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{{WBRQuestion
{{WBRQuestion
|QuestionAuthor={{Rim}}
|QuestionAuthor= {{YD}} (Reviewed by  {{YD}})
|ExamType=USMLE Step 1
|ExamType=USMLE Step 1
|MainCategory=Anatomy
|MainCategory=Anatomy
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|MainCategory=Anatomy
|MainCategory=Anatomy
|SubCategory=Cardiology
|SubCategory=Cardiology
|MainCategory=Anatomy
|MainCategory=Anatomy
|MainCategory=Anatomy
|MainCategory=Anatomy
|MainCategory=Anatomy
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|MainCategory=Anatomy
|MainCategory=Anatomy
|SubCategory=Cardiology
|SubCategory=Cardiology
|Prompt=A 56 year old male patient presents to the emergency department with chest pain and shortness of breath. Appropriate work-up is rapidly initiated.  Patient’s blood work-up reveals elevated levels of Troponin. His electrocardiogram (ECG) shows ST-segment elevation in more than one lead.  The diagnosis of ST-elevation myocardial infarction (STEMI) is made. Cardiac catheterization shows occlusion of the right coronary artery (RCA). Which of the following components of the heart is most likely to be affected as a result of the patient’s STEMI?
|Prompt=A 56-year-old man presents to the emergency department (ED) with complaints of chest pain and shortness of breath. On arrival, and ECG demonstrates ST-segment elevation in 2 consecutive leads, and blood work-up is remarkable for elevated serum troponin concentration. The diagnosis of STEMI is made, and the patient is transferred to the cardiac catheterization lab for an emergent percutaneous coronary intervention (PCI). Cardiac catheterization reveals a total occlusion of the right coronary artery (RCA). Which of the following anatomical locations of the heart is most likely affected as a result of this patient’s STEMI?
|Explanation=The [[cardiac circulation]] is characterized by 2 main arteries that contain several branches as they descend from their sinuses at the base of the aorta.  They are the [[left main artery]] and the [[right coronary artery]] ([[RCA]]). The [[left main artery]] is further divided into the [[left anterior descending]] ([[LAD]]) artery, also called the “widow maker” because it is the most severe and the most common artery to be occluded in [[myocardial infarction]] and subsequent death, and the [[Left circumflex]] (LCx) artery.  The LCx gives rise to the [[posterior descending artery]] (PDA) in approximately 35% of the case. 
|Explanation=There are two main epicardial arteries that supply the myocardium: the left coronary artery (LCA) and the right coronary artery (RCA). The heart is supplied by these two arteries and their branches in such a way that the LCA supplies mainly the left ventricle, whereas the RCA supplies the right atrium and ventricle, the SA node, the inferior wall, posterior interventricular septum, and posteromedial papillary muscle in approximately 85 % of the cases.  
On the other hand, the RCA gives rise to the PDA in more than 65% of the cases.  The RCA supplies the [[SA node]].


Educational Objective:
The RCA originates above the right cusp of the aortic valve. It travels down the right atrioventricular groove, towards the crux of the heart. In addition to supplying blood to the right ventricle (RV), the RCA supplies 25% to 35% of the left ventricle (LV). The LCA normally arises from the aortic sinus above the left cusp of the aortic valve and supplies the majority of the blood flow to the left ventricle. In fact, the LCA supplies the posterolateral side of the LV as well as the anterior part of the LV, which includes the anterolateral myocardium, the apex, the anterior interventricular septum, and the anterolateral papillary muscle.  
The right coronary artery (RCA) is the most common arterial supply to the sinoatrial (SA) node.


The origin of the LCA is called the left main coronary artery, and it bifurcates into the following two main branches: Left anterior descending (LAD) artery and Left circumflex artery (LCx). The dominance of coronary circulation is determined by the type of arteries that supply the posterior and inferior wall of the left ventricle. The artery that supplies the posterior descending artery (PDA) and the posterolateral artery (PLA) determines the coronary dominance. Approximately 60 - 70% of the general population are right-dominant, 25% are co-dominant, and 15% are left-dominant.
|AnswerA=Anterior interventricular septum
|AnswerA=Anterior interventricular septum
|AnswerAExp=Blood supply to the anterior interventricular septum is most commonly from the LAD
|AnswerAExp=The LAD usually provides the blood supply to the anterior interventricular septum.
|AnswerB=Left atrium
|AnswerB=Left atrium
|AnswerBExp=Blood supply to the left atrium is most commonly from the left main coronary artery.
|AnswerBExp=The left main coronary artery usually provides the blood supply to the left atrium.
|AnswerC=Anterolateral papillary muscle
|AnswerC=Anterolateral papillary muscle
|AnswerCExp=The anterior papillary muscle most commonly receives dual blood supply from the LAD and the LCx.
|AnswerCExp=The anterior papillary muscle most commonly receives a dual blood supply from the LAD and the LCx.
|AnswerD=Sinoatrial (SA) node
|AnswerD=Sinoatrial (SA) node
|AnswerDExp=Blood supply to the SA node is most commonly from the RCA.
|AnswerDExp=The RCA usually provides the blood supply to the SA node.
|AnswerE=Apex
|AnswerE=Apex
|AnswerEExp=The apex of the heart receives dual supply from the LAD and the PDA. The LDA provides most of the blood supply to the apex.  
|AnswerEExp=The apex of the heart receives a dual blood supply from the LAD and the PDA. The LDA provides the majority of the blood supply to the apex.
|EducationalObjectives=The heart is supplied by these two arteries and their branches in such a way that the LCA supplies mainly the left ventricle, whereas the RCA supplies the right atria and ventricle, the SA node, the inferior wall, posterior interventricular septum, and posteromedial papillary muscle in 85 % of the cases.
|References=First Aid 2014 page 266
|RightAnswer=D
|RightAnswer=D
|WBRKeyword=coronary, artery, sinoatrial, node, sinoatrial node, SA, right, blood, supply
|WBRKeyword=Coronary artery, Sinoatrial node, SA, blood supply, cardiovascular system, cardiology,
|Approved=No
|Approved=Yes
}}
}}

