COVID-19-associated diabetes mellitus differential diagnosis: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{CMG}}; {{AE}} | [[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/COVID-19-associated_diabetes_mellitus]] | ||
{{CMG}}; {{AE}} {{TAM}} | |||
==Overview== | ==Overview== | ||
COVID-19-associated diabetes mellitus | COVID-19-associated diabetes mellitus diagnosis should be differentiated from other diseases manifesting with [[polyuria]], [[polydipsia]], and [[hyperglycemia]]. | ||
==Differentiating COVID-19-associated diabetes mellitus from other Diseases== | ==Differentiating COVID-19-associated diabetes mellitus from other Diseases== | ||
*COVID-19-associated diabetes mellitus | *COVID-19-associated diabetes mellitus diagnosis should be differentiated from other diseases manifesting with [[polyuria]], [[polydipsia]], and [[hyperglycemia]]. | ||
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! rowspan="2" style="background: #4479BA; text-align: center;" |{{fontcolor|#FFF|Disease}} | ! rowspan="2" style="background: #4479BA; text-align: center;" |{{fontcolor|#FFF|Disease}} | ||
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| style="padding: 5px 5px; background: #DCDCDC;" align="center" |Transient [[hyperglycemia]]<ref name=" | | style="padding: 5px 5px; background: #DCDCDC;" align="center" |Transient [[hyperglycemia]]<ref name="pmid27027662">{{cite journal| author=Harp JB, Yancopoulos GD, Gromada J| title=Glucagon orchestrates stress-induced hyperglycaemia. | journal=Diabetes Obes Metab | year= 2016 | volume= 18 | issue= 7 | pages= 648-53 | pmid=27027662 | doi=10.1111/dom.12668 | pmc=5084782 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27027662 }} </ref> | ||
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| style="padding: 5px 5px; background: #F5F5F5;" align="center" |New onset diabetes in a patient infected with [[SARS-CoV-2|severe acute respiratory syndrome coronavirus 2]] (SARS-CoV-2) | | style="padding: 5px 5px; background: #F5F5F5;" align="center" |New onset diabetes in a patient infected with [[SARS-CoV-2|severe acute respiratory syndrome coronavirus 2]] (SARS-CoV-2)<ref name="pmid32530585">{{cite journal| author=Rubino F, Amiel SA, Zimmet P, Alberti G, Bornstein S, Eckel RH | display-authors=etal| title=New-Onset Diabetes in Covid-19. | journal=N Engl J Med | year= 2020 | volume= | issue= | pages= | pmid=32530585 | doi=10.1056/NEJMc2018688 | pmc=7304415 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32530585 }} </ref> | ||
|} | |} | ||
*To browse the differential diagnosis of COVID-19, [[COVID-19 differential diagnosis|Click here]]. | *To browse the differential diagnosis of COVID-19, [[COVID-19 differential diagnosis|Click here]]. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Latest revision as of 06:41, 31 July 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tayyaba Ali, M.D.[2]
Overview
COVID-19-associated diabetes mellitus diagnosis should be differentiated from other diseases manifesting with polyuria, polydipsia, and hyperglycemia.
Differentiating COVID-19-associated diabetes mellitus from other Diseases
- COVID-19-associated diabetes mellitus diagnosis should be differentiated from other diseases manifesting with polyuria, polydipsia, and hyperglycemia.
Disease | History and symptoms | Laboratory findings | Additional findings | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyuria | Polydipsia | Polyphagia | Weight loss | Weight gain | Serum glucose | Urinary Glucose | Urine PH | Serum Sodium | Urinary Glucose | 24 hrs cortisol level | C-peptide level | Serum glucagon | ||
Type 1 Diabetes mellitus[1] | + | + | + | + | - | ↑ | ↑ | Normal | Normal | N/↑ | Normal | ↓ | Normal | Auto antibodies present
(Anti GAD-65 and anti insulin anti bodies) |
Type 2 Diabetes mellitus[1] | + | + | + | + | - | ↑ | ↑ | Normal | Normal | ↑ | Normal | Normal | ↑ | Acanthosis nigricans |
Maturity onset diabetes of young[2] | + | + | + | - | + | ↑ | ↑ | Normal | Normal | ↑ | Normal | Normal | N | - |
Psychogenic polydipsia[3] | + | + | - | - | - | Normal | Normal | Normal | ↓ | Normal | Normal | Normal | Normal | - |
Diabetes insipidus[3] | + | + | - | - | - | Normal | Normal | Normal | ↑ | Normal | Normal | Normal | Normal | - |
Transient hyperglycemia[4] | - | - | - | - | - | ↑ | ↑ | Normal | Normal | ↑ | Normal | Normal | N/↑ | In hospitalized patients especially in ICU and CCU |
Steroid therapy[5] | + | - | - | - | + | ↑ | ↑ | Normal | Normal | ↑ | ↑ | N/↑ | N/↑ | Acanthosis nigricans, |
RTA 1[6] | - | - | - | + | - | Normal | Normal | ↑ | Normal | ↑ | Normal | Normal | Normal | Hypokalemia, nephrolithiasis |
Glucagonoma[7] | - | - | - | - | - | ↑ | Normal | Normal | Normal | - | Normal | Normal | ↑ | Necrolytic migratory erythema |
Cushing syndrome[8] | - | - | - | - | + | ↑ | - | Normal | ↓ | N/↑ | ↑ | Normal | Normal | Moon face, obesity, buffalo hump, easy bruisibility |
COVID-19-associated diabetes mellitus[9] | + | + | - | - | - | ↑ | - | - | ↓ | - | - | - | - | New onset diabetes in a patient infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[10] |
- To browse the differential diagnosis of COVID-19, Click here.
References
- ↑ 1.0 1.1 "Diabetes Overview - Symptoms, Causes, Treatment".
- ↑ "Monogenic Diabetes (Neonatal Diabetes Mellitus & MODY) | NIDDK".
- ↑ 3.0 3.1 "Thirst - excessive: MedlinePlus Medical Encyclopedia".
- ↑ Harp JB, Yancopoulos GD, Gromada J (2016). "Glucagon orchestrates stress-induced hyperglycaemia". Diabetes Obes Metab. 18 (7): 648–53. doi:10.1111/dom.12668. PMC 5084782. PMID 27027662.
- ↑ Tamez-Pérez HE, Quintanilla-Flores DL, Rodríguez-Gutiérrez R, González-González JG, Tamez-Peña AL (2015). "Steroid hyperglycemia: Prevalence, early detection and therapeutic recommendations: A narrative review". World J Diabetes. 6 (8): 1073–81. doi:10.4239/wjd.v6.i8.1073. PMC 4515447. PMID 26240704.
- ↑ "Distal renal tubular acidosis: MedlinePlus Medical Encyclopedia".
- ↑ "Glucagonoma: MedlinePlus Medical Encyclopedia".
- ↑ "Cushing Syndrome | Hypercortisolism | MedlinePlus".
- ↑ Chee YJ, Ng SJH, Yeoh E (2020). "Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus". Diabetes Res Clin Pract. 164: 108166. doi:10.1016/j.diabres.2020.108166. PMC 7194589 Check
|pmc=
value (help). PMID 32339533 Check|pmid=
value (help). - ↑ Rubino F, Amiel SA, Zimmet P, Alberti G, Bornstein S, Eckel RH; et al. (2020). "New-Onset Diabetes in Covid-19". N Engl J Med. doi:10.1056/NEJMc2018688. PMC 7304415 Check
|pmc=
value (help). PMID 32530585 Check|pmid=
value (help).