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__NOTOC__
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{{Sjögren's syndrome}}
{{Sjögren's syndrome}}
{{CMG}} {{AE}} {{F.K}}
==Overview==
Physical examination of patients with is usually remarkable for dryness of all [[mucous membranes]] such as [[mouth]], [[Eye|eyes]], lips, [[anal]] and [[rectal]].
==Physical Examination==
*Physical examination of patients with is usually remarkable for dryness of all [[mucous membranes]] such as [[mouth]], [[Eye|eyes]], lips, [[anal]] and [[rectal]].<ref name="pmid16453296">{{cite journal |vauthors=Lopate G, Pestronk A, Al-Lozi M, Lynch T, Florence J, Miller T, Levine T, Rampy T, Beson B, Ramneantu I |title=Peripheral neuropathy in an outpatient cohort of patients with Sjögren's syndrome |journal=Muscle Nerve |volume=33 |issue=5 |pages=672–6 |date=May 2006 |pmid=16453296 |doi=10.1002/mus.20514 |url=}}</ref><ref name="pmid19254127">{{cite journal |vauthors=Antoniazzi RP, Miranda LA, Zanatta FB, Islabão AG, Gustafsson A, Chiapinotto GA, Oppermann RV |title=Periodontal conditions of individuals with Sjögren's syndrome |journal=J. Periodontol. |volume=80 |issue=3 |pages=429–35 |date=March 2009 |pmid=19254127 |doi=10.1902/jop.2009.080350 |url=}}</ref><ref name="pmid19307256">{{cite journal |vauthors=Riccieri V, Sciarra I, Ceccarelli F, Alessandri C, Croia C, Vasile M, Modesti MG, Priori R, Valesini G |title=Nailfold capillaroscopy abnormalities are associated with the presence of anti-endothelial cell antibodies in Sjogren's syndrome |journal=Rheumatology (Oxford) |volume=48 |issue=6 |pages=704–6 |date=June 2009 |pmid=19307256 |doi=10.1093/rheumatology/kep051 |url=}}</ref><ref name="pmid18085734">{{cite journal |vauthors=Ren H, Wang WM, Chen XN, Zhang W, Pan XX, Wang XL, Lin Y, Zhang S, Chen N |title=Renal involvement and followup of 130 patients with primary Sjögren's syndrome |journal=J. Rheumatol. |volume=35 |issue=2 |pages=278–84 |date=February 2008 |pmid=18085734 |doi= |url=}}</ref><ref name="pmid16397619">{{cite journal |vauthors=Versura P, Frigato M, Cellini M, Mulè R, Malavolta N, Campos EC |title=Diagnostic performance of tear function tests in Sjogren's syndrome patients |journal=Eye (Lond) |volume=21 |issue=2 |pages=229–37 |date=February 2007 |pmid=16397619 |doi=10.1038/sj.eye.6702204 |url=}}</ref><ref name="pmid18599017">{{cite journal |vauthors=Lemp MA |title=Advances in understanding and managing dry eye disease |journal=Am. J. Ophthalmol. |volume=146 |issue=3 |pages=350–356 |date=September 2008 |pmid=18599017 |doi=10.1016/j.ajo.2008.05.016 |url=}}</ref>
===Appearance of the Patient===
*Patients with Sjögren's syndrome usually appear good.
===Vital Signs===
*Vital sign might be normal.
===Skin===
*Dryness
*[[Scaling skin|Scaling]]
*Partial or complete loss of [[sweating]]
*Dry, sparse, and brittle hair
*Diffuse [[alopecia]] may involve the [[scalp]], [[Limb (anatomy)|limbs]], [[axilla]], or [[pubis]]
*Nail folds may show capillaroscopic abnormalities
*Nonpalpable or palpable, vasculitic [[purpura]], 2-3 mm lesions on the [[Human leg|lower extremities]]
*Annular [[erythema]] with scales on the face and neck
===HEENT===
*[[Mucus|Mucous]] dryness
*Red, smooth, and dry [[tongue]]
*Hyperlobulated [[tongue]] with loss of filiform [[Papilla|papillae]]
*Absence of salivary pooling under the [[tongue]]
*[[Dental caries]]
*[[Gingiva|Gingival]] inflammation
*Red, dry, and scaly lips
*Cracks at the corners of the mouth
*Chronic [[oral]] [[candidiasis]]
===Neck===
*Bilateral [[parotid gland enlargement]]
===Lungs===
*Bibasilar [[rales]]
*[[Wheezing]] may be present
===Heart===
* Cardiovascular examination of patients with Sjögren's syndrome is usually normal.
===Abdomen===
*[[Splenomegaly]]
===Back===
* Back examination of patients with Sjögren's syndrome is usually normal.
===Genitourinary===
*Irritated [[bladder]]
*Suprapubic [[tenderness]]
*Atrophic changes in the [[vulva]] and [[Vagina|vagin]]
*Dryness of the [[anal]] and [[rectal]] [[mucous membranes]]
===Neuromuscular===
*Patient is usually oriented to persons, place, and time.
*Glasgow coma scale is 15/15
*[[Paraparesis]] maybe present
*[[Paraplegia]] may be present
===Extremities===
*Symmetrical, polyarticular, [[inflammatory arthritis]]


