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{{CMG}}
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==Side effects==
==List of side effects==
<font size="4">[[Prednisone side effects#Fluid and Electrolyte Disturbances|Fluid and Electrolyte Disturbances]]</font>
<font size="4">[[Prednisone side effects#Fluid and Electrolyte Disturbances|Fluid and Electrolyte Disturbances]]</font>
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*Potassium loss
*Potassium loss
*Hypokalemic alkalosis
*Hypokalemic alkalosis
*Hypertension ''[[Prednisone side effects#Side effects|Return to top]]''
*Hypertension ''[[Prednisone side effects#List of side effects|Return to top]]''
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=== Musculoskeletal===
=== Musculoskeletal===
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*Osteoporosis
*Osteoporosis
*Vertebral compression fractures
*Vertebral compression fractures
*Aseptic necrosis of femoral and humeral heads  ''[[Prednisone side effects#Side effects|Return to top]]''
*Aseptic necrosis of femoral and humeral heads  ''[[Prednisone side effects#List of side effects|Return to top]]''
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===Gastrointestinal===
===Gastrointestinal===
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*Pancreatitis
*Pancreatitis
*Abdominal distention  
*Abdominal distention  
*Ulcerative esophagitis ''[[Prednisone side effects#Side effects|Return to top]]''
*Ulcerative esophagitis ''[[Prednisone side effects#List of side effects|Return to top]]''
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===Dermatologic===
===Dermatologic===
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*Facial erythema
*Facial erythema
*Increased sweating
*Increased sweating
*May suppress reactions to skin tests ''[[Prednisone side effects#Side effects|Return to top]]''
*May suppress reactions to skin tests ''[[Prednisone side effects#List of side effects|Return to top]]''
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===Neurological===
===Neurological===
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*Increased intracranial pressure with papilledema (pseudo-tumor cerebri) usually after treatment
*Increased intracranial pressure with papilledema (pseudo-tumor cerebri) usually after treatment
*Vertigo
*Vertigo
*Headache  ''[[Prednisone side effects#Side effects|Return to top]]''
*Headache  ''[[Prednisone side effects#List of side effects|Return to top]]''
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===Endocrine===
===Endocrine===
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*Decreased carbohydrate tolerance
*Decreased carbohydrate tolerance
*Manifestations of latent diabetes mellitus
*Manifestations of latent diabetes mellitus
*Increased requirements for insulin or oral hypoglycemic agents in diabetics ''[[Prednisone side effects#Side effects|Return to top]]''
*Increased requirements for insulin or oral hypoglycemic agents in diabetics ''[[Prednisone side effects#List of side effects|Return to top]]''
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===Ophthalmic===
===Ophthalmic===
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*Increased intraocular pressure
*Increased intraocular pressure
*Glaucoma
*Glaucoma
*Exophthalmos  ''[[Prednisone side effects#Side effects|Return to top]]''
*Exophthalmos  ''[[Prednisone side effects#List of side effects|Return to top]]''
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===Metabolic===
===Metabolic===
Negative nitrogen balance due to protein catabolism  ''[[Prednisone side effects#Side effects|Return to top]]''
Negative nitrogen balance due to protein catabolism  ''[[Prednisone side effects#List of side effects|Return to top]]''
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{{FDA}}
{{FDA}}

Latest revision as of 13:08, 19 December 2011

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

List of side effects

Fluid and Electrolyte Disturbances

Musculoskeletal

Gastrointestinal

Dermatologic

Neurological

Endocrine

Ophthalmic

Metabolic



Fluid and Electrolyte Disturbances

  • Sodium retention
  • Fluid retention
  • Congestive heart failure in susceptible patients
  • Potassium loss
  • Hypokalemic alkalosis
  • Hypertension Return to top


Musculoskeletal

  • Muscle weakness
  • Steroid myopathy
  • Loss of muscle mass
  • Osteoporosis
  • Vertebral compression fractures
  • Aseptic necrosis of femoral and humeral heads Return to top


Gastrointestinal

  • Peptic ulcer with possible perforation and hemorrhage
  • Pancreatitis
  • Abdominal distention
  • Ulcerative esophagitis Return to top


Dermatologic

  • Impaired wound healing
  • Thin fragile skin
  • Petechiae and ecchymoses
  • Facial erythema
  • Increased sweating
  • May suppress reactions to skin tests Return to top


Neurological

  • Convulsions
  • Increased intracranial pressure with papilledema (pseudo-tumor cerebri) usually after treatment
  • Vertigo
  • Headache Return to top


Endocrine

  • Menstrual irregularities
  • Development of cushingoid state
  • Suppression of growth in children
  • Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness
  • Decreased carbohydrate tolerance
  • Manifestations of latent diabetes mellitus
  • Increased requirements for insulin or oral hypoglycemic agents in diabetics Return to top


Ophthalmic

  • Posterior subcapsular cataracts
  • Increased intraocular pressure
  • Glaucoma
  • Exophthalmos Return to top


Metabolic

Negative nitrogen balance due to protein catabolism Return to top




Adapted from the FDA Package Insert.