Waldenström's macroglobulinemia classification: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Waldenström's macroglobulinemia}} | {{Waldenström's macroglobulinemia}} | ||
{{CMG}}; {{AE}} {{S.M.}}, {{RAK}}; {{GRR}} {{Nat}} | |||
==Overview== | |||
There is no established [[system]] for the [[classification]] of [[Waldenström's macroglobulinemia|Waldenstrom's macroglobulinemia]]. However, according to a devised [[criteria]] [[Based on Symptoms|based upon patient's symptoms]], [[Waldenström's macroglobulinemia]] can be further [[Classification|classified]] into smoldering/[[asymptomatic]] and [[symptomatic]] [[Waldenström's macroglobulinemia|WM]]. | |||
==Classification== | |||
There is no established [[system]] for the [[classification]] of [[Waldenström's macroglobulinemia|Waldenstrom's macroglobulinemia]]. However, according to a devised [[criteria]] [[Based on Symptoms|based upon patient's symptoms]], [[Waldenström's macroglobulinemia]] can be further [[Classification|classified]] into:<ref name="pmid15735132">{{cite journal| author=Dimopoulos MA, Kyle RA, Anagnostopoulos A, Treon SP| title=Diagnosis and management of Waldenstrom's macroglobulinemia. | journal=J Clin Oncol | year= 2005 | volume= 23 | issue= 7 | pages= 1564-77 | pmid=15735132 | doi=10.1200/JCO.2005.03.144 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15735132 }} </ref> | |||
*[[Symptomatic]] [[Waldenstrom macroglobulinemia]] | |||
*[[Asymptomatic]]/Smoldering [[Waldenstrom macroglobulinemia]] (SWM)<ref name="pmid12720119">{{cite journal| author=Kyle RA, Treon SP, Alexanian R, Barlogie B, Björkholm M, Dhodapkar M et al.| title=Prognostic markers and criteria to initiate therapy in Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia. | journal=Semin Oncol | year= 2003 | volume= 30 | issue= 2 | pages= 116-20 | pmid=12720119 | doi=10.1053/sonc.2003.50038 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12720119 }} </ref> | |||
{| | |||
|+ '''Classification of Waldenstrom macroglobulinemia (WM) and Related Disorders''' | |||
! style="background:#4479BA; color: #FFFFFF;" align="center" + |Criteria | |||
! style="background:#4479BA; color: #FFFFFF;" align="center" + |Symptomatic WM | |||
! style="background:#4479BA; color: #FFFFFF;" align="center" + |Asymptomatic WM | |||
! style="background:#4479BA; color: #FFFFFF;" align="center" + |IgM-Related Disorders | |||
! style="background:#4479BA; color: #FFFFFF;" align="center" + |MGUS | |||
|- | |||
! align="center" style="background:#DCDCDC;" + |IgM monoclonal protein | |||
| style="background:#F5F5F5;" align="center" + | + | |||
| style="background:#F5F5F5;" align="center" + | + | |||
| style="background:#F5F5F5;" align="center" + | + | |||
| style="background:#F5F5F5;" align="center" + | + | |||
|- | |||
! align="center" style="background:#DCDCDC;" + |Bone marrow infiltration | |||
| style="background:#F5F5F5;" align="center" + | + | |||
| style="background:#F5F5F5;" align="center" + | + | |||
| style="background:#F5F5F5;" align="center" + | - | |||
| style="background:#F5F5F5;" align="center" + | - | |||
|- | |||
! align="center" style="background:#DCDCDC;" + |Symptoms attributable to IgM | |||
| style="background:#F5F5F5;" align="center" + | + | |||
| style="background:#F5F5F5;" align="center" + | - | |||
| style="background:#F5F5F5;" align="center" + | + | |||
| style="background:#F5F5F5;" align="center" + | - | |||
|- | |||
! align="center" style="background:#DCDCDC;" + |Symptoms attributable to tumor infiltration | |||
| style="background:#F5F5F5;" align="center" + | + | |||
| style="background:#F5F5F5;" align="center" + | - | |||
| style="background:#F5F5F5;" align="center" + | - | |||
| style="background:#F5F5F5;" align="center" + | - | |||
|} | |||
==References== | ==References== | ||
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{{WS}} | {{WS}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Blood]] | [[Category:Blood]] | ||
[[Category:Hematology]] | [[Category:Hematology]] |
Latest revision as of 19:23, 30 July 2020
Waldenström's macroglobulinemia Microchapters |
Differentiating Waldenström's macroglobulinemia from other Diseases |
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Diagnosis |
Treatment |
Case Studies |
Waldenström's macroglobulinemia classification On the Web |
American Roentgen Ray Society Images of Waldenström's macroglobulinemia classification |
Directions to Hospitals Treating Waldenström's macroglobulinemia |
Risk calculators and risk factors for Waldenström's macroglobulinemia classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2], Roukoz A. Karam, M.D.[3]; Grammar Reviewer: Natalie Harpenau, B.S.[4]
Overview
There is no established system for the classification of Waldenstrom's macroglobulinemia. However, according to a devised criteria based upon patient's symptoms, Waldenström's macroglobulinemia can be further classified into smoldering/asymptomatic and symptomatic WM.
Classification
There is no established system for the classification of Waldenstrom's macroglobulinemia. However, according to a devised criteria based upon patient's symptoms, Waldenström's macroglobulinemia can be further classified into:[1]
- Symptomatic Waldenstrom macroglobulinemia
- Asymptomatic/Smoldering Waldenstrom macroglobulinemia (SWM)[2]
Criteria | Symptomatic WM | Asymptomatic WM | IgM-Related Disorders | MGUS |
---|---|---|---|---|
IgM monoclonal protein | + | + | + | + |
Bone marrow infiltration | + | + | - | - |
Symptoms attributable to IgM | + | - | + | - |
Symptoms attributable to tumor infiltration | + | - | - | - |
References
- ↑ Dimopoulos MA, Kyle RA, Anagnostopoulos A, Treon SP (2005). "Diagnosis and management of Waldenstrom's macroglobulinemia". J Clin Oncol. 23 (7): 1564–77. doi:10.1200/JCO.2005.03.144. PMID 15735132.
- ↑ Kyle RA, Treon SP, Alexanian R, Barlogie B, Björkholm M, Dhodapkar M; et al. (2003). "Prognostic markers and criteria to initiate therapy in Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia". Semin Oncol. 30 (2): 116–20. doi:10.1053/sonc.2003.50038. PMID 12720119.