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| {|
| | __NOTOC__ |
| |- style="background: #4479BA; color: #FFFFFF; text-align: center;"
| |
| ! colspan="2" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
| |
| | colspan="5" |'''Skin examination'''
| |
| ! colspan="2" |Diagnosis
| |
| ! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings
| |
| |-
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Type
| |
| ! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Color
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Texture
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Size
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Distribution
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Dermoscopic Findings
| |
| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology
| |
| |-
| |
| | rowspan="2" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''[[Cutaneous squamous cell carcinoma]]'''
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Squamous cell carcinoma in situ of skin|'''SCC in situ (Bowen's disease''')]]
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Patch
| |
| * Plaque
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Erythematous
| |
| * Skin colored
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Scaly
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Variable
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Fair-skinned individuals: sun-exposed areas
| |
|
| |
|
| * In black individuals: legs, anus, and areas of chronic inflammation
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Presence of dotted and/or glomerular vessels
| |
| * White to yellowish surface scales
| |
| * Red-yellowish background
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Keratinocytic dysplasia of the epidermis
| |
| * No infiltration into dermis
| |
|
| |
|
| * Pleomorphic keratinocytes
| | Cardiac surgery<ref name="pmid23447502">{{cite journal| author=Aya HD, Cecconi M, Hamilton M, Rhodes A| title=Goal-directed therapy in cardiac surgery: a systematic review and meta-analysis. | journal=Br J Anaesth | year= 2013 | volume= 110 | issue= 4 | pages= 510-7 | pmid=23447502 | doi=10.1093/bja/aet020 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23447502 }} </ref> |
| * Hyperchromatic nuclei
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Slow growth over the years
| |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Invasive squamous cell carcinoma'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Papule
| |
| * Plaque
| |
| * Nodule
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Skin colored
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Indurated + hyperkeratotic (well differentiated)
| |
| * Soft + ulceration (poorly differentiated)
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * 0.5 to 1.5 cm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Fair-skinned individuals: sun-exposed areas
| |
| | |
| * In black individuals: legs, anus, and areas of chronic inflammation
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * White circles
| |
| * White structureless areas
| |
| * Masses of keratin
| |
| * Hairpin and linear-irregular vessels
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Keratinocytic dysplasia of the epidermis
| |
| * No infiltration into dermis
| |
| | |
| * Pleomorphic keratinocytes
| |
| * Hyperchromatic nuclei
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * May be painful or pruritic
| |
| |-
| |
| | colspan="2" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''[[Keratoacanthoma]]'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Macule
| |
| * Papule
| |
| * May have telangiectasias
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Skin-colored
| |
| * Mildly erythematous
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Prominent keratinous core in the center of the nodule
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * 1 to 2.5 cm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Sun-exposed areas
| |
| * Face, neck, hands, and arms
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * White circles
| |
| * Keratin
| |
| * Blood spots
| |
| * White structureless zones
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Well-differentiated squamous epithelium
| |
| * Central keratin core
| |
| * Epidermal hyperplasia + large eosinophilic keratinocytes
| |
| | |
| * Dermal inflammatory infiltrate
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Rapid growth (within weeks)
| |
| |-
| |
| | colspan="2" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''[[Merkel cell carcinoma]]'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Intracutaneous nodule
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Shiny
| |
| * Flesh-colored or bluish-red
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Firm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * < 1 cm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Sun-exposed areas
| |
| | |
| * Head and neck
| |
| * Upper limbs and shoulder
| |
| * Lower limbs and hip
| |
| * Trunk
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Milky red areas
| |
| * Linear
| |
| * Irregular vessels
| |
| * Polymorphous vessels
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Uniform cells with large basophilic nuclei
| |
| * Single-cell necrosis
| |
| * Frequent mitoses
| |
| * Lymphovascular invasion
| |
| * Perineural invasion
| |
| * Epidermal involvement via pagetoid spread
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Older individuals with light skin tones
| |
| * Rapidly growing
| |
| |-
| |
| | rowspan="3" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''[[Basal cell carcinoma]]'''
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Nodular basal cell carcinoma]]'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Papule
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Flesh-colored
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Small bump
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Variable
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Face
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Focused, bright red, and branching arborizing vessels
| |
| * Loosely arranged blue-gray dots
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Nest-like infiltration with basaloid cells
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * May have a "rolled" border
