Biliary atresia other imaging findings: Difference between revisions
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{{Biliary atresia}} | {{Biliary atresia}} | ||
{{CMG}} '''Associate Editor | {{CMG}} '''Associate Editor-In-Chief''':{{skhan}} | ||
==Other Imaging Findings== | ==Other Imaging Findings== | ||
===== Nuclear medicine (hepatobiliary (HIDA) scan) ===== | =====Nuclear medicine (hepatobiliary (HIDA) scan)===== | ||
Cases of biliary atresia typically demonstrate relatively good hepatic uptake with no evidence of excretion into the bowel at 24 hours. Pretreatment with phenobarbital (5 mg/kg/day for 5 days) is done to stimulate hepatic enzymes in order to increase biliary secretion. This is helpful to minimize the possibility of a false-positive study due to pre-existing poor excretion. Radiotracers used are Tc-99m diosgenin (DISIDA) and mebrofenin (BRIDA) due to high hepatic extraction and short transit time. | Cases of biliary atresia typically demonstrate relatively good hepatic uptake with no evidence of excretion into the bowel at 24 hours. Pretreatment with phenobarbital (5 mg/kg/day for 5 days) is done to stimulate hepatic enzymes in order to increase biliary secretion. This is helpful to minimize the possibility of a false-positive study due to pre-existing poor excretion. Radiotracers used are Tc-99m diosgenin (DISIDA) and mebrofenin (BRIDA) due to high hepatic extraction and short transit time. | ||
Latest revision as of 18:38, 18 June 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief:Saud Khan M.D.
Other Imaging Findings
Nuclear medicine (hepatobiliary (HIDA) scan)
Cases of biliary atresia typically demonstrate relatively good hepatic uptake with no evidence of excretion into the bowel at 24 hours. Pretreatment with phenobarbital (5 mg/kg/day for 5 days) is done to stimulate hepatic enzymes in order to increase biliary secretion. This is helpful to minimize the possibility of a false-positive study due to pre-existing poor excretion. Radiotracers used are Tc-99m diosgenin (DISIDA) and mebrofenin (BRIDA) due to high hepatic extraction and short transit time.
Further testing include radioactive scans of the liver and a liver biopsy.