Disease Name differential diagnosis: Difference between revisions

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[[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Single-page_with_differential_diagnosis_table]]


{{CMG}}; {{AE}}{{TAM}}
{{CMG}}; {{AE}} {{MMT}}


==Overview==
==Overview==
COVID-19-associated hepatic Injury must be differentiated from other conditions that may cause elevation of [[liver enzymes]].
Adhesive capsulitis is one of the most common disease in primary care settings. It can be occurred primarily or secondarily. Careful clinical examination and diagnosis is need to differentiate it from other disease.  


==Differential Diagnosis==
==Differential Diagnosis==
 
Adhesive capsulitis is one of the most common disease in primary care settings. It can be occurred primarily or secondarily. Careful clinical examination and diagnosis is need to differentiate it from other disease. Differentials are<ref name="pmid30811157">{{cite journal |vauthors=Ramirez J |title=Adhesive Capsulitis: Diagnosis and Management |journal=Am Fam Physician |volume=99 |issue=5 |pages=297–300 |date=March 2019 |pmid=30811157 |doi= |url=}}</ref><ref name="urlAdhesive Capsulitis - StatPearls - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK532955/ |title=Adhesive Capsulitis - StatPearls - NCBI Bookshelf |format= |work= |accessdate=}}</ref>:
COVID-19-associated hepatic Injury must be differentiated from other conditions that may cause elevation of [[liver enzymes]].
*Rotator cuff injury or tendinopathy +/- supraspinatus impingement: History of overuse or repetitive use with focal tenderness and preservation of passive range of motion helps to aid diagnosis of rotator cuff tendinopathy. hawkin and neer test positive in impingement.
{|
*Rotator cuff tear: Severe lateral arm pain with limited active and passive range of motion with drop arm test positive. MRI help to diagnose it.
|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
*Acromioclavicular arthropathy: Pain at superior location of shoulder joint with history of heay weight lifting or overuse with preservation of range of motion. It can be diagnose clinically with positive result of cross arm test and compression test.
! colspan="2" rowspan="3" align="center" style="background:#4479BA; color: #FFFFFF;" |Disease
*Subacromion Bursitis: Local injection of lidocaine and MRI aid the diagnosis.
! colspan="5" align="center" style="background:#4479BA; color: #FFFFFF;" |Clinical manifestations
*Cervical Radiculopathy or Cervical disc degeneration: Weakness and numbness impaired light touch in upper extremity with reduced active range of motion with neck movement.
! colspan="3" align="center" style="background:#4479BA; color: #FFFFFF;" |Laboratory findings
*Subdeltoid Bursitis: History of overuse injury and MRI aid in diagnose this.
! rowspan="3" align="center" style="background:#4479BA; color: #FFFFFF;" |Additional findings
*Tendinopathy of biceps at bicipital groove: anterior upper arm pain with positive test result of speed and yergason test, MRI rule out the adhesive capsulitis.
|-
*Malignancy: Constitutional symptoms and compressional symptoms from pancoast tumor  with imaging technique rule out frozen shoulder.
! colspan="3" align="center" style="background:#4479BA; color: #FFFFFF;" |Symptoms
*Polymyalgia Rheumatica: Proximal muscle weakness of upper and lower extremity and increased ESR rule out adhesive capsulitis.
! colspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Signs
*Autoimmune disease: SLE or Rheumatoid Arthritis or other autoimmune disease may mimic frozen shoulder.
! rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Transaminitis (elevated AST and ALT)
! rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Viral markers
! rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Autoimmune markers
|-
! align="center" style="background:#4479BA; color: #FFFFFF;" |Nausea & vomiting
! align="center" style="background:#4479BA; color: #FFFFFF;" |Abdominal pain
! align="center" style="background:#4479BA; color: #FFFFFF;" |Arthralgia
! align="center" style="background:#4479BA; color: #FFFFFF;" |Jaundice
! align="center" style="background:#4479BA; color: #FFFFFF;" |Hepatomegaly
|-
| rowspan="6" style="background:#4479BA; color: #FFFFFF" |Acute viral hepatitis
| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Hepatitis A]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +++
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ++
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +++
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +++
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[HAV]] Ab
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ---
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Fecal-oral transmission
* Usually acute and self limit
* [[Fever]] usually present
|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Hepatitis B]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +++
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ++
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ++
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +++
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +++
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |HBs Ag, HBc Ab, HBe Ag
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ---
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Percutaneous transmission most common
* May cause acute hepatic failure  or may become chronic
* [[Fever]] usually present
|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Hepatitis C]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +++
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |HCV Ab
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>---</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Percutaneous transmission is most common
* Higher rate of chronic progression
* Associated with extra hepatic manifestation such as [[cryoglobulinemia]] and [[membranoproliferative glomerulonephritis]]
* [[Fever]] usually present
|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Hepatitis E]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+/-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |HEV Ab
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>---</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Fecal-oral transmission
* May cause fulminant disease in pregnancy
* [[Fever]] usually present
|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Cytomegalovirus infection natural history, complications and prognosis|CMV hepatitis]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+/-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |CMV-specific immunoglobulin (Ig)M antibody
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>--</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Usually manifests as mononucleosis syndrome
* [[fever]] usually present
|-
| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[EBV]] hepatitis
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+/-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+/-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Antibody|Heterophile antibody test]], monospot test
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>--</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Systemic manifestations as mononucleosis syndrome
* Fever usually present
|-
| colspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Autoimmune hepatitis
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+/-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>---</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Antinuclear antibodies|ANA]], [[Anti-SM antibody|ASMA]], anti SLA/LP, [[ANCA]], ALKM-1 antibodies
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Liver biopsy may be required for diagnosis
|-
| colspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Alcoholic hepatitis
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+/-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Aspartate transaminase|AST]]>[[Alanine transaminase|ALT]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ---
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>---</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* History of alcohol intake
|-
| colspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Drug induced hepatitis
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+/-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>---</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>---</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* May cause either cholestatic or hepatocellular injury
|-
| colspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Drug
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+/-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>++</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>---</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>---</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* May cause either cholestatic or hepatocellular injury
|}
 


