Antianalgesia: Difference between revisions
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'''Antianalgesia''' is the ability of some endogenous chemicals (notably [[cholecystokinin]] and [[neuropeptide Y]]) to counter the effects of exogenous [[analgesics]] (such as [[morphine]]) or endogenous pain inhibiting [[neurotransmitters]]/modulators, such as the endogenous opioids.<ref>{{cite journal | first = EP | last = Wiertelak | coauthors = Maier, SF and Watkins, LR | year = 1992 | month = 8 May | title = Cholecystokinin antianalgesia: safety cues abolish morphine analgesia | journal = Science | volume = 256 | issue = 5058 | pages = 830 - 833 | id = {{doi|10.1126/science.1589765}} | url = http://www.sciencemag.org/cgi/content/abstract/256