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== Symptoms ==
==Overview==
The hallmark of restless leg syndrome is urge to move the legs. A positive history of [[iron deficiency anemia]] and [[Kidney diseases]] and a positive family history of restless leg syndrome is suggestive of  restless leg syndrome. The most common symptoms of  restless leg syndrome include Urge to move the legs, [[itching]] sensation, burning sensation, creeping sensation, pulling sensation and [[aching]].


*"An urge to move, usually due to uncomfortable sensations that occur primarily in the legs."  
==History and Symptoms==
The sensations are unusual and unlike other common sensations, and those with RLS have a hard time describing them. People use words such as: uncomfortable, antsy, electrical, creeping, painful, itching, pins and needles, pulling, creepy-crawly, ants inside the legs, and many others. The sensation and the urge can occur in any body part; the most cited location is legs, followed by arms. Some people have little or no sensation, yet still have a strong urge to move.  
*The hallmark of restless leg syndrome is urge to move the legs. A positive history of [[iron deficiency anemia]] and [[Kidney diseases]] and a positive family history of restless leg syndrome is suggestive of restless leg syndrome.
*The most common symptoms of  restless leg syndrome include Urge to move the legs, [[itching]] sensation, burning sensation, creeping sensation, pulling sensation and [[aching]].
===History===
Patients with restless legs syndrome may have a positive history of:
*Family history of restless legs syndrome<ref name="pmid17068272">{{cite journal| author=Dhawan V, Ali M, Chaudhuri KR| title=Genetic aspects of restless legs syndrome. | journal=Postgrad Med J | year= 2006 | volume= 82 | issue= 972 | pages= 626-9 | pmid=17068272 | doi=10.1136/pgmj.2006.045690 | pmc=2653903 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17068272  }} </ref>
* [[Iron deficiency anemia]]<ref name="pmid17566122">{{cite journal| author=Allen RP, Earley CJ| title=The role of iron in restless legs syndrome. | journal=Mov Disord | year= 2007 | volume= 22 Suppl 18 | issue=  | pages= S440-8 | pmid=17566122 | doi=10.1002/mds.21607 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17566122  }} </ref>
* [[Kidney diseases]]<ref name="pmid27765002">{{cite journal| author=Lin Z, Zhao C, Luo Q, Xia X, Yu X, Huang F| title=Prevalence of restless legs syndrome in chronic kidney disease: a systematic review and meta-analysis of observational studies. | journal=Ren Fail | year= 2016 | volume= 38 | issue= 9 | pages= 1335-1346 | pmid=27765002 | doi=10.1080/0886022X.2016.1227564 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27765002  }} </ref>


*"Motor restlessness, expressed as activity, that relieves the urge to move."   
===Common Symptoms===
Common symptoms of [disease] include:<ref name="pmid23748511">{{cite journal| author=Bogan RK, Cheray JA| title=Restless legs syndrome: a review of diagnosis and management in primary care. | journal=Postgrad Med | year= 2013 | volume= 125 | issue= 3 | pages= 99-111 | pmid=23748511 | doi=10.3810/pgm.2013.05.2636 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23748511  }} </ref><ref name="pmid25167326">{{cite journal| author=Karroum EG, Golmard JL, Leu-Semenescu S, Arnulf I| title=Painful restless legs syndrome: a severe, burning form of the disease. | journal=Clin J Pain | year= 2015 | volume= 31 | issue= 5 | pages= 459-66 | pmid=25167326 | doi=10.1097/AJP.0000000000000133 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25167326  }} </ref>
*Urge to move the legs
*Uncomfortable and bothersome sensations in the affected limbs include:
**[[Itching]] sensation
**Burning sensation
**Creeping sensation
**Pulling sensation
**[[Aching]]
Symptoms appear when the legs are at rest and are worst in the evening and at night.<ref name="pmid19412499">{{cite journal| author=Bogan RK| title=Effects of restless legs syndrome (RLS) on sleep. | journal=Neuropsychiatr Dis Treat | year= 2006 | volume= 2 | issue= 4 | pages= 513-9 | pmid=19412499 | doi= | pmc=2671944 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19412499 }} </ref>


Movement will usually bring immediate relief, however, often only temporary and partial. Walking is most common; however, doing stretches, yoga, biking, or other physical activity may relieve the symptoms. Constant and fast up-and-down movement of the leg, coined "sewing machine legs" by at least one RLS sufferer, is often done to keep the sensations at bay without having to walk. Sometimes a specific type of movement will help a person more than another.   
Symptoms force patients to keep moving their legs.<ref name="pmid19817966" />
 
*"Worsening of symptoms by relaxation." 
 
