Syphilis: Difference between revisions

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'''For patient information on Syphilis, click [[{{PAGENAME}} (patient information)|here]]'''
__NOTOC__
{{About1|Treponema pallidum}}
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''


{{DiseaseDisorder infobox |
{{DiseaseDisorder infobox |
   Name          = Syphilis |
   Name          = Syphilis |
   Image          = Treponema pallidum.jpg |
   Image          = Treponema pallidum.jpg|
   Caption        = Image of spiral-shaped organisms responsible for causing syphilis |
   Caption        = Image of spiral-shaped organisms responsible for causing syphilis - Source: https://www.cdc.gov/ |
  ICD10          = {{ICD10|A|50||a|50}}-{{ICD10|A|53||a|50}} |
  ICD9          = {{ICD9|090}}-{{ICD9|097}} |
  ICDO          = |
  OMIM          = |
  DiseasesDB    = |
  MedlinePlus    = 001327 |
  eMedicineSubj  =|
  eMedicineTopic = |
  eMedicine_mult =
}}
}}
{{Syphilis}}
{{Syphilis}}
{{CMG}}; {{AOEIC}} {{LG}}
{{CMG}}; {{AOEIC}} {{LG}} {{AAA}} {{Kalpana Giri}}
 
{{SK}} Lues, Lues venerea, Luetic disease, The great imitator, Syph, Pox, Treponemal disease, Treponemal infection


==[[Syphilis overview|Overview]]==
==[[Syphilis overview|Overview]]==
==Classification==
[[Congenital syphilis]] | [[Syphilis pathophysiology#Pathophysiology: Acquired syphilis|Acquired syphilis]] | [[Neurosyphilis]] | [[Syphilitic aortitis]] | [[Tabes dorsalis]]


==[[Syphilis historical perspective|Historical Perspective]]==
==[[Syphilis historical perspective|Historical Perspective]]==


==Pathophysiology==
==[[Syphilis classification|Classification]]==
[[Syphilis pathophysiology#Primary syphilis|Primary syphilis]] | [[Syphilis pathophysiology#Secondary syphilis|Secondary syphilis]] | [[Syphilis pathophysiology#Latent syphilis|Latent syphilis]] | [[Syphilis pathophysiology#Tertiary syphilis|Tertiary syphilis]]
==[[Syphilis pathophysiology|Pathophysiology]]==
==[[Treponema pallidum|Causes]]==


==[[Syphilis epidemiology and demographics|Epidemiology & Demographics]]==
==[[Syphilis differential diagnosis|Differentiating Syphilis from other Diseases]]==
[[Syphilis epidemiology and demographics#Primary & Secondary Syphilis: United States|United States]] | [[Syphilis epidemiology and demographics#Age|Age]] | [[Syphilis epidemiology and demographics#Impact of Gender|Impact of Gender]] | [[Syphilis epidemiology and demographics#Race & Ethnicity|Race & Ethnicity]]
 
==[[Syphilis epidemiology and demographics|Epidemiology and Demographics]]==


==[[Syphilis risk factors|Risk Factors]]==
==[[Syphilis risk factors|Risk Factors]]==
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==[[Syphilis screening|Screening]]==
==[[Syphilis screening|Screening]]==


==[[Syphilis causes|Causes]]==
==[[Syphilis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
==[[Syphilis differential diagnosis|Differentiating Syphilis from other Diseases]]==
 
==[[Syphilis natural history|Natural History, Complications & Prognosis]]==


==Diagnosis==
==Diagnosis==
*'''History & symptoms:''' [[Syphilis history and symptoms#Primary syphilis|Primary syphilis]] | [[Syphilis history and symptoms#Secondary syphilis|Secondary syphilis]] | [[Syphilis history and symptoms#Latent syphilis|Latent syphilis]] | [[Syphilis history and symptoms#Tertiary syphilis|Tertiary syphilis]]
[[Syphilis history and symptoms|History and Symptoms]] | [[Syphilis physical examination|Physical Examination]] | [[Syphilis laboratory findings|Laboratory Findings]] | [[Syphilis chest x ray|Chest X Ray]] | [[Syphilis CT|CT]] | [[Syphilis MRI|MRI]] | [[Syphilis other imaging findings|Other Imaging Findings]] | [[Syphilis other diagnostic studies|Other Diagnostic Studies]]
 
