Sepsis history and symptoms: Difference between revisions

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==Overview==
==Overview==
Symptoms of sepsis are often related to the underlying infectious process. When the infection crosses into the bloodstream the resulting symptoms of sepsis occur fever, chills, and rigors, confusion, anxiety, difficulty breathing, fatigue and malaise, nausea and vomiting.
Symptoms of sepsis are often related to the underlying infectious process. When the infection crosses into the bloodstream the resulting symptoms of sepsis occur fever, chills, and rigors, confusion, anxiety, difficulty breathing, fatigue and malaise, nausea and vomiting.<ref name="pmid17962288">{{cite journal |vauthors=Lever A, Mackenzie I |title=Sepsis: definition, epidemiology, and diagnosis |journal=BMJ |volume=335 |issue=7625 |pages=879–83 |year=2007 |pmid=17962288 |pmc=2043413 |doi=10.1136/bmj.39346.495880.AE |url=}}</ref><ref name="Juneja2012">{{cite journal|last1=Juneja|first1=Deven|title=Severe sepsis and septic shock in the elderly: An overview|journal=World Journal of Critical Care Medicine|volume=1|issue=1|year=2012|pages=23|issn=2220-3141|doi=10.5492/wjccm.v1.i1.23}}</ref><ref name="pmid23983879">{{cite journal |vauthors=Karnatovskaia LV, Festic E |title=Sepsis: a review for the neurohospitalist |journal=Neurohospitalist |volume=2 |issue=4 |pages=144–53 |year=2012 |pmid=23983879 |pmc=3726110 |doi=10.1177/1941874412453338 |url=}}</ref>


==History and Symptoms==
==History and Symptoms==
[[Symptoms]] of sepsis are often related to the underlying [[infectious]] process. When the [[infection]] crosses into the [[bloodstream]] the resulting symptoms of sepsis occur:
[[Symptoms]] of sepsis are often related to the underlying [[infectious]] process. When the [[infection]] crosses into the [[bloodstream]] the resulting symptoms of sepsis occur:<ref name="pmid17962288">{{cite journal |vauthors=Lever A, Mackenzie I |title=Sepsis: definition, epidemiology, and diagnosis |journal=BMJ |volume=335 |issue=7625 |pages=879–83 |year=2007 |pmid=17962288 |pmc=2043413 |doi=10.1136/bmj.39346.495880.AE |url=}}</ref><ref name="Juneja2012">{{cite journal|last1=Juneja|first1=Deven|title=Severe sepsis and septic shock in the elderly: An overview|journal=World Journal of Critical Care Medicine|volume=1|issue=1|year=2012|pages=23|issn=2220-3141|doi=10.5492/wjccm.v1.i1.23}}</ref><ref name="pmid23983879">{{cite journal |vauthors=Karnatovskaia LV, Festic E |title=Sepsis: a review for the neurohospitalist |journal=Neurohospitalist |volume=2 |issue=4 |pages=144–53 |year=2012 |pmid=23983879 |pmc=3726110 |doi=10.1177/1941874412453338 |url=}}</ref>
 
