5-alpha-reductase deficiency classification: Difference between revisions
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== Overview == | == Overview == | ||
There are two [[isoforms]] of [[5-alpha reductase]] named type 1 and type 2. Type 1 [[5-alpha reductase]] is found mostly in the [[skin]] and [[liver]], which can get delivered to the [[prostate]] by [[systemic circulation]]. Type 2 is found only on prostatic [[tissue]] and is the most common form. So, [[5-alpha-reductase]] [[deficiency]] is known as [[5-alpha-reductase]] 2 [[deficiency]]. | |||
== Classification == | == Classification == | ||
There is no classification of [[5-alpha reductase]] deficiency as type 2 [[5-alpha reductase]] [[deficiency]] is the most common one.[<ref name="pmid20395661">{{cite journal| author=Walter KN, Kienzle FB, Frankenschmidt A, Hiort O, Wudy SA, van der Werf-Grohmann N | display-authors=etal| title=Difficulties in diagnosis and treatment of 5alpha-reductase type 2 deficiency in a newborn with 46,XY DSD. | journal=Horm Res Paediatr | year= 2010 | volume= 74 | issue= 1 | pages= 67-71 | pmid=20395661 | doi=10.1159/000313372 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20395661 }} </ref>] | |||
==References== | ==References== | ||
Latest revision as of 16:05, 23 December 2021
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Overview
There are two isoforms of 5-alpha reductase named type 1 and type 2. Type 1 5-alpha reductase is found mostly in the skin and liver, which can get delivered to the prostate by systemic circulation. Type 2 is found only on prostatic tissue and is the most common form. So, 5-alpha-reductase deficiency is known as 5-alpha-reductase 2 deficiency.
Classification
There is no classification of 5-alpha reductase deficiency as type 2 5-alpha reductase deficiency is the most common one.[[1]]
References
- ↑ Walter KN, Kienzle FB, Frankenschmidt A, Hiort O, Wudy SA, van der Werf-Grohmann N; et al. (2010). "Difficulties in diagnosis and treatment of 5alpha-reductase type 2 deficiency in a newborn with 46,XY DSD". Horm Res Paediatr. 74 (1): 67–71. doi:10.1159/000313372. PMID 20395661.