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=== Laboratory Findings ===
__NOTOC__
{{Sudden cardiac death}}
{{CMG}} {{AE}} {{Sara.Zand}} {{EdzelCo}}
 
==Overview==
[[Brain natriuretic peptide]] ([[BNP]]) or [[N-terminal pro-b-type-natriuretic peptide]] may have roles in the [[risk determination]] of [[patients]] for [[ventricular arrhythmia]] and [[sudden cardiac death]].
 
 
== Laboratory Findings ==
 
*An elevated concentration of [[brain natriuretic peptide]]([[BNP]]) or [[N-terminal pro-b-type-natriuretic peptide]] has been shown to have roles in the [[SCD]] risk determination of [[patients]] <ref name="ScottBarry2009">{{cite journal|last1=Scott|first1=Paul A.|last2=Barry|first2=James|last3=Roberts|first3=Paul R.|last4=Morgan|first4=John M.|title=Brain natriuretic peptide for the prediction of sudden cardiac death and ventricular arrhythmias: a meta-analysis|journal=European Journal of Heart Failure|volume=11|issue=10|year=2009|pages=958–966|issn=13889842|doi=10.1093/eurjhf/hfp123}}</ref> <ref name="pmid21044699">{{cite journal| author=Patton KK, Sotoodehnia N, DeFilippi C, Siscovick DS, Gottdiener JS, Kronmal RA| title=N-terminal pro-B-type natriuretic peptide is associated with sudden cardiac death risk: the Cardiovascular Health Study. | journal=Heart Rhythm | year= 2011 | volume= 8 | issue= 2 | pages= 228-33 | pmid=21044699 | doi=10.1016/j.hrthm.2010.10.038 | pmc=3826546 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21044699  }} </ref> <ref name="pmid32700639">{{cite journal| author=Everett BM, Moorthy MV, Tikkanen JT, Cook NR, Albert CM| title=Markers of Myocardial Stress, Myocardial Injury, and Subclinical Inflammation and the Risk of Sudden Death. | journal=Circulation | year= 2020 | volume= 142 | issue= 12 | pages= 1148-1158 | pmid=32700639 | doi=10.1161/CIRCULATIONAHA.120.046947 | pmc=7995996 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32700639  }} </ref> <ref name="pmid12021226">{{cite journal| author=Berger R, Huelsman M, Strecker K, Bojic A, Moser P, Stanek B | display-authors=etal| title=B-type natriuretic peptide predicts sudden death in patients with chronic heart failure. | journal=Circulation | year= 2002 | volume= 105 | issue= 20 | pages= 2392-7 | pmid=12021226 | doi=10.1161/01.cir.0000016642.15031.34 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12021226  }} </ref>.
*However, there is still a lack of sufficient evidence on the use of [[BNP]] as a method in the selection for the need of an [[implantable cardioverter defibrillators]] ([[ICD]]) <ref name="pmid19789399">{{cite journal| author=Scott PA, Barry J, Roberts PR, Morgan JM| title=Brain natriuretic peptide for the prediction of sudden cardiac death and ventricular arrhythmias: a meta-analysis. | journal=Eur J Heart Fail | year= 2009 | volume= 11 | issue= 10 | pages= 958-66 | pmid=19789399 | doi=10.1093/eurjhf/hfp123 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19789399  }} </ref> <ref name="pmid24952693">{{cite journal| author=Ahmad T, Fiuzat M, Neely B, Neely ML, Pencina MJ, Kraus WE | display-authors=etal| title=Biomarkers of myocardial stress and fibrosis as predictors of mode of death in patients with chronic heart failure. | journal=JACC Heart Fail | year= 2014 | volume= 2 | issue= 3 | pages= 260-8 | pmid=24952693 | doi=10.1016/j.jchf.2013.12.004 | pmc=4224312 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24952693  }} </ref>.
 
 


*An elevated concentration of  [[brain natriuretic peptide]] ([[BNP]]) predicts has been shown as the predictor of [[ventricular arrhythmia]] and [[sudden cardiac death]].<ref name="ScottBarry2009">{{cite journal|last1=Scott|first1=Paul A.|last2=Barry|first2=James|last3=Roberts|first3=Paul R.|last4=Morgan|first4=John M.|title=Brain natriuretic peptide for the prediction of sudden cardiac death and ventricular arrhythmias: a meta-analysis|journal=European Journal of Heart Failure|volume=11|issue=10|year=2009|pages=958–966|issn=13889842|doi=10.1093/eurjhf/hfp123}}</ref>
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Latest revision as of 21:14, 19 July 2023

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Zand, M.D.[2] Edzel Lorraine Co, DMD, MD[3]

Overview

Brain natriuretic peptide (BNP) or N-terminal pro-b-type-natriuretic peptide may have roles in the risk determination of patients for ventricular arrhythmia and sudden cardiac death.


Laboratory Findings


References

  1. Scott, Paul A.; Barry, James; Roberts, Paul R.; Morgan, John M. (2009). "Brain natriuretic peptide for the prediction of sudden cardiac death and ventricular arrhythmias: a meta-analysis". European Journal of Heart Failure. 11 (10): 958–966. doi:10.1093/eurjhf/hfp123. ISSN 1388-9842.
  2. Patton KK, Sotoodehnia N, DeFilippi C, Siscovick DS, Gottdiener JS, Kronmal RA (2011). "N-terminal pro-B-type natriuretic peptide is associated with sudden cardiac death risk: the Cardiovascular Health Study". Heart Rhythm. 8 (2): 228–33. doi:10.1016/j.hrthm.2010.10.038. PMC 3826546. PMID 21044699.
  3. Everett BM, Moorthy MV, Tikkanen JT, Cook NR, Albert CM (2020). "Markers of Myocardial Stress, Myocardial Injury, and Subclinical Inflammation and the Risk of Sudden Death". Circulation. 142 (12): 1148–1158. doi:10.1161/CIRCULATIONAHA.120.046947. PMC 7995996 Check |pmc= value (help). PMID 32700639 Check |pmid= value (help).
  4. Berger R, Huelsman M, Strecker K, Bojic A, Moser P, Stanek B; et al. (2002). "B-type natriuretic peptide predicts sudden death in patients with chronic heart failure". Circulation. 105 (20): 2392–7. doi:10.1161/01.cir.0000016642.15031.34. PMID 12021226.
  5. Scott PA, Barry J, Roberts PR, Morgan JM (2009). "Brain natriuretic peptide for the prediction of sudden cardiac death and ventricular arrhythmias: a meta-analysis". Eur J Heart Fail. 11 (10): 958–66. doi:10.1093/eurjhf/hfp123. PMID 19789399.
  6. Ahmad T, Fiuzat M, Neely B, Neely ML, Pencina MJ, Kraus WE; et al. (2014). "Biomarkers of myocardial stress and fibrosis as predictors of mode of death in patients with chronic heart failure". JACC Heart Fail. 2 (3): 260–8. doi:10.1016/j.jchf.2013.12.004. PMC 4224312. PMID 24952693.

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