*[[Fever]]
*[[Fever]]
*A [[capillary leak syndrome]] can develop with severe [[swelling]], [[edema]], and third spacing of fluids.
*A [[capillary leak syndrome]] can develop with severe [[swelling]], [[edema]], and third spacing of fluids.
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Symptoms due to the focal involvement of organs by the bacteria can give clues to the etiology of sepsis. Such symptoms include the following:
Symptoms due to the focal involvement of organs by the bacteria can give clues to the etiology of sepsis. Such symptoms include the following:
{| class="wikitable"
{| class="wikitable"
!Organ system involvement
!Organ system
!Symtpoms
!Symptoms
!
!
|-
|-
|Head and Neck  
|Head and Neck  
|
|
* Headache
* [[Headache]]
* Neck stiffness
* [[Neck stiffness]]
* altered mental status
* [[Altered mental status]]
* Earache
* [[Otalgia|Earache]]
* Sore throat
* [[Sore throat]]
* Sinus pain or tenderness
* Sinus pain or tenderness
* Cervical or submandibular lymphadenopathy
* Cervical or submandibular lymphadenopathy
|
|
|-
|-
|Pulmonary  
|Pulmonary  
|
|
* Productive Cough
* Productive [[cough]]
* Pleuritic chest pain
* [[Pleuritic chest pain]]
* Dyspnea
* [[Dyspnea]]
* Dullness on percussion  
* Dullness on percussion  
* Bronchial breath sounds with localized rales, or any evidence of consolidation
* Bronchial breath sounds with localized rales or any evidence of consolidation
|
|
|-
|-
|Cardiac
|Cardiac
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* Onset of new murmur  
* Onset of new murmur  
* H/O of IV drug use
* H/O of IV drug use
|
|
|-
|-
|Abdominal and gastrointestinal  
|Abdominal and gastrointestinal  
|
|
* Diarrhea
* [[Diarrhea]]
* Abdominal pain and distention
* Abdominal pain and distention
* Guarding or rebound tenderness
* Guarding or rebound tenderness
* Rectal tenderness or swelling
* Rectal tenderness or swelling
|
|
|-
|-
|Pelvic and genitourinary
|Pelvic and genitourinary
|
|
* Flank pain
* [[Flank pain]]
* Adnexal tenderness or masses
* Adnexal tenderness or masses
* Vaginal or urethral discharge
* [[Vaginal discharge|Vaginal]] or [[urethral discharge]]
* Dysuria, frequency, and urgency
* [[Dysuria]], frequency, and [[Urinary urgency|urgency]]
|
|
|-
|-
|Musculoskeletal
|Musculoskeletal
|
|
* Localized limb pain or tenderness
* Localized limb pain or tenderness
* Focal erythema, edema
* Focal [[erythema]], edema
* Swollen joint crepitus in necrotizing infections
* Swollen joint crepitus in necrotizing infections
* Joint effusions
* Joint effusions
|
|
|-
|-
|Skin
|Skin
|
|
* Petechiae
* [[Petechiae]]
* Purpura
* [[Purpura]]
* Erythema, ulceration, bullous formation, and fluctuance
* [[Erythema]], [[ulceration]], bullous formation, and fluctuance
|
|
|}
|}


==References==
==References==
{{reflist|2}}
{{reflist|2}}
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Latest revision as of 00:08, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]

Synonyms and keywords: sepsis syndrome; septic shock; septicemia

Overview

Symptoms of sepsis are often related to the underlying infectious process. When the infection crosses into the bloodstream the resulting symptoms of sepsis occur fever, chills, and rigors, confusion, anxiety, difficulty breathing, fatigue and malaise, nausea and vomiting.[1][2][3]

History and Symptoms

Symptoms of sepsis are often related to the underlying infectious process. When the infection crosses into the bloodstream the resulting symptoms of sepsis occur:[1][2][3]

Symptoms due to the focal involvement of organs by the bacteria can give clues to the etiology of sepsis. Such symptoms include the following:

Organ system Symptoms
Head and Neck
Pulmonary
Cardiac
  • Onset of new murmur
  • H/O of IV drug use
Abdominal and gastrointestinal
  • Diarrhea
  • Abdominal pain and distention
  • Guarding or rebound tenderness
  • Rectal tenderness or swelling
Pelvic and genitourinary
Musculoskeletal
  • Localized limb pain or tenderness
  • Focal erythema, edema
  • Swollen joint crepitus in necrotizing infections
  • Joint effusions
Skin

References

  1. 1.0 1.1 Lever A, Mackenzie I (2007). "Sepsis: definition, epidemiology, and diagnosis". BMJ. 335 (7625): 879–83. doi:10.1136/bmj.39346.495880.AE. PMC 2043413. PMID 17962288.
  2. 2.0 2.1 Juneja, Deven (2012). "Severe sepsis and septic shock in the elderly: An overview". World Journal of Critical Care Medicine. 1 (1): 23. doi:10.5492/wjccm.v1.i1.23. ISSN 2220-3141.
  3. 3.0 3.1 Karnatovskaia LV, Festic E (2012). "Sepsis: a review for the neurohospitalist". Neurohospitalist. 2 (4): 144–53. doi:10.1177/1941874412453338. PMC 3726110. PMID 23983879.

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