*'''Physical examination:''' [[Syphilis physical examination#Primary syphilis: Chancre|Chancre]] | [[Syphilis physical examination#Secondary syphilis: Condylomata Lata|Condylomata lata]] | [[Syphilis physical examination#Tertiary syphilis: Gumma|Gumma]]
 
*'''Diagnostic tests:'''
:*'''Serology:''' [[Syphilis laboratory tests#Nontreponemal test|Non-treponemal test]] | [[Syphilis laboratory tests#Treponemal test|Treponemal test]] | [[Syphilis laboratory tests#Immunoassay|Immunoassay]]
 
:*[[Syphilis laboratory tests#Dark field microscopy|Dark field microscopy]]
 
:*[[Syphilis laboratory tests#CSF analysis|CSF analysis]]


==Treatment==
==Treatment==
*'''Pharmacotherapy:''' [[Syphilis medical therapy#Pharmacotherapy|Pencillin G therapy]] | [[Syphilis medical therapy#Pencillin allergy|Pencillin allergy]] | [[Syphilis medical therapy#Jarisch-Herxheimer reaction|Jarisch-Herxheimer reaction]]
[[Syphilis medical therapy|Medical Therapy]] | [[Syphilis management for primary and secondary stages|Primary and Secondary Syphilis]] | [[Syphilis management for latent stage|Latent Syphilis]] | [[Syphilis management for tertiary stage|Tertiary Syphilis]] | [[Syphilis management for neurosyphilis|Neurosyphilis]] | [[Syphilis management among HIV-infected persons|HIV-infected patients]] | [[Syphilis management during pregnancy|Pregnancy]] | [[Syphilis management of sexual partners|Management of sexual partners]] | [[Syphilis primary prevention|Primary Prevention]] | [[Syphilis secondary prevention|Secondary Prevention]] | [[Syphilis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Syphilis future or investigational therapies|Future or Investigational Therapies]]


*'''Management based on stages:''' [[Syphilis management for primary and secondary stages|Primary & Secondary syphilis]] | [[Syphilis management for latent stage|Latent syphilis]] | [[Syphilis management for tertiary stage|Tertiary syphilis]] | [[Neurosyphilis]]
==Case Studies==
 
[[Syphilis case study one|Case #1]]
*'''Specific population:''' [[Syphilis management among HIV-infected persons|HIV-infected patients]] | [[Syphilis management during pregnancy|Pregnancy]] | [[Syphilis management of sexual partners|Management of sexual partners]]
 
*'''Prevention:''' [[Syphilis primary prevention|Primary Prevention]] | [[Syphilis secondary prevention|Secondary Prevention]]


==Related Chapters==
==Related Chapters==


* [[Tuberculosis]] ([[TB]])
* [[Tuberculosis]] ([[TB]])
* [[Dyphtheria]]
* [[Diphtheria]]
* [[Side-chain theory]]
* [[Side-chain theory]]
* [[Treponema pallidum]]
* [[Treponema pallidum]]
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* [[Pandemic]]
* [[Pandemic]]