== References ==
== References ==
{{reflist|2}}
{{reflist|2}}

Latest revision as of 20:53, 23 February 2021


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Marufa Marium, M.B.B.S[2]

Overview

Adhesive capsulitis is one of the most common disease in primary care settings. It can be occurred primarily or secondarily. Careful clinical examination and diagnosis is need to differentiate it from other disease.

Differential Diagnosis

Adhesive capsulitis is one of the most common disease in primary care settings. It can be occurred primarily or secondarily. Careful clinical examination and diagnosis is need to differentiate it from other disease. Differentials are[1][2]:

  • Rotator cuff injury or tendinopathy +/- supraspinatus impingement: History of overuse or repetitive use with focal tenderness and preservation of passive range of motion helps to aid diagnosis of rotator cuff tendinopathy. hawkin and neer test positive in impingement.
  • Rotator cuff tear: Severe lateral arm pain with limited active and passive range of motion with drop arm test positive. MRI help to diagnose it.
  • Acromioclavicular arthropathy: Pain at superior location of shoulder joint with history of heay weight lifting or overuse with preservation of range of motion. It can be diagnose clinically with positive result of cross arm test and compression test.
  • Subacromion Bursitis: Local injection of lidocaine and MRI aid the diagnosis.
  • Cervical Radiculopathy or Cervical disc degeneration: Weakness and numbness impaired light touch in upper extremity with reduced active range of motion with neck movement.
  • Subdeltoid Bursitis: History of overuse injury and MRI aid in diagnose this.
  • Tendinopathy of biceps at bicipital groove: anterior upper arm pain with positive test result of speed and yergason test, MRI rule out the adhesive capsulitis.
  • Malignancy: Constitutional symptoms and compressional symptoms from pancoast tumor with imaging technique rule out frozen shoulder.
  • Polymyalgia Rheumatica: Proximal muscle weakness of upper and lower extremity and increased ESR rule out adhesive capsulitis.
  • Autoimmune disease: SLE or Rheumatoid Arthritis or other autoimmune disease may mimic frozen shoulder.

References

  1. Ramirez J (March 2019). "Adhesive Capsulitis: Diagnosis and Management". Am Fam Physician. 99 (5): 297–300. PMID 30811157.
  2. "Adhesive Capsulitis - StatPearls - NCBI Bookshelf".