 
OR
 
The following result of [gold standard test] is confirmatory of [disease name]:
* [Result 1]
* [Result 2]
 
OR
 
[Name of the investigation] must be performed when:
* The patient presents with [symptom/sign 1], [symptom/sign 2], and [symptom/sign 3].
* A [name of test] is positive for [sign 1], [sign 2], and [sign 3] in the patient.
 
OR
 
[Name of the investigation] is the gold standard test for the diagnosis of [disease name].
 
OR
 
The diagnostic study of choice for [disease name] is [name of the investigation].
 
OR
 
There is no single diagnostic study of choice for the diagnosis of [disease name].
 
OR
 
There is no single diagnostic study of choice for the diagnosis of [disease name], but [disease name] can be diagnosed based on [name of the investigation 1] and [name of the investigation 2].
 
OR
 
[Disease name] is primarily diagnosed based on the clinical presentation.
 
OR
 
Investigations:
* Among the patients who present with clinical signs of [disease name], the [investigation name] is the most specific test for the diagnosis.
* Among the patients who present with clinical signs of [disease name], the [investigation name] is the most sensitive test for diagnosis.
* Among the patients who present with clinical signs of [disease name], the [investigation name] is the most efficient test for diagnosis.
 
==== The comparison of various diagnostic studies for [disease name] ====
{|
|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
! style="background: #4479BA; color: #FFFFFF; text-align: center;" | Test
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Sensitivity
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Specificity
|-
! style="background: #696969; color: #FFFFFF; text-align: center;" |Test 1
| style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
| style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
|-
! style="background: #696969; color: #FFFFFF; text-align: center;" |Test 2
| style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
| style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
|}
<small> [Name of test with higher sensitivity and specificity] is the preferred investigation based on the sensitivity and specificity</small>
 
===== Diagnostic results =====
The following finding(s) on performing [investigation name] is(are) confirmatory for [disease name]:
* [Finding 1]
* [Finding 2]
 
===== Sequence of Diagnostic Studies =====
The [name of investigation] must be performed when:
* The patient presented with symptoms/signs 1, 2, and 3 as the first step of diagnosis.
* A positive [test] is detected in the patient, to confirm the diagnosis.
 
OR
 
The various investigations must be performed in the following order:
* [Initial investigation]
* [2nd investigation]
 
=== Name of Diagnostic Criteria ===
 
'''It is recommended that you include the criteria in a table. Make sure you always cite the source of the content and whether the table has been adapted from another source.'''
 
[Disease name] is primarily diagnosed based on clinical presentation. There are no established criteria for the diagnosis of [disease name].
 
OR
 
There is no single diagnostic study of choice for [disease name], though [disease name] may be diagnosed based on [name of criteria] established by [...].
 
OR
 
The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
 
OR
 
The diagnosis of [disease name] is based on the [criteria name] criteria, which includes [criterion 1], [criterion 2], and [criterion 3].
 
OR
 
[Disease name] may be diagnosed at any time if one or more of the following criteria are met:
* Criteria 1
* Criteria 2
* Criteria 3
 
OR
 
'''IF there are clear, established diagnostic criteria'''
 
The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
 
OR
 
The diagnosis of [disease name] is based on the [criteria name] criteria, which include [criterion 1], [criterion 2], and [criterion 3].
 
OR
 
The diagnosis of [disease name] is based on the [definition name] definition, which includes [criterion 1], [criterion 2], and [criterion 3].
 
OR
 
'''IF there are no established diagnostic criteria'''
 
There are no established criteria for the diagnosis of [disease name].
 
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
{{WH}}
{{WH}}
{{WS}}
{{WS}}
[[Category:Up-To-Date]]
[[Category:Medicine]]
[[Category:Oncology]]
[[Category:Nephrology]]

Latest revision as of 23:57, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

Overview

The gold standard test for the diagnosis of renal oncoytoma is renal biopsy and histopathological charcarterization.

Diagnostic Study of Choice

The gold standard test for the diagnosis of renal oncoytoma is renal biopsy and histopathological charcarterization. Histologically, renal oncocytomas exhibit nests and tubular structures lined by cells with eosinophilic cytoplasmic granularity, edematous myxoid or hyalinized stroma.[1][2][3]

References

  1. ↑ Wobker SE, Williamson SR (2017). "Modern Pathologic Diagnosis of Renal Oncocytoma". J Kidney Cancer VHL. 4 (4): 1–12. doi:10.15586/jkcvhl.2017.96. PMC 5634396. PMID 29090117.
  2. ↑ Smith CJ, Wang MX, Feely M, Otto B, Grajo JR (May 2017). "Oncocytoma: A Differential Consideration for an Incidentally Detected FDG-Avid Renal Mass on PET/CT". J Radiol Case Rep. 11 (5): 27–33. doi:10.3941/jrcr.v11i5.3117. PMC 5743137. PMID 29299091.
  3. ↑ Neuzillet Y, Lechevallier E, Andre M, Daniel L, Nahon O, Coulange C (December 2005). "Follow-up of renal oncocytoma diagnosed by percutaneous tumor biopsy". Urology. 66 (6): 1181–5. doi:10.1016/j.urology.2005.06.001. PMID 16360437.

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