First degree AV block causes: Difference between revisions
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==Overview== | ==Overview== | ||
Common causes of [[first-degree AV block]] include [[ischemic heart disease]], [[congenital heart disease]], [[electrolyte]] abnormalities (particularly [[hypokalemia]] and [[hypomagnesemia]]), [[inflammation]], [[infections]] ([[endocarditis]], [[rheumatic fever]], [[Chagas disease]], [[Lyme disease]], [[diphtheria]]), [[drugs]] ([[antiarrhythmic ]] Ia, Ic, II, III, IV and [[digoxin]], [[β-blockers]], [[calcium channel blockers]] ), [[infiltrative diseases]] ([[sarcoidosis]]), [[collagen vascular diseases]] ([[SLE]], [[rheumatoid arthritis]], [[scleroderma]]), idiopathic degenerative diseases ([[Lenegre]] and [[Lev diseases]]) and [[neuromuscular disorders]] and increased [[vagal tone]] in younger [[patients]]. | |||
==Causes== | ==Causes== | ||
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*[[Hyperkalemia]] | *[[Hyperkalemia]] | ||
*[[Hyperthyroidism]] | *[[Hyperthyroidism]] | ||
*[[Hypothyroidism]] | |||
*[[vagus nerve|Increased vagal tone]] (e.g. [[sleep]], athletes) | *[[vagus nerve|Increased vagal tone]] (e.g. [[sleep]], athletes) | ||
*[[Ischemic heart disease]] | *[[Ischemic heart disease]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
|bgcolor="Beige"| [[Amiodarone]], [[beta-blockers]], [[digitalis]], [[calcium channel blockers]], [[cholinesterase inhibitor|cholinesterase inhibitors]], [[disopyramide]], [[dofetilide]], [[dolasetron]], [[donepezil]], [[eslicarbazepine acetate]], [[fesoterodine]], [[fingolimod]], [[flecainide]], [[ibutilide]], [[lacosamide]], [[magnesium]], [[paliperidone]], [[procainamide]], [[propafenone]], [[propoxyphene]], [[quinidine]], [[sotalol]], [[terodiline]] | |bgcolor="Beige"| [[Amiodarone]], [[beta-blockers]], [[digitalis]], [[calcium channel blockers]], [[cholinesterase inhibitor|cholinesterase inhibitors]], [[disopyramide]], [[dofetilide]], [[dolasetron]], [[donepezil]], [[eslicarbazepine acetate]], [[fesoterodine]], [[fingolimod]], [[flecainide]], [[ibutilide]], [[lacosamide]], [[magnesium]], [[paliperidone]], [[pramipexole]], [[procainamide]], [[propafenone]], [[propoxyphene]], [[quinidine]], [[sotalol]], [[terodiline]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Endocrine''' | | '''Endocrine''' | ||
|bgcolor="Beige"| [[Hyperthyroidism]], [[myxedema]], [[periodic paralysis|thyrotoxic periodic paralysis]] | |bgcolor="Beige"| [[Hyperthyroidism]], [[myxedema]], [[periodic paralysis|thyrotoxic periodic paralysis]], [[hypothyroidism]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Miscellaneous''' | | '''Miscellaneous''' | ||
|bgcolor="Beige"| [[Amyloidosis]], [[degenerative diseases]], [[vagus nerve|enhanced vagal tone]], [[PR interval|normal variants | |bgcolor="Beige"| [[Amyloidosis]], [[degenerative diseases]], [[vagus nerve|enhanced vagal tone]], [[PR interval|normal variants]] | ||
|- | |- | ||
|} | |} | ||
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{{col-begin|width=80%}} | {{col-begin|width=80%}} | ||
{{col-break|width=33%}} | {{col-break|width=33%}} | ||
*[[Acute | *[[Acute myocardial infarction]] | ||
*[[Acute rheumatic fever]] | *[[Acute rheumatic fever]] | ||
*[[Amyloidosis]] | *[[Amyloidosis]] | ||
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*[[Emery-Dreifuss muscular dystrophy]] | *[[Emery-Dreifuss muscular dystrophy]] | ||
*[[vagus nerve|Enhanced vagal tone in athletes]] | *[[vagus nerve|Enhanced vagal tone in athletes]] | ||
{{col-break|width=33%}} | |||
*[[Eslicarbazepine acetate]] | *[[Eslicarbazepine acetate]] | ||
*[[Fabry disease]] | *[[Fabry disease]] | ||
*[[Fesoterodine]] | *[[Fesoterodine]] | ||
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*[[Glycogenosis type 2b]] | *[[Glycogenosis type 2b]] | ||
*[[HCM]] | *[[HCM]] | ||
* [[Neuromuscular disease| | * [[Neuromuscular disease|Hereditary neuromuscular disease]] | ||
*[[Hodgkin lymphoma]] | *[[Hodgkin lymphoma]] | ||
*[[Hyperkalaemia]] | *[[Hyperkalaemia]] | ||
*[[Carotid sinus hypersensitivity|Hypersensitive carotid | *[[Carotid sinus hypersensitivity|Hypersensitive carotid sinus syndrome]] | ||
*[[Hyperthyroidism]] | *[[Hyperthyroidism]] | ||
*[[Hypokalaemia]] | *[[Hypokalaemia]] | ||
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*[[Myotonic dystrophy]] | *[[Myotonic dystrophy]] | ||
*[[Myxedema]] | *[[Myxedema]] | ||
{{col-break|width=33%}} | {{col-break|width=33%}} | ||
*[[Neonatal lupus erythematosus]] | |||
*[[prolonged PR interval|Normal variants of PR prolongation]] | *[[prolonged PR interval|Normal variants of PR prolongation]] | ||
*[[Paliperidone]] | *[[Paliperidone]] | ||
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*[[Sarcoidosis]] | *[[Sarcoidosis]] | ||
*[[SLE]] | *[[SLE]] | ||
*[[Systemic sclerosis]] | *[[Systemic sclerosis]] | ||
*[[Terodiline]] | *[[Terodiline]] | ||
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*[[Tolterodine]] | *[[Tolterodine]] | ||
*[[Transposition of the great vessels]] | *[[Transposition of the great vessels]] | ||
*[[vagus nerve|Vagal maneuvers]] | *[[vagus nerve|Vagal maneuvers]] | ||
*[[Valsalva maneuver]] | *[[Valsalva maneuver]] |
Latest revision as of 04:51, 22 July 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Raviteja Guddeti, M.B.B.S. [3]
Overview
Common causes of first-degree AV block include ischemic heart disease, congenital heart disease, electrolyte abnormalities (particularly hypokalemia and hypomagnesemia), inflammation, infections (endocarditis, rheumatic fever, Chagas disease, Lyme disease, diphtheria), drugs (antiarrhythmic Ia, Ic, II, III, IV and digoxin, β-blockers, calcium channel blockers ), infiltrative diseases (sarcoidosis), collagen vascular diseases (SLE, rheumatoid arthritis, scleroderma), idiopathic degenerative diseases (Lenegre and Lev diseases) and neuromuscular disorders and increased vagal tone in younger patients.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
- Hyperkalemia
- Hyperthyroidism
- Hypothyroidism
- Increased vagal tone (e.g. sleep, athletes)
- Ischemic heart disease
- Medications ( e.g. adenosine, amiodarone, beta-blockers, diltiazem, procainamide, verapamil)