WBR0337: Difference between revisions
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{{WBRQuestion | {{WBRQuestion | ||
|QuestionAuthor={{YD}} (Reviewed by {{YD}} and {{AJL}}) | |QuestionAuthor= {{YD}} (Reviewed by {{YD}} and {{AJL}}) | ||
|ExamType=USMLE Step 1 | |ExamType=USMLE Step 1 | ||
|MainCategory=Physiology | |MainCategory=Physiology | ||
Line 22: | Line 22: | ||
|SubCategory=Genitourinary | |SubCategory=Genitourinary | ||
|Prompt=During development, in-utero testosterone secretion by the testes act directly on the Wolffian ducts and play an important role in the differentiation of external and internal male organs. Similarly, dihydrotestosterone (DHT), a more potent androgen derived from testosterone by the action of 5-alpha-reductase, is also involved in the differentiation of male organs. Which of the following processes is a function of DHT? | |Prompt=During development, in-utero testosterone secretion by the testes act directly on the Wolffian ducts and play an important role in the differentiation of external and internal male organs. Similarly, dihydrotestosterone (DHT), a more potent androgen derived from testosterone by the action of 5-alpha-reductase, is also involved in the differentiation of male organs. Which of the following processes is a function of DHT? | ||
|Explanation=In males, testosterone is involved in the differentiation of internal genitalia (excluding the prostate), voice deepening, and closure of the epiphyseal plates of bones. The action of testosterone also includes the growth spurt at puberty, which includes the pubertal growth of the penis, seminal vesicles, and production of sperm. On the other hand, dihydrotestosterone (DHT) is involved early in the differentiation of the external genitalia | |Explanation=In males, testosterone is involved in the differentiation of internal genitalia (excluding the prostate), voice deepening, and closure of the epiphyseal plates of bones. The action of testosterone also includes the growth spurt at puberty, which includes the pubertal growth of the penis, seminal vesicles, and production of sperm. On the other hand, dihydrotestosterone (DHT) is involved early in the differentiation of the external genitalia (penis and scrotum) and the prostate. Later in life, DHT is involved in the growth of the prostate, male-pattern balding, and the activity of sebaceous glands.<br> | ||
[[Image:Function of male sex hormones testosterone DHT dihydrotestosterone comparison table.png|500px]] | |||
|AnswerA=Differentiation of the epididymis | |AnswerA=Differentiation of the epididymis | ||
|AnswerAExp=Differentiation of the epididymis is a function of testosterone. | |AnswerAExp=Differentiation of the epididymis is a function of testosterone. | ||
|AnswerB=Differentiation of the vas deferens | |AnswerB=Differentiation of the vas deferens | ||
|AnswerBExp=Differentiation of the vas deferens is | |AnswerBExp=Differentiation of the vas deferens is a function of testosterone. | ||
|AnswerC=Closure of the epiphyseal plate | |AnswerC=Closure of the epiphyseal plate | ||
|AnswerCExp=Closure of the epiphyseal plate is | |AnswerCExp=Closure of the epiphyseal plate of bone is a function of testosterone. | ||
|AnswerD=Differentiation of the prostate gland | |AnswerD=Differentiation of the prostate gland | ||
|AnswerDExp=Differentiation of the prostate gland is | |AnswerDExp=Differentiation of the prostate gland is a function of DHT. | ||
|AnswerE=Pubertal voice deepening | |AnswerE=Pubertal voice deepening | ||
|AnswerEExp=Pubertal voice deepening is | |AnswerEExp=Pubertal voice deepening is a function of testosterone. | ||
|EducationalObjectives=DHT is involved in the differentiation of the external genitalia | |EducationalObjectives=DHT is involved in the differentiation of the prostate and the external genitalia (penis and scrotum) | ||
|References=First Aid 2014 page | |References=First Aid 2014 page 573 | ||
|RightAnswer=D | |RightAnswer=D | ||
|WBRKeyword=Differentiation, sex organs, testosterone, DHT, dihydrotestosterone, epididymis, vas deferens, genitals, genitalia, puberty, pubertal, penis, sperm, sebaceous, hormone, hormones | |WBRKeyword=Differentiation, sex organs, testosterone, DHT, dihydrotestosterone, epididymis, vas deferens, genitals, genitalia, puberty, pubertal, penis, sperm, sebaceous, hormone, hormones | ||
|Approved=Yes | |Approved=Yes | ||
}} | }} |
Latest revision as of 00:13, 28 October 2020
Author | [[PageAuthor::Yazan Daaboul, M.D. (Reviewed by Yazan Daaboul, M.D. and Alison Leibowitz [1])]] |
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Exam Type | ExamType::USMLE Step 1 |
Main Category | MainCategory::Physiology |
Sub Category | SubCategory::Genitourinary |
Prompt | [[Prompt::During development, in-utero testosterone secretion by the testes act directly on the Wolffian ducts and play an important role in the differentiation of external and internal male organs. Similarly, dihydrotestosterone (DHT), a more potent androgen derived from testosterone by the action of 5-alpha-reductase, is also involved in the differentiation of male organs. Which of the following processes is a function of DHT?]] |
Answer A | AnswerA::Differentiation of the epididymis |
Answer A Explanation | AnswerAExp::Differentiation of the epididymis is a function of testosterone. |
Answer B | AnswerB::Differentiation of the vas deferens |
Answer B Explanation | AnswerBExp::Differentiation of the vas deferens is a function of testosterone. |
Answer C | AnswerC::Closure of the epiphyseal plate |
Answer C Explanation | AnswerCExp::Closure of the epiphyseal plate of bone is a function of testosterone. |
Answer D | AnswerD::Differentiation of the prostate gland |
Answer D Explanation | AnswerDExp::Differentiation of the prostate gland is a function of DHT. |
Answer E | AnswerE::Pubertal voice deepening |
Answer E Explanation | AnswerEExp::Pubertal voice deepening is a function of testosterone. |
Right Answer | RightAnswer::D |
Explanation | [[Explanation::In males, testosterone is involved in the differentiation of internal genitalia (excluding the prostate), voice deepening, and closure of the epiphyseal plates of bones. The action of testosterone also includes the growth spurt at puberty, which includes the pubertal growth of the penis, seminal vesicles, and production of sperm. On the other hand, dihydrotestosterone (DHT) is involved early in the differentiation of the external genitalia (penis and scrotum) and the prostate. Later in life, DHT is involved in the growth of the prostate, male-pattern balding, and the activity of sebaceous glands.
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Approved | Approved::Yes |
Keyword | WBRKeyword::Differentiation, WBRKeyword::sex organs, WBRKeyword::testosterone, WBRKeyword::DHT, WBRKeyword::dihydrotestosterone, WBRKeyword::epididymis, WBRKeyword::vas deferens, WBRKeyword::genitals, WBRKeyword::genitalia, WBRKeyword::puberty, WBRKeyword::pubertal, WBRKeyword::penis, WBRKeyword::sperm, WBRKeyword::sebaceous, WBRKeyword::hormone, WBRKeyword::hormones |
Linked Question | Linked:: |
Order in Linked Questions | LinkedOrder:: |