Latest revision as of 00:38, 28 October 2020

 
Author [[PageAuthor::Yazan Daaboul, M.D. (Reviewed by Yazan Daaboul, M.D.)]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Anatomy
Sub Category SubCategory::Cardiology
Prompt [[Prompt::A 56-year-old man presents to the emergency department (ED) with complaints of chest pain and shortness of breath. On arrival, and ECG demonstrates ST-segment elevation in 2 consecutive leads, and blood work-up is remarkable for elevated serum troponin concentration. The diagnosis of STEMI is made, and the patient is transferred to the cardiac catheterization lab for an emergent percutaneous coronary intervention (PCI). Cardiac catheterization reveals a total occlusion of the right coronary artery (RCA). Which of the following anatomical locations of the heart is most likely affected as a result of this patient’s STEMI?]]
Answer A AnswerA::Anterior interventricular septum
Answer A Explanation AnswerAExp::The LAD usually provides the blood supply to the anterior interventricular septum.
Answer B AnswerB::Left atrium
Answer B Explanation AnswerBExp::The left main coronary artery usually provides the blood supply to the left atrium.
Answer C AnswerC::Anterolateral papillary muscle
Answer C Explanation AnswerCExp::The anterior papillary muscle most commonly receives a dual blood supply from the LAD and the LCx.
Answer D AnswerD::Sinoatrial (SA) node
Answer D Explanation AnswerDExp::The RCA usually provides the blood supply to the SA node.
Answer E AnswerE::Apex
Answer E Explanation AnswerEExp::The apex of the heart receives a dual blood supply from the LAD and the PDA. The LDA provides the majority of the blood supply to the apex.
Right Answer RightAnswer::D
Explanation [[Explanation::There are two main epicardial arteries that supply the myocardium: the left coronary artery (LCA) and the right coronary artery (RCA). The heart is supplied by these two arteries and their branches in such a way that the LCA supplies mainly the left ventricle, whereas the RCA supplies the right atrium and ventricle, the SA node, the inferior wall, posterior interventricular septum, and posteromedial papillary muscle in approximately 85 % of the cases.

The RCA originates above the right cusp of the aortic valve. It travels down the right atrioventricular groove, towards the crux of the heart. In addition to supplying blood to the right ventricle (RV), the RCA supplies 25% to 35% of the left ventricle (LV). The LCA normally arises from the aortic sinus above the left cusp of the aortic valve and supplies the majority of the blood flow to the left ventricle. In fact, the LCA supplies the posterolateral side of the LV as well as the anterior part of the LV, which includes the anterolateral myocardium, the apex, the anterior interventricular septum, and the anterolateral papillary muscle.

The origin of the LCA is called the left main coronary artery, and it bifurcates into the following two main branches: Left anterior descending (LAD) artery and Left circumflex artery (LCx). The dominance of coronary circulation is determined by the type of arteries that supply the posterior and inferior wall of the left ventricle. The artery that supplies the posterior descending artery (PDA) and the posterolateral artery (PLA) determines the coronary dominance. Approximately 60 - 70% of the general population are right-dominant, 25% are co-dominant, and 15% are left-dominant.
Educational Objective: The heart is supplied by these two arteries and their branches in such a way that the LCA supplies mainly the left ventricle, whereas the RCA supplies the right atria and ventricle, the SA node, the inferior wall, posterior interventricular septum, and posteromedial papillary muscle in 85 % of the cases.
References: First Aid 2014 page 266]]

Approved Approved::Yes
Keyword WBRKeyword::Coronary artery, WBRKeyword::Sinoatrial node, WBRKeyword::SA, WBRKeyword::blood supply, WBRKeyword::cardiovascular system, WBRKeyword::cardiology
Linked Question Linked::
Order in Linked Questions LinkedOrder::