| |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Superficial basal cell carcinoma '''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Patch
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Erythematous
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Scaly
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * 1 to > 10 cm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Sun-exposed areas
| |
| * Head (cheek and nose)
| |
| * Trunk
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Superficial fine telangiectasia
| |
| * Shiny white to red, translucent or opaque structureless areas
| |
| * Multiple small erosions
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Large, hyperchromatic, oval nuclei
| |
| * Minimal cytoplasm
| |
| * Small basaloid nodules
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Higher incidence in men
| |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Sclerosing basal cell carcinoma (morpheaform)'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Papule
| |
| | |
| * Plaque
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Flesh-colored
| |
| * Slightly erythematous
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Firm
| |
| * Indurated
| |
| * Indistinct borders
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Variable
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Sun-exposed areas
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Whitish backround
| |
| * Few fine arborizing vessels
| |
| * Multiple brown dots
| |
| * Ulceration
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Thin columns + small nodules
| |
| * Highly collagenized stroma
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Expression of smooth muscle protein alpha-actin in tumor stroma
| |
| |-
| |
| | colspan="2" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''Prurigo nodules'''<ref name="pmid25808786">{{cite journal| author=Errichetti E, Piccirillo A, Stinco G| title=Dermoscopy of prurigo nodularis. | journal=J Dermatol | year= 2015 | volume= 42 | issue= 6 | pages= 632-4 | pmid=25808786 | doi=10.1111/1346-8138.12844 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25808786 }}</ref>
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Dome-shaped nodule
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Flesh-colored
| |
| * Erythematous
| |
| * Brown/black
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Firm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Few millimeters to several centimeters
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Extensor surfaces of the arms and legs and on the trunk
| |
| | |
| * Upper back, abdomen, and sacrum
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * White "starburst pattern" surrounding red/brown/yellow crusts
| |
| * Erosions
| |
| * Hyperkeratosis
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Thick and compact orthohyperkeratosis
| |
| * Irregular epidermal hyperplasia
| |
| * Focal parakeratosis with irregular acanthosis
| |
| * Nonspecific dermal infiltrate containing WBCs
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Nodules range in number from few to hundreds
| |
| * Worsened by heat, sweating, or irritation from clothing
| |
| |-
| |
| | rowspan="6" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''[[Melanoma]]'''
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Melanoma in situ''' (Lentigo Maligna)
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Macule
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Variable (from light to dark brown, black, pink, red, or white)
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Smooth
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Around 1 cm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Sun-damaged skin of the head or neck
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Asymmetric, pigmented follicular openings
| |
| * Gray angulated lines
| |
| * Gray areas, dots, and globules
| |
| * Circle within a circle
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * '''↑''' atypical spindle shaped melanocytes
| |
| * Arranged in single cells or in small nests along the dermoepidermal junction
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Darkening of pigmentation, sharpening of borders, or emergence of nodular areas are signs of progression to lentigo maligna melanoma
| |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Lentigo maligna melanoma]]'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Macule
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Brown/tan
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Freckle-like
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Variable
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Chronically sun-damaged areas
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Asymmetric, pigmented follicular openings
| |
| * Gray angulated lines
| |
| * Gray areas, dots, and globules
| |
| * Circle within a circle
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * "Star-burst giant cells" in epidermis
| |
| * "Swallow's nest" sign along the dermal-epidermal junction
| |
| * Minimal cytoplasm
| |
| * Pale nucleus with small nucleoli
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Usually in older individuals
| |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Superficial spreading melanoma]]'''<ref name="pmid19782937">{{cite journal| author=Argenziano G, Ferrara G, Francione S, Di Nola K, Martino A, Zalaudek I| title=Dermoscopy--the ultimate tool for melanoma diagnosis. | journal=Semin Cutan Med Surg | year= 2009 | volume= 28 | issue= 3 | pages= 142-8 | pmid=19782937 | doi=10.1016/j.sder.2009.06.001 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19782937 }}</ref>
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Macule
| |
| * Plaque with irregular borders
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Variably pigmented (red, blue, black, gray, and white)
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Thin
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * 1 mm to > 1 cm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Anywhere but usually:
| |
| ** Back (men and women)
| |
| ** Lower extremities (women)
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Asymmetry of shape
| |
| * > 2 colors
| |
| * Asymmetry of structures
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Asymmetric
| |
| * Poorly circumscribed
| |
| * Lack cellular maturation
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Lateral (radial) growth before vertical (invasive) growth
| |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Nodular melanoma]]'''<ref name="pmid12734496">{{cite journal| author=Argenziano G, Soyer HP, Chimenti S, Talamini R, Corona R, Sera F et al.| title=Dermoscopy of pigmented skin lesions: results of a consensus meeting via the Internet. | journal=J Am Acad Dermatol | year= 2003 | volume= 48 | issue= 5 | pages= 679-93 | pmid=12734496 | doi=10.1067/mjd.2003.281 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12734496 }}</ref><ref name="MenziesMoloney2013">{{cite journal|last1=Menzies|first1=Scott W.|last2=Moloney|first2=Fergal J.|last3=Byth|first3=Karen|last4=Avramidis|first4=Michelle|last5=Argenziano|first5=Giuseppe|last6=Zalaudek|first6=Iris|last7=Braun|first7=Ralph P.|last8=Malvehy|first8=Josep|last9=Puig|first9=Susana|last10=Rabinovitz|first10=Harold S.|last11=Oliviero|first11=Margaret|last12=Cabo|first12=Horacio|last13=Bono|first13=Riccardo|last14=Pizzichetta|first14=Maria A.|last15=Claeson|first15=Magdalena|last16=Gaffney|first16=Daniel C.|last17=Soyer|first17=H. Peter|last18=Stanganelli|first18=Ignazio|last19=Scolyer|first19=Richard A.|last20=Guitera|first20=Pascale|last21=Kelly|first21=John|last22=McCurdy|first22=Olivia|last23=Llambrich|first23=Alex|last24=Marghoob|first24=Ashfaq A.|last25=Zaballos|first25=Pedro|last26=Kirchesch|first26=Herbert M.|last27=Piccolo|first27=Domenico|last28=Bowling|first28=Jonathan|last29=Thomas|first29=Luc|last30=Terstappen|first30=Karin|last31=Tanaka|first31=Masaru|last32=Pellacani|first32=Giovanni|last33=Pagnanelli|first33=Gianluca|last34=Ghigliotti|first34=Giovanni|last35=Ortega|first35=Blanca Carlos|last36=Crafter|first36=Greg|last37=Ortiz|first37=Ana María Perusquía|last38=Tromme|first38=Isabelle|last39=Karaarslan|first39=Isil Kilinc|last40=Ozdemir|first40=Fezal|last41=Tam|first41=Anthony|last42=Landi|first42=Christian|last43=Norton|first43=Peter|last44=Kaçar|first44=Nida|last45=Rudnicka|first45=Lidia|last46=Slowinska|first46=Monika|last47=Simionescu|first47=Olga|last48=Di Stefani|first48=Alessandro|last49=Coates|first49=Elliot|last50=Kreusch|first50=Juergen|title=Dermoscopic Evaluation of Nodular Melanoma|journal=JAMA Dermatology|volume=149|issue=6|year=2013|pages=699|issn=2168-6068|doi=10.1001/jamadermatol.2013.2466}}</ref>
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Polypoid nodule
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Dark color
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Lump
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * 6mm to > 1 cm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Trunk
| |
| * Head
| |
| * Neck
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Pigment network or pseudonetwork
| |
| * Aggregated brown or black globules
| |
| * Blue pigmentation within lesion
| |
| * Small dotted or comma vessels
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Cells proliferate downwards through the skin
| |
| | |
| * Dermal growth in isolation or in association with an epidermal component
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Two-thirds arise in normal skin, the rest in existing moles
| |
| * Rapidly enlarging
| |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Acral lentiginous melanoma]]'''<ref name="pmid19922528">{{cite journal| author=Phan A, Dalle S, Touzet S, Ronger-Savlé S, Balme B, Thomas L| title=Dermoscopic features of acral lentiginous melanoma in a large series of 110 cases in a white population. | journal=Br J Dermatol | year= 2010 | volume= 162 | issue= 4 | pages= 765-71 | pmid=19922528 | doi=10.1111/j.1365-2133.2009.09594.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19922528 }}</ref>
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Macule
| |
| * Patch
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Dark brown to black
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Raised areas
| |
| * Ulceration
| |
| * Bleeding
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Variable
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Palmar
| |
| * Plantar
| |
| * Subungual
| |
| * Mucosal surfaces
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Parallel-ridge pattern
| |
| * Irregular diffuse pigmentation
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Asymmetric proliferation of single melanocytes at dermoepidermal junction
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Most common among dark skinned individuals
| |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Amelanotic melanoma]]'''<ref name="pmid23197217">{{cite journal| author=Steglich RB, Meotti CD, Ferreira MS, Lovatto L, de Carvalho AV, de Castro CG| title=Dermoscopic clues in the diagnosis of amelanotic and hypomelanotic malignant melanoma. | journal=An Bras Dermatol | year= 2012 | volume= 87 | issue= 6 | pages= 920-3 | pmid=23197217 | doi= | pmc=3699915 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23197217 }}</ref>
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Patch
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Skin color
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Slightly elevated borders
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Around 6 mm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Sun-exposed areas
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * No melanin pigmentation
| |
| | |
| * Dotted vessels
| |
| * linear irregular vessels
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Lesions not pigmented since they don't produce melanin
| |
| *
| |
| |-
| |
| | colspan="2" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''[[Nevus|Common nevus]]<ref name="pmid20137743">{{cite journal| author=Witt C, Krengel S| title=Clinical and epidemiological aspects of subtypes of melanocytic nevi (Flat nevi, Miescher nevi, Unna nevi). | journal=Dermatol Online J | year= 2010 | volume= 16 | issue= 1 | pages= 1 | pmid=20137743 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20137743 }}</ref>'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Dome-shaped nodules
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Hypopigmented
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Smooth surface
| |
| * Terminal hairs often present
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * 1 cm to > 20 cm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Sun-exposed areas above the waist
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Comma-shaped or curved vessels
| |
| * Structureless light brown background
| |
| * Residual brown thick circles around the hair follicles
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Multinucleated melanocytes
| |
| * Melanocytes diffusely infiltrate dermis
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Also called Miescher nevus
| |
| |-
| |
| | colspan="2" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''[[Blue nevus]]'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Macules
| |
| * Papules
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Blue
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Smooth
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Variable
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Head and neck,
| |
| * Dorsal aspect of the distal extremities
| |
| * Sacral area
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Structureless blue pigmentation
| |
| * Structureless blue and white or blue and brown on some occasions
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Proliferation of dendritic, dermal, melanin-producing melanocytes
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Also called Mongolian spots
| |
| |-
| |
| | rowspan="2" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''Spitz nevus'''<ref name="pmid22082838">{{cite journal| author=Luo S, Sepehr A, Tsao H| title=Spitz nevi and other Spitzoid lesions part I. Background and diagnoses. | journal=J Am Acad Dermatol | year= 2011 | volume= 65 | issue= 6 | pages= 1073-84 | pmid=22082838 | doi=10.1016/j.jaad.2011.04.040 | pmc=3217183 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22082838 }}</ref>
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Nonpigmented Spitz nevus'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Nodules
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Pink
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Smooth
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * < 1 cm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Cheek
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Coiled vessels
| |
| * White network over a pink to reddish background
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * In children and adolescents
| |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Reed-like Spitz'''<ref name="pmid27222770">{{cite journal| author=Pedrosa AF, Lopes JM, Azevedo F, Mota A| title=Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation. | journal=Dermatol Pract Concept | year= 2016 | volume= 6 | issue= 2 | pages= 37-41 | pmid=27222770 | doi=10.5826/dpc.0602a07 | pmc=4866625 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27222770 }}</ref>
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Papule
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Heavily pigmented
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Smooth
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * < 1 cm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Head and neck
| |
| * Upper and lower extremities
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Structureless black to gray center
| |
| * Hypopigmented follicular openings
| |
| * Peripheral streaks
| |
| * Pseudopods
| |
| * Globules
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Enlarged spindle melanocytes with polyangular form
| |
| * "Ground glass" cytoplasm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Most commonly develops in children, adolescents, and young adults.
| |
| |-
| |
| | colspan="2" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''[[Solar lentigo]]'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Multiple spots
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Brown
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Smooth
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Around 5mm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Sun-exposed areas
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Faint pigmented fingerprint structures
| |
| * Structureless pattern
| |
| * Light brown pseudonetwork with well-defined borders and a "moth-eaten" edge
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * '''↑''' melanin deposition in keratinocytes
| |
| * '''↑''' linear arrangement of melanocytes at the dermoepidermal junction.
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Associated with UV exposure and skin aging
| |
| |-
| |
| | colspan="2" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''[[Sebaceous hyperplasia]]'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Papules
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Skin-colored to brownish
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Umbilicated
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * 2 - 6 mm
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Forehead
| |
| * Nose
| |
| * Cheeks
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Structureless yellow to whitish center surrounded by short linear "crown vessels"
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Usually in middle-aged or older patients
| |
| |-
| |
| | colspan="2" style="background: #C0C0C0; padding: 5px; text-align: center;" |'''Lichen planus-like keratosis'''
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Papule
| |
| * Plaque
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Gray to brown
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Prominent
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Variable
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Upper trunk
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Shows a coarse or fine, gray to blue, granular pigmentation
| |
| * Diffuse brownish gray granules
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Hypergranulosis
| |
| * Epidermal hyperplasia
| |
| * Superficial bandlike infiltrate
| |
| * Melanophages
| |
| | style="background: #F5F5F5; padding: 5px;" |
| |
| * Appearance depends on stage of evolution
| |
| |}
| |
| SCC in situ: Frequently, there is associated thickening of the epidermis (acanthosis), as well as hyperkeratosis and parakeratosis of the stratum corneum. In contrast to SCC in situ, actinic keratoses demonstrate only partial-thickness epidermal dysplasia.
| |
| | |
| ==References==
| |
| {{Reflist|2}}
| |