Dementia laboratory findings: Difference between revisions

	Dementia Microchapters
Patient Information
Overview
Classification
Causes Alzheimer's Disease; Parkinson's Disease; Binswanger's Disease; Dementia with Lewy bodies; Thiamine deficiency; Vascular dementia; Marijuana abuse; AIDS; Neurosyphilis; Normal pressure hydrocephalus; Vitamin B12 deficiency; Vitamin B6 deficiency;
Differential Diagnosis

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Latest revision as of 15:25, 9 October 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Limited laboratory testing is recommended in most patients being evaluated for cognitive impairment and dementia. We do not order other laboratory tests unless there is a specific suspicion for abnormality. Other than the routine lab work for dementia, other laboratory tests are not recommended unless there is a specific suspicion for abnormality.^[1]^[2]

Laboratory Findings

Routine lab work for dementias include:

Complete blood count (CBC)
Toxicology screening
Liver function tests (LFTs)
Calcium
Blood urea nitrogen (BUN) / creatinine
Glucose
Thyroid function tests
Vitamin B12 levels^[3]
Folate levels
Infectious/inflammatory screenings
HIV testing for suspected patients
Rapid plasma reagin (RPR) testing for those patients suspected of having syphilis

Electrolyte and Biomarker Studies

Electrolytes

References

↑ Weytingh MD, Bossuyt PM, van Crevel H (July 1995). "Reversible dementia: more than 10% or less than 1%? A quantitative review". J Neurol. 242 (7): 466–71. doi:10.1007/BF00873551. PMID 7595679.
↑ Knopman DS, Petersen RC, Cha RH, Edland SD, Rocca WA (February 2006). "Incidence and causes of nondegenerative nonvascular dementia: a population-based study". Arch Neurol. 63 (2): 218–21. doi:10.1001/archneur.63.2.218. PMID 16476810.
↑ Knopman DS, DeKosky ST, Cummings JL, Chui H, Corey-Bloom J, Relkin N, Small GW, Miller B, Stevens JC (May 2001). "Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology". Neurology. 56 (9): 1143–53. doi:10.1212/wnl.56.9.1143. PMID 11342678.

Template:WH Template:WS

[pmid7595679-1] Weytingh MD, Bossuyt PM, van Crevel H (July 1995). "Reversible dementia: more than 10% or less than 1%? A quantitative review". J Neurol. 242 (7): 466–71. doi:10.1007/BF00873551. PMID 7595679.

[pmid16476810-2] Knopman DS, Petersen RC, Cha RH, Edland SD, Rocca WA (February 2006). "Incidence and causes of nondegenerative nonvascular dementia: a population-based study". Arch Neurol. 63 (2): 218–21. doi:10.1001/archneur.63.2.218. PMID 16476810.

[pmid11342678-3] Knopman DS, DeKosky ST, Cummings JL, Chui H, Corey-Bloom J, Relkin N, Small GW, Miller B, Stevens JC (May 2001). "Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology". Neurology. 56 (9): 1143–53. doi:10.1212/wnl.56.9.1143. PMID 11342678.

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@@ Line 2: / Line 2: @@
 {{Template:Dementia}}
 {{CMG}}
-== Laboratory Findings ==
-* [[Complete blood count]] ([[CBC]])
-* Toxicology screening
-* [[Liver function test]]s ([[LFT]]s)
-* [[Calcium]]
-* [[Blood urea nitrogen]] ([[BUN]]) / [[creatinine]]
-* [[Glucose]]
-* [[Thyroid function test]]s
-* [[Vitamin B12]] levels
-* [[Folate]] levels
-* Infectious/inflammatory screenings
-* [[HIV test]]ing for suspected patients
-* [[Rapid plasma reagin]] (RPR) testing for those patients suspected of having [[syphilis]]
-=== Electrolyte and Biomarker Studies ===
+==Overview==
-* [[Electrolyte]]s
+Limited laboratory testing is recommended in most patients being evaluated for cognitive impairment and dementia. We do not order other laboratory tests unless there is a specific suspicion for abnormality. Other than the routine lab work for dementia, other laboratory tests are not recommended unless there is a specific suspicion for abnormality.<ref name="pmid7595679">{{cite journal |vauthors=Weytingh MD, Bossuyt PM, van Crevel H |title=Reversible dementia: more than 10% or less than 1%? A quantitative review |journal=J Neurol |volume=242 |issue=7 |pages=466–71 |date=July 1995 |pmid=7595679 |doi=10.1007/BF00873551 |url=}}</ref><ref name="pmid16476810">{{cite journal |vauthors=Knopman DS, Petersen RC, Cha RH, Edland SD, Rocca WA |title=Incidence and causes of nondegenerative nonvascular dementia: a population-based study |journal=Arch Neurol |volume=63 |issue=2 |pages=218–21 |date=February 2006 |pmid=16476810 |doi=10.1001/archneur.63.2.218 |url=}}</ref>
+==Laboratory Findings==
+Routine lab work for dementias include:
+*[[Complete blood count]] ([[CBC]])
+*Toxicology screening
+*[[Liver function test]]s ([[LFT]]s)
+*[[Calcium]]
+*[[Blood urea nitrogen]] ([[BUN]]) / [[creatinine]]
+*[[Glucose]]
+*[[Thyroid function test]]s
+*[[Vitamin B12]] levels<ref name="pmid11342678">{{cite journal |vauthors=Knopman DS, DeKosky ST, Cummings JL, Chui H, Corey-Bloom J, Relkin N, Small GW, Miller B, Stevens JC |title=Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology |journal=Neurology |volume=56 |issue=9 |pages=1143–53 |date=May 2001 |pmid=11342678 |doi=10.1212/wnl.56.9.1143 |url=}}</ref>
+*[[Folate]] levels
+*Infectious/inflammatory screenings
+*[[HIV test]]ing for suspected patients
+*[[Rapid plasma reagin]] (RPR) testing for those patients suspected of having [[syphilis]]
+===Electrolyte and Biomarker Studies===
+*[[Electrolyte]]s
 ==References==
 {{reflist|2}}
-[[Category:Signs and symptoms]]
+{{WH}}
+{{WS}}
 [[Category:Neurology]]
 [[Category:Psychiatry]]
-[[Category:Primary care]]
 [[Category:Needs overview]]
-{{WH}}
-{{WS}}