Immune Thrombocytopenia risk factors: Difference between revisions
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OR | OR | ||
The most potent risk factor in the development of | The most potent risk factor in the development of ITP is [risk factor 1]. Other risk factors include [risk factor 2], [risk factor 3], and [risk factor 4]. | ||
OR | OR | ||
Common risk factors in the development of | Common risk factors in the development of ITP include environmental, genetic and viral. Genetic risk factors includes mutations in single nucleotide polymorphism and variety of interleukins. The most common viral and environmental risk factors include infection with HIV and Helicobacter pylori. | ||
OR | OR | ||
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Common risk factors in the development of [disease name] include [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4]. | Common risk factors in the development of [disease name] include [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4]. | ||
===Common Risk Factors=== | ===Common Risk Factors=== | ||
*Common risk factors in the development of | |||
*Common risk factors in the development of | *Common risk factors in the development of Immune thrombocytopenia may be environmental, genetic, and viral. | ||
** | *Genetic risk factors include: | ||
** | ***association between ITP and single nucleotide polymorphism (SNP) | ||
**[ | ***[[Polymorphism]] in genes of [[Interleukin 1|Interleukin-1]], [[IL-2]], [[IL-4]], [[IL-6]], [[IL-10]], [[IL-17]], [[TNF-alpha|TNF-<math>\alpha</math>]], [[Tumor necrosis factor-beta|TNF-<math>\beta</math>]] and [[Interferon-beta|INF-<math>\gamma</math>.]] <ref name="pmidhttps://doi.org/10.3389/fimmu.2018.00880">{{cite journal| author=Schmoldt A, Benthe HF, Haberland G| title=Digitoxin metabolism by rat liver microsomes. | journal=Biochem Pharmacol | year= 1975 | volume= 24 | issue= 17 | pages= 1639-41 | pmid=https://doi.org/10.3389/fimmu.2018.00880 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10 }}</ref> | ||
*Environmental and viral risk factors include exposure with [[Human Immunodeficiency Virus (HIV)|HIV]], [[Helicobacter pylori]], HCV, [[Cytomegalovirus infection|CMV]], and [[EBV.]] | |||
*Common non-modifiable risk factors in the development of Immune thrombocytopenia in children include: | |||
**older age | |||
**less thrombocytopenia at the initial diagnosis | |||
**gradual onset of symptoms | |||
**lack of platelet count recovery at four weeks | |||
**lack of proceeding infection or [[vaccination]] as a trigger.<ref name="KohliChaturvedi2019">{{cite journal|last1=Kohli|first1=Rahil|last2=Chaturvedi|first2=Shruti|title=Epidemiology and Clinical Manifestations of Immune Thrombocytopenia|journal=Hämostaseologie|volume=39|issue=03|year=2019|pages=238–249|issn=0720-9355|doi=10.1055/s-0039-1683416}}</ref> | |||
===Less Common Risk Factors=== | ===Less Common Risk Factors=== | ||
*Less common risk factors in the development of [disease name] include: | *Less common risk factors in the development of [disease name] include: | ||
**[Risk factor 1] | **[Risk factor 1] | ||
Latest revision as of 18:03, 8 February 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maryam Barkhordarian, M.D.[2]
Overview
There are no established risk factors for [disease name].
OR
The most potent risk factor in the development of ITP is [risk factor 1]. Other risk factors include [risk factor 2], [risk factor 3], and [risk factor 4].
OR
Common risk factors in the development of ITP include environmental, genetic and viral. Genetic risk factors includes mutations in single nucleotide polymorphism and variety of interleukins. The most common viral and environmental risk factors include infection with HIV and Helicobacter pylori.
OR
Common risk factors in the development of [disease name] may be occupational, environmental, genetic, and viral.
Risk Factors
There are no established risk factors for [disease name].
OR
The most potent risk factor in the development of [disease name] is [risk factor 1]. Other risk factors include [risk factor 2], [risk factor 3], and [risk factor 4].
OR
Common risk factors in the development of [disease name] include [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].
Common Risk Factors
- Common risk factors in the development of Immune thrombocytopenia may be environmental, genetic, and viral.
- Genetic risk factors include:
- association between ITP and single nucleotide polymorphism (SNP)
- Polymorphism in genes of Interleukin-1, IL-2, IL-4, IL-6, IL-10, IL-17, TNF-<math>\alpha</math>, TNF-<math>\beta</math> and INF-<math>\gamma</math>. [1]
- Environmental and viral risk factors include exposure with HIV, Helicobacter pylori, HCV, CMV, and EBV.
- Common non-modifiable risk factors in the development of Immune thrombocytopenia in children include:
- older age
- less thrombocytopenia at the initial diagnosis
- gradual onset of symptoms
- lack of platelet count recovery at four weeks
- lack of proceeding infection or vaccination as a trigger.[2]
Less Common Risk Factors
- Less common risk factors in the development of [disease name] include:
- [Risk factor 1]
- [Risk factor 2]
- [Risk factor 3]
References
- ↑ Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes" Check
|url=value (help). Biochem Pharmacol. 24 (17): 1639–41. PMID https://doi.org/10.3389/fimmu.2018.00880 Check|pmid=value (help). - ↑ Kohli, Rahil; Chaturvedi, Shruti (2019). "Epidemiology and Clinical Manifestations of Immune Thrombocytopenia". Hämostaseologie. 39 (03): 238–249. doi:10.1055/s-0039-1683416. ISSN 0720-9355.