Cellulitis cost-effectiveness of therapy: Difference between revisions
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The use of prophylactic antibiotic therapy to prevent the recurrence of cellulitis was shown to be cost-effective. Low dose penicillin serves to prevent future attacks and offers no significant increase in cost. | The use of prophylactic antibiotic therapy to prevent the recurrence of cellulitis was shown to be cost-effective. Low dose penicillin serves to prevent future attacks and offers no significant increase in cost. <ref name="pmid10585800">{{cite journal| author=Perl B, Gottehrer NP, Raveh D, Schlesinger Y, Rudensky B, Yinnon AM| title=Cost-effectiveness of blood cultures for adult patients with cellulitis. | journal=Clin Infect Dis | year= 1999 | volume= 29 | issue= 6 | pages= 1483-8 | pmid=10585800 | doi=10.1086/313525 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10585800 }} </ref> | ||
A study done in a pediatric population comparing intravenous antibiotic treatment at home versus in the hospital setting showed the former as the more effective and less costly option. | A study done in a pediatric population comparing intravenous antibiotic treatment at home versus in the hospital setting showed the former as the more effective and less costly option. <ref name="pmid31420293">{{cite journal| author=Oppong R, Kodabuckus S| title=Cost-effectiveness of outpatient parenteral antibiotic therapy for children with cellulitis. | journal=Lancet Infect Dis | year= 2019 | volume= 19 | issue= 10 | pages= 1041-1042 | pmid=31420293 | doi=10.1016/S1473-3099(19)30413-X | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31420293 }} </ref> <ref name="pmid31420292">{{cite journal| author=Ibrahim LF, Huang L, Hopper SM, Dalziel K, Babl FE, Bryant PA| title=Intravenous ceftriaxone at home versus intravenous flucloxacillin in hospital for children with cellulitis: a cost-effectiveness analysis. | journal=Lancet Infect Dis | year= 2019 | volume= 19 | issue= 10 | pages= 1101-1108 | pmid=31420292 | doi=10.1016/S1473-3099(19)30288-9 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31420292 }} </ref> | ||
With regard to diagnostic modalities, blood cultures have been shown to be of low yield, with minimal impact on clinical management, thereby not cost-effective for most patients. | With regard to diagnostic modalities, blood cultures have been shown to be of low yield, with minimal impact on clinical management, thereby not cost-effective for most patients. <ref name="pmid24551029">{{cite journal| author=Mason JM, Thomas KS, Crook AM, Foster KA, Chalmers JR, Nunn AJ | display-authors=etal| title=Prophylactic antibiotics to prevent cellulitis of the leg: economic analysis of the PATCH I & II trials. | journal=PLoS One | year= 2014 | volume= 9 | issue= 2 | pages= e82694 | pmid=24551029 | doi=10.1371/journal.pone.0082694 | pmc=3925077 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24551029 }} </ref> | ||
==References== | ==References== | ||
Latest revision as of 07:19, 1 December 2020
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The use of prophylactic antibiotic therapy to prevent the recurrence of cellulitis was shown to be cost-effective. Low dose penicillin serves to prevent future attacks and offers no significant increase in cost. [1]
A study done in a pediatric population comparing intravenous antibiotic treatment at home versus in the hospital setting showed the former as the more effective and less costly option. [2] [3]
With regard to diagnostic modalities, blood cultures have been shown to be of low yield, with minimal impact on clinical management, thereby not cost-effective for most patients. [4]
References
- ↑ Perl B, Gottehrer NP, Raveh D, Schlesinger Y, Rudensky B, Yinnon AM (1999). "Cost-effectiveness of blood cultures for adult patients with cellulitis". Clin Infect Dis. 29 (6): 1483–8. doi:10.1086/313525. PMID 10585800.
- ↑ Oppong R, Kodabuckus S (2019). "Cost-effectiveness of outpatient parenteral antibiotic therapy for children with cellulitis". Lancet Infect Dis. 19 (10): 1041–1042. doi:10.1016/S1473-3099(19)30413-X. PMID 31420293.
- ↑ Ibrahim LF, Huang L, Hopper SM, Dalziel K, Babl FE, Bryant PA (2019). "Intravenous ceftriaxone at home versus intravenous flucloxacillin in hospital for children with cellulitis: a cost-effectiveness analysis". Lancet Infect Dis. 19 (10): 1101–1108. doi:10.1016/S1473-3099(19)30288-9. PMID 31420292.
- ↑ Mason JM, Thomas KS, Crook AM, Foster KA, Chalmers JR, Nunn AJ; et al. (2014). "Prophylactic antibiotics to prevent cellulitis of the leg: economic analysis of the PATCH I & II trials". PLoS One. 9 (2): e82694. doi:10.1371/journal.pone.0082694. PMC 3925077. PMID 24551029.