Any type of inactivity involving sitting or lying – reading a book, a plane ride, watching TV or a movie, taking a nap - can trigger the sensations and urge to move. This depends on several factors: the severity of the person’s RLS, the degree of restfulness, the duration of the inactivity, etc.
 
*"Variability over the course of the day-night cycle, with symptoms worse in the evening and early in the night."  
 
While some only experience RLS at bedtime and others experience it throughout the day and night, most sufferers experience the worst symptoms in the evening and the least in the morning.


Symptoms get worse when sitting or lying down.<ref name="pmid19817966">{{cite journal| author=Ekbom K, Ulfberg J| title=Restless legs syndrome. | journal=J Intern Med | year= 2009 | volume= 266 | issue= 5 | pages= 419-31 | pmid=19817966 | doi=10.1111/j.1365-2796.2009.02159.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19817966  }} </ref>
==References==
==References==
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[[Category:Sleep disorders]]
[[Category:Sleep disorders]]
[[Category:Syndromes]]
[[Category:Syndromes]]
[[Category:Neurology]]
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Latest revision as of 23:58, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

The hallmark of restless leg syndrome is urge to move the legs. A positive history of iron deficiency anemia and Kidney diseases and a positive family history of restless leg syndrome is suggestive of restless leg syndrome. The most common symptoms of restless leg syndrome include Urge to move the legs, itching sensation, burning sensation, creeping sensation, pulling sensation and aching.

History and Symptoms

  • The hallmark of restless leg syndrome is urge to move the legs. A positive history of iron deficiency anemia and Kidney diseases and a positive family history of restless leg syndrome is suggestive of restless leg syndrome.
  • The most common symptoms of restless leg syndrome include Urge to move the legs, itching sensation, burning sensation, creeping sensation, pulling sensation and aching.

History

Patients with restless legs syndrome may have a positive history of:

Common Symptoms

Common symptoms of [disease] include:[4][5]

  • Urge to move the legs
  • Uncomfortable and bothersome sensations in the affected limbs include:
    • Itching sensation
    • Burning sensation
    • Creeping sensation
    • Pulling sensation
    • Aching

Symptoms appear when the legs are at rest and are worst in the evening and at night.[6]

Symptoms force patients to keep moving their legs.[7]

Symptoms get worse when sitting or lying down.[7]

References

  1. Dhawan V, Ali M, Chaudhuri KR (2006). "Genetic aspects of restless legs syndrome". Postgrad Med J. 82 (972): 626–9. doi:10.1136/pgmj.2006.045690. PMC 2653903. PMID 17068272.
  2. Allen RP, Earley CJ (2007). "The role of iron in restless legs syndrome". Mov Disord. 22 Suppl 18: S440–8. doi:10.1002/mds.21607. PMID 17566122.
  3. Lin Z, Zhao C, Luo Q, Xia X, Yu X, Huang F (2016). "Prevalence of restless legs syndrome in chronic kidney disease: a systematic review and meta-analysis of observational studies". Ren Fail. 38 (9): 1335–1346. doi:10.1080/0886022X.2016.1227564. PMID 27765002.
  4. Bogan RK, Cheray JA (2013). "Restless legs syndrome: a review of diagnosis and management in primary care". Postgrad Med. 125 (3): 99–111. doi:10.3810/pgm.2013.05.2636. PMID 23748511.
  5. Karroum EG, Golmard JL, Leu-Semenescu S, Arnulf I (2015). "Painful restless legs syndrome: a severe, burning form of the disease". Clin J Pain. 31 (5): 459–66. doi:10.1097/AJP.0000000000000133. PMID 25167326.
  6. Bogan RK (2006). "Effects of restless legs syndrome (RLS) on sleep". Neuropsychiatr Dis Treat. 2 (4): 513–9. PMC 2671944. PMID 19412499.
  7. 7.0 7.1 Ekbom K, Ulfberg J (2009). "Restless legs syndrome". J Intern Med. 266 (5): 419–31. doi:10.1111/j.1365-2796.2009.02159.x. PMID 19817966.

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