Dermatitis herpetiformis history and symptoms: Difference between revisions

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Latest revision as of 01:02, 7 February 2021

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Vishnu Vardhan Serla M.B.B.S. [2]

Overview

Dermatitis Herpetiformis (also called Duhring's disease), is a chronic itchy rash which is frequently associated with Celiac Disease. The rash is made of papules and vesicles which are present on different parts of the body mostly commonly on neck, trunk, buttocks and knees. It is an autoimmune mediated skin condition, which is IgA mediated reaction and is associated with gluten sensitivity of small bowel. There is presence of antibodies which leads to positive serology test results.

Dermatitis herpetiformis is associated with high prevalence of other autoimmune diseases.

History

The patients with dermatitis herpetiformis will have a history of:

Papulovesicular skin rash.
gluten insensitivity.
Family history of Celiac disease.
Autoimmune Thyroid disease and other autoimmune disease.

Symptoms

Rash on the extensor surfaces of skin
Diarrhea due to inflammation of the small intestine.

References

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 ==Overview==
-Dermatitis herpetiformis breakouts are usually extremely itchy.  In many people the [[Vesicle (Biology)|vesicles]] or [[papule]]s appear on the elbows, knees, back, and buttocks (pressure points).   It may also present as a patch of red skin with little water blisters scattered about.   It is a systemic condition; the unpredictable skin rash may appear or be exacerbated by any irritation such as dry skin, scratching or clothing that is rough or scratchy.   The fact that the rash is most prevalent at pressure points (where clothing rubs the most) may be why the symptoms sometimes appear to be symmetrical.<ref>Clarindo MV, Possebon AT, Soligo EM, Uyeda H, Ruaro RT, Empinotti JC. Dermatitis herpetiformis: pathophysiology, clinical presentation, diagnosis and treatment. An Bras Dermatol. 2014;89(6):865-877. doi:10.1590/abd1806-4841.20142966</ref>
+Dermatitis Herpetiformis (also called [[Duhring's disease]]), is a chronic itchy rash which is frequently associated with [[Celiac Disease]]. The rash is made of [[papules]] and [[vesicles]] which are present on different parts of the body mostly commonly on neck, trunk, buttocks and knees. It is an [[autoimmune]] mediated skin condition, which is IgA mediated reaction and is associated with [[gluten sensitivity]] of small bowel. There is presence of [[antibodies]] which leads to positive serology test results.
+Dermatitis herpetiformis is associated with high prevalence of other [[autoimmune diseases]].
 ==History==