Pulmonary artery sarcoma: Difference between revisions
(4 intermediate revisions by the same user not shown) | |||
Line 22: | Line 22: | ||
*Absence of a [[procoagulant]] state | *Absence of a [[procoagulant]] state | ||
*Lack of history for [[deep vein thrombosis]] | *Lack of history for [[deep vein thrombosis]] | ||
==Natural History, Complications, and Prognosis== | |||
The prognosis for a pulmonary artery sarcoma is very poor. The life expectancy is typically reported in weeks instead of months or years.<ref name="pmid19231448">{{cite journal |author=Blackmon SH, Rice DC, Correa AM, Mehran R, Putnam JB, Smythe WR, Walkes JC, Walsh GL, Moran C, Singh H, Vaporciyan AA, Reardon M |title=Management of primary pulmonary artery sarcomas |journal=[[The Annals of Thoracic Surgery]] |volume=87 |issue=3 |pages=977–84 |year=2009 |month=March |pmid=19231448 |doi=10.1016/j.athoracsur.2008.08.018 |url=http://linkinghub.elsevier.com/retrieve/pii/S0003-4975(08)01671-8 |accessdate=2012-08-03}}</ref> | |||
==Diagnosis== | ==Diagnosis== | ||
Line 31: | Line 35: | ||
*[[Chest pain]] | *[[Chest pain]] | ||
*[[Cough]] | *[[Cough]] | ||
===Laboratory Findings=== | |||
====CT==== | |||
Many different imaging studies can be used to evaluate a pulmonary artery sarcoma, but the standard test is the CT scan. | |||
==Treatment== | |||
===Pharmacotherapy=== | |||
====Chronic Pharmacotherapies==== | |||
Typically in cases of cancer, [[chemotherapy]] is the preferred treatment method. In the case of a pulmonary artery sarcoma, treatment with chemotherapy is not ideal. There is not currently a preferred treatment regimen.<ref name="pmid19231448">{{cite journal |author=Blackmon SH, Rice DC, Correa AM, Mehran R, Putnam JB, Smythe WR, Walkes JC, Walsh GL, Moran C, Singh H, Vaporciyan AA, Reardon M |title=Management of primary pulmonary artery sarcomas |journal=[[The Annals of Thoracic Surgery]] |volume=87 |issue=3 |pages=977–84 |year=2009 |month=March |pmid=19231448 |doi=10.1016/j.athoracsur.2008.08.018 |url=http://linkinghub.elsevier.com/retrieve/pii/S0003-4975(08)01671-8 |accessdate=2012-08-03}}</ref> | |||
===Surgery and Device Based Therapy=== | |||
Many of the interventional treatments involve extensive surgical techniques. Some of these techniques include: | |||
*[[Palliative stenting]] | |||
*[[Pneumonectomy]] | |||
*[[Debulking]] | |||
*[[Endarterectomy]] | |||
*[[Excision]] | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Latest revision as of 15:08, 3 August 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pulmonary artery sarcomas are rare cancerous tumors in the pulmonary artery.
Historical Perspective
The first case that was published occurred in 1923 by M. Mandelstamm.[1] Since this point, only about 250 cases have been reported.
Differentiating pulmonary artery sarcoma from other Diseases
Since the symptoms of a pulmonary artery sarcoma often mimic the symptoms of a pulmonary embolism, steps need to be taken to differentiate the diseases. Some of the clinical data that can help in differentiating the two from each other are as follows:[1]
- Fever
- Elevated erythrocyte sedimentation rate
- Anemia
- Weight loss
- Absence of a procoagulant state
- Lack of history for deep vein thrombosis
Natural History, Complications, and Prognosis
The prognosis for a pulmonary artery sarcoma is very poor. The life expectancy is typically reported in weeks instead of months or years.[1]
Diagnosis
Symptoms
Laboratory Findings
CT
Many different imaging studies can be used to evaluate a pulmonary artery sarcoma, but the standard test is the CT scan.
Treatment
Pharmacotherapy
Chronic Pharmacotherapies
Typically in cases of cancer, chemotherapy is the preferred treatment method. In the case of a pulmonary artery sarcoma, treatment with chemotherapy is not ideal. There is not currently a preferred treatment regimen.[1]
Surgery and Device Based Therapy
Many of the interventional treatments involve extensive surgical techniques. Some of these techniques include:
References
- ↑ 1.0 1.1 1.2 1.3 Blackmon SH, Rice DC, Correa AM, Mehran R, Putnam JB, Smythe WR, Walkes JC, Walsh GL, Moran C, Singh H, Vaporciyan AA, Reardon M (2009). "Management of primary pulmonary artery sarcomas". The Annals of Thoracic Surgery. 87 (3): 977–84. doi:10.1016/j.athoracsur.2008.08.018. PMID 19231448. Retrieved 2012-08-03. Unknown parameter
|month=
ignored (help)