Sheehan's syndrome diagnostic criteria: Difference between revisions
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{{Sheehan's syndrome}} | {{Sheehan's syndrome}} | ||
{{CMG}}; {{IQ}} | {{CMG}}; {{AE}}{{IQ}} | ||
==Overview== | ==Overview== | ||
Diagnosis of Sheehan's syndrome is made on clinical basis with a recent/remote history of traumatic delivery or delivery complicated by [[hypotension]]. | |||
==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
*Diagnosis is made on clinical basis with a recent/remote history of traumatic delivery or delivery complicated by hypotension. | *There is no specific established diagnostic criteria for Sheehan's syndrome. | ||
*[[Diagnosis]] of Sheehan's syndrome is made on clinical basis with a recent/remote history of traumatic delivery or delivery complicated by [[hypotension]]. | |||
*[[Diagnosis]] is mostly clinical but following steps are required to make the [[diagnosis]] of Sheehan's syndrome: | |||
**Detailed medical history | |||
**Measurement of [[pituitary hormone]] levels in blood | |||
**Pituitary [[hormone]] stimulation tests:<ref name="pmid6316866">{{cite journal |vauthors=Cunningham SK, Moore A, McKenna TJ |title=Normal cortisol response to corticotropin in patients with secondary adrenal failure |journal=Arch. Intern. Med. |volume=143 |issue=12 |pages=2276–9 |year=1983 |pmid=6316866 |doi= |url=}}</ref><ref name="pmid7962298">{{cite journal |vauthors=Grinspoon SK, Biller BM |title=Clinical review 62: Laboratory assessment of adrenal insufficiency |journal=J. Clin. Endocrinol. Metab. |volume=79 |issue=4 |pages=923–31 |year=1994 |pmid=7962298 |doi=10.1210/jcem.79.4.7962298 |url=}}</ref> | |||
***[[Insulin tolerance test|Insulin tolerance]] | |||
***[[chlorpromazine]] | |||
***[[metoclopramide]] | |||
***[[clomiphene citrate|Comiphene citrate]] stimulation tests | |||
**Imaging ([[Magnetic resonance imaging|MRI]] preferred on [[CT]]) | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Medicine]] | |||
[[Category:Endocrinology]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Emergency medicine]] | |||
[[Category:Obstetrics]] | |||
Latest revision as of 00:09, 30 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Iqra Qamar M.D.[2]
Overview
Diagnosis of Sheehan's syndrome is made on clinical basis with a recent/remote history of traumatic delivery or delivery complicated by hypotension.
Diagnostic Criteria
- There is no specific established diagnostic criteria for Sheehan's syndrome.
- Diagnosis of Sheehan's syndrome is made on clinical basis with a recent/remote history of traumatic delivery or delivery complicated by hypotension.
- Diagnosis is mostly clinical but following steps are required to make the diagnosis of Sheehan's syndrome:
- Detailed medical history
- Measurement of pituitary hormone levels in blood
- Pituitary hormone stimulation tests:[1][2]
- Insulin tolerance
- chlorpromazine
- metoclopramide
- Comiphene citrate stimulation tests
- Imaging (MRI preferred on CT)
References
- ↑ Cunningham SK, Moore A, McKenna TJ (1983). "Normal cortisol response to corticotropin in patients with secondary adrenal failure". Arch. Intern. Med. 143 (12): 2276–9. PMID 6316866.
- ↑ Grinspoon SK, Biller BM (1994). "Clinical review 62: Laboratory assessment of adrenal insufficiency". J. Clin. Endocrinol. Metab. 79 (4): 923–31. doi:10.1210/jcem.79.4.7962298. PMID 7962298.