==Resources==
==External Links==
*[http://hivinsite.ucsf.edu/InSite?page=kb-05-01-04 UCSF HIV InSite Knowledge Base Chapter: Syphilis and HIV]
*[http://colman.net/eadv/index.html "A New Gold Standard For Syphilis?" Poster Presentation for European Academy of Dermatology and Venereology 2004 Spring Symposium]
*[http://www.stdhelp.org/about/syphilis.php Syphilis Pictures and Information]
*[http://medinfo.ufl.edu/other/histmed/clancy/ Kipkeepers, Pox and Gleet Vendors: A Rapid History of Syphilis]
*[http://www.poxhistory.com/ POX: Genius, Madness, and the Mysteries of Syphilis]
*[http://www.yourstdhelp.com/syphilis.html Syphilis Informational resource ]
*[http://www.pbs.org/wnet/secrets/case_syphilis/index.html Secrets of the Dead (PBS): The Syphilis Enigma]
*[http://www.cbc.ca/ideas/Aids Syphilis and AIDS: Lessons from history]
*[http://www.cdc.gov/std/Syphilis/STDFact-Syphilis.htm "Syphilis fact sheet" from the Center for Disease Control]
*[http://www.cdc.gov/std/Syphilis/STDFact-Syphilis.htm "Syphilis fact sheet" from the Center for Disease Control]
*[http://www.nobel.se/medicine/laureates/1927/wagner-jauregg-lecture.html The treatment of dementia paralytica by malaria inoculation (A Nobel Prize lecture, December 13, 1927)]
 
*[http://www.niaid.nih.gov/factsheets/stdsyph.htm National Institute of Allergy and Infectious Diseases Factsheet]
* [http://www.niaid.nih.gov/topics/syphilis/Pages/default.aspx National Institute of Allergy and Infectious Diseases Factsheet]
*[http://uk.reuters.com/article/oddlyEnoughNews/idUKN1443055520080115 New study blames Columbus for syphilis spread from Reuters  Jan 15, 2008]
 


{{Diseases of the skin and appendages by morphology}}
{{Diseases of the skin and appendages by morphology}}
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[[Category:Disease]]
[[Category:Disease]]
[[Category:Gynecology]]
[[Category:Gynecology]]
[[Category:Infectious disease]]
[[Category:Bacterial diseases]]
[[Category:Bacterial diseases]]
[[Category:Sexually transmitted diseases]]
[[Category:Sexually transmitted diseases]]
 
[[Category:Emergency mdicine]]
[[Category:Overview complete]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Urology]]
[[Category:Neurology]]

Latest revision as of 09:39, 28 September 2021

This page is about clinical aspects of the disease.  For microbiologic aspects of the causative organism(s), see Treponema pallidum.

For patient information click here

Template:DiseaseDisorder infobox

Sexually transmitted diseases Main Page

Syphilis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Syphilis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Primary and Secondary Syphilis
Latent Syphilis
Tertiary Syphilis
Neurosyphilis
HIV-Infected Patients
Pregnancy
Management of Sexual Partners

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Syphilis On the Web

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Directions to Hospitals Treating Syphilis

Risk calculators and risk factors for Syphilis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2] Aysha Aslam, M.B.B.S[3] Kalpana Giri, MBBS[4]

Synonyms and keywords: Lues, Lues venerea, Luetic disease, The great imitator, Syph, Pox, Treponemal disease, Treponemal infection

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Syphilis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | CT | MRI | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Primary and Secondary Syphilis | Latent Syphilis | Tertiary Syphilis | Neurosyphilis | HIV-infected patients | Pregnancy | Management of sexual partners | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Related Chapters

External Links


Template:STD/STI

Template:Spirochetal diseases

ar:زهري ast:Sífilis zh-min-nan:Mûi-to̍k bg:Сифилис ca:Sífilis cs:Syfilis da:Syfilis de:Syphilis eo:Sifiliso eu:Sifili hr:Sifilis ko:매독 io:Sifiliso id:Sifilis it:Sifilide he:עגבת la:Syphilis lt:Sifilis mk:Сифилис nl:Syfilis no:Syfilis qu:Wanthi unquy simple:Syphilis sk:Syfilis sl:Sifilis sr:Сифилис sh:Sifilis fi:Kuppa sv:Syfilis ta:சிபிலிசு th:ซิฟิลิส uk:Сифіліс


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