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==References==
==References==
{{reflist|2}}
{{reflist|2}}
{{WH}}
 
{{WS}}
[[Category:Medicine]]
[[Category:Needs content]]
[[Category:Immunology]]
[[Category:Autoimmune diseases]]
[[Category:Rheumatology]]
[[Category:Rheumatology]]
[[Category:Syndromes]]
[[Category:Up-To-Date]]

Latest revision as of 00:12, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]

Overview

Physical examination of patients with is usually remarkable for dryness of all mucous membranes such as mouth, eyes, lips, anal and rectal.

Physical Examination

Appearance of the Patient

  • Patients with Sjögren's syndrome usually appear good.

Vital Signs

  • Vital sign might be normal.

Skin

HEENT

Neck

Lungs

Heart

  • Cardiovascular examination of patients with Sjögren's syndrome is usually normal.

Abdomen

Back

  • Back examination of patients with Sjögren's syndrome is usually normal.

Genitourinary

Neuromuscular

  • Patient is usually oriented to persons, place, and time.
  • Glasgow coma scale is 15/15
  • Paraparesis maybe present
  • Paraplegia may be present

Extremities

References

  1. Lopate G, Pestronk A, Al-Lozi M, Lynch T, Florence J, Miller T, Levine T, Rampy T, Beson B, Ramneantu I (May 2006). "Peripheral neuropathy in an outpatient cohort of patients with Sjögren's syndrome". Muscle Nerve. 33 (5): 672–6. doi:10.1002/mus.20514. PMID 16453296.
  2. Antoniazzi RP, Miranda LA, Zanatta FB, Islabão AG, Gustafsson A, Chiapinotto GA, Oppermann RV (March 2009). "Periodontal conditions of individuals with Sjögren's syndrome". J. Periodontol. 80 (3): 429–35. doi:10.1902/jop.2009.080350. PMID 19254127.
  3. Riccieri V, Sciarra I, Ceccarelli F, Alessandri C, Croia C, Vasile M, Modesti MG, Priori R, Valesini G (June 2009). "Nailfold capillaroscopy abnormalities are associated with the presence of anti-endothelial cell antibodies in Sjogren's syndrome". Rheumatology (Oxford). 48 (6): 704–6. doi:10.1093/rheumatology/kep051. PMID 19307256.
  4. Ren H, Wang WM, Chen XN, Zhang W, Pan XX, Wang XL, Lin Y, Zhang S, Chen N (February 2008). "Renal involvement and followup of 130 patients with primary Sjögren's syndrome". J. Rheumatol. 35 (2): 278–84. PMID 18085734.
  5. Versura P, Frigato M, Cellini M, Mulè R, Malavolta N, Campos EC (February 2007). "Diagnostic performance of tear function tests in Sjogren's syndrome patients". Eye (Lond). 21 (2): 229–37. doi:10.1038/sj.eye.6702204. PMID 16397619.
  6. Lemp MA (September 2008). "Advances in understanding and managing dry eye disease". Am. J. Ophthalmol. 146 (3): 350–356. doi:10.1016/j.ajo.2008.05.016. PMID 18599017.