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'''For the WikiDoc page for this topic, click [[Sepsis|here]]'''
'''For the WikiDoc page for this topic, click [[Sepsis|here]]'''
{{Sepsis (patient information)}}
{{Sepsis (patient information)}}


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==Overview==
==Overview==
Sepsis is a severe illness in which the bloodstream is overwhelmed by bacteria.
Sepsis is a severe illness in which the bloodstream is overwhelmed by [[bacteria]].


==What are the symptoms of Sepsis?==
==What are the symptoms of Sepsis?==
In sepsis, blood pressure drops, resulting in shock. Major organs and body systems, including the kidneys, liver, lungs, and central nervous system, stop working properly.
In sepsis, [[blood pressure]] drops, resulting in [[shock]]. Major organs and body systems, including the [[kidney]]s, [[liver]], [[lung]]s, and [[central nervous system]], stop working properly.


A change in mental status and hyperventilation may be the earliest signs of sepsis. In general, symptoms of sepsis can include:
A change in mental status and [[hyperventilation]] may be the earliest signs of sepsis. In general, symptoms of sepsis can include:


Chills
*[[Chills]]
Confusion or delirium
*[[Confusion]] or [[delirium]]
Decreased urine output
*Decreased urine output
Fever or low body temperature (hypothermia)
*[[Fever]] or low body temperature ([[hypothermia]])
Hyperventilation
*[[Hyperventilation]]
Lightheadedness due to low blood pressure
*[[Lightheadedness]] due to low blood pressure
Rapid heart beat
*Rapid heart beat
Shaking
*Shaking
Skin rash
*Skin [[rash]]
Warm skin
*Warm skin


==What causes Sepsis?==
==What causes Sepsis?==
Sepsis is caused by a bacterial infection that can begin anywhere in the body. Common places where an infection might start include:
Sepsis is caused by a bacterial [[infection]] that can begin anywhere in the body. Common places where an infection might start include:


The bowel (usually seen with peritonitis)
*The [[bowel]] (usually seen with [[peritonitis]])
The kidneys (upper urinary tract infection or pyelonephritis)
*The [[kidney]]s (upper [[urinary tract infection]] or [[pyelonephritis]])
The lining of the brain (meningitis)
*The lining of the [[brain]] ([[meningitis]])
The liver or the gall bladder
*The [[liver]] or the [[gall bladder]]
The lungs (bacterial pneumonia)
*The [[lungs]] (bacterial [[pneumonia]])
The skin (cellulitis)
*The skin ([[cellulitis]])


In children, sepsis may accompany infection of the bone (osteomyelitis). In hospitalized patients, common sites of infection include intravenous lines, surgical wounds, surgical drains, and sites of skin breakdown known as bedsores (decubitus ulcers).
In children, sepsis may accompany infection of the bone ([[osteomyelitis]]). In hospitalized patients, common sites of infection include intravenous lines, surgical wounds, surgical drains, and sites of skin breakdown known as bedsores ([[decubitus ulcer]]s).


==Who is at highest risk?==
==Who is at highest risk?==
Any infectious site can lead to sepsis if not taken proper care
Any infectious site can lead to sepsis if not taken proper care of.


==When to seek urgent medical care?==
==When to seek urgent medical care?==
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==Diagnosis==
==Diagnosis==
The infection is often confirmed by a blood test. However, a blood test may not reveal infection in people who have been receiving antibiotics.
The [[infection]] is often confirmed by a blood test. However, a blood test may not reveal infection in people who have been receiving [[antibiotic]]s.


Other tests that may be done include:
Other tests that may be done include:


Blood gases
*[[Blood gases]]
Kidney function tests
*Kidney function tests
Platelet count
*[[Platelet count]]
White blood cell count
*[[White blood cell count]]
Blood differential
*Blood differential
Fibrin degradation products
*[[Fibrin degradation products]]
Peripheral smear
*[[Peripheral smear]]


==Treatment options==
==Treatment options==
If you have sepsis, you will be admitted to a hospital, usually the intensive care unit (ICU). Antibiotics are given through a vein (intravenously).Oxygen, fluids given through a vein, and medications that increase blood pressure may be needed. Dialysis may be necessary if there is kidney failure. A breathing machine (mechanical ventilation) is necessary if there is lung failure.For some patients, treatment with powerful anti-inflammatory medications called corticosteroids or recombinant human activated protein C may be helpful.
If you have sepsis, you will be admitted to a hospital, usually the intensive care unit (ICU). [[Antibiotic]]s are given through a vein (intravenously). Oxygen, fluids given through a vein, and medications that increase [[blood pressure]] may be needed. [[Dialysis]] may be necessary if there is kidney failure. A breathing machine (mechanical ventilation) is necessary if there is lung failure. For some patients, treatment with powerful anti-inflammatory medications called [[corticosteroid]]s or recombinant human activated protein C may be helpful.
 
===Medications to avoid===
{{MedCondContrPI
 
|MedCond =Sepsis|Etanercept|Sitagliptin And Metformin Hydrochloride}}


==Where to find medical care for Sepsis?==
==Where to find medical care for Sepsis?==
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==Possible complications==
==Possible complications==
Death
*[[Disseminated intravascular coagulation]]
Disseminated intravascular coagulation
*Problems with blood flow to vital organs ([[brain]], [[heart]], [[kidney]]s)
Problems with blood flow to vital organs (brain, heart, kidneys)
*Septic [[shock]]
Septic shock
*Death
 
==Sources==
==Sources==
http://www.nlm.nih.gov/medlineplus/sepsis.html
http://www.nlm.nih.gov/medlineplus/sepsis.html


[[Category:Cardiology patient information]]
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[[Category:Intensive care medicine]]
[[Category:Causes of death]]
[[Category:Emergency medicine]]
[[Category:Emergency medicine]]
[[Category:Emergency medicine patient information]]
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[[Category:Gastroenterology patient information]]
[[Category:Patient information]]
[[Category:Gastroenterology]]
[[Category:Emergency mdicine]]
[[Category:Gynecology patient information]]
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[[Category:Gynecology]]
[[Category:Infectious disease patient information]]
[[Category:Infectious disease]]
[[Category:Infectious disease]]
[[Category:Obstetrics]]
[[Category:Obstetrics patient information]]
[[Category:Orthopedics]]
[[Category:Otolaryngology]]
[[Category:Orthopedics patient information]]
[[Category:Otolaryngology patient information]]
[[Category:Pediatrics patient information]]
[[Category:Pulmonology]]
[[Category:Pulmonary patient information]]
[[Category:Pediatrics]]
[[Category:Patient information]]
[[Category:Overview complete]]
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Latest revision as of 00:07, 30 July 2020

For the WikiDoc page for this topic, click here

Sepsis

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

When to seek urgent medical care?

Diagnosis

Treatment options

Where to find medical care for Sepsis?

What to expect (Outlook/Prognosis)?

Possible complications

Sepsis On the Web

Ongoing Trials at Clinical Trials.gov

Images of Sepsis

Videos on Sepsis

FDA on Sepsis

CDC on Sepsis

Sepsis in the news

Blogs on Sepsis

Directions to Hospitals Treating Sepsis

Risk calculators and risk factors for Sepsis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Sepsis is a severe illness in which the bloodstream is overwhelmed by bacteria.

What are the symptoms of Sepsis?

In sepsis, blood pressure drops, resulting in shock. Major organs and body systems, including the kidneys, liver, lungs, and central nervous system, stop working properly.

A change in mental status and hyperventilation may be the earliest signs of sepsis. In general, symptoms of sepsis can include:

What causes Sepsis?

Sepsis is caused by a bacterial infection that can begin anywhere in the body. Common places where an infection might start include:

In children, sepsis may accompany infection of the bone (osteomyelitis). In hospitalized patients, common sites of infection include intravenous lines, surgical wounds, surgical drains, and sites of skin breakdown known as bedsores (decubitus ulcers).

Who is at highest risk?

Any infectious site can lead to sepsis if not taken proper care of.

When to seek urgent medical care?

Call a doctor if you develop symptoms of sepsis

Diagnosis

The infection is often confirmed by a blood test. However, a blood test may not reveal infection in people who have been receiving antibiotics.

Other tests that may be done include:

Treatment options

If you have sepsis, you will be admitted to a hospital, usually the intensive care unit (ICU). Antibiotics are given through a vein (intravenously). Oxygen, fluids given through a vein, and medications that increase blood pressure may be needed. Dialysis may be necessary if there is kidney failure. A breathing machine (mechanical ventilation) is necessary if there is lung failure. For some patients, treatment with powerful anti-inflammatory medications called corticosteroids or recombinant human activated protein C may be helpful.

Medications to avoid

Patients diagnosed with Sepsis should avoid using the following medications:


Where to find medical care for Sepsis?

Directions to Hospitals Treating Sepsis

What to expect (Outlook/Prognosis)?

Sepsis is often life threatening, especially in people with a weakened immune system or with a chronic illness.

Possible complications

Sources

http://www.nlm.nih.gov/medlineplus/sepsis.html

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