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==Overview==


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Fluorodeoxyglucose positron emission tomography ([[FDG-PET]]) may be helpful in the [[diagnosis]] of [[Autoimmune lymphoproliferative syndrome]]([[ALPS]]) by distinguishing [[benign]] [[lymphadenopathy]] from [[malignant]] [[lymphadenopathy]].


==Other Imaging Findings==
[[PET]] [[scan]] can be an useful tool to minimize the number of [[lymph nodes]] to get biopsied based on degree of FDG acitivity in [[ALPS]] pateints with [[lymphoma]].FDG distribution in [[ALPS]] might be helpful to distiguish between [[ALPS]] [[adenopathy]] and [[ALPS]] associated [[lymphoma]]. <ref name="RaoOliveira2011">{{cite journal|last1=Rao|first1=V. Koneti|last2=Oliveira|first2=João Bosco|title=How I treat autoimmune lymphoproliferative syndrome|journal=Blood|volume=118|issue=22|year=2011|pages=5741–5751|issn=0006-4971|doi=10.1182/blood-2011-07-325217}}</ref>
[[File:PET ALPS.jpeg|center|thumb|520x520px|CT and FDG-PET scans featuring ALPS-FAS–associated lymphadenopathy and splenomegaly.<ref name="RaoOliveira2011" />]]
==References==
==References==
{{reflist|2}}
{{reflist|2}}


[[Category:Disease]]
[[Category:Hematology]]
[[Category:Hematology]]
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Latest revision as of 04:14, 3 August 2021

Autoimmune lymphoproliferative syndrome Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sharmi Biswas, M.B.B.S

Overview

Fluorodeoxyglucose positron emission tomography (FDG-PET) may be helpful in the diagnosis of Autoimmune lymphoproliferative syndrome(ALPS) by distinguishing benign lymphadenopathy from malignant lymphadenopathy.

Other Imaging Findings

PET scan can be an useful tool to minimize the number of lymph nodes to get biopsied based on degree of FDG acitivity in ALPS pateints with lymphoma.FDG distribution in ALPS might be helpful to distiguish between ALPS adenopathy and ALPS associated lymphoma. [1]

CT and FDG-PET scans featuring ALPS-FAS–associated lymphadenopathy and splenomegaly.[1]

References

  1. 1.0 1.1 Rao, V. Koneti; Oliveira, João Bosco (2011). "How I treat autoimmune lymphoproliferative syndrome". Blood. 118 (22): 5741–5751. doi:10.1182/blood-2011-07-325217. ISSN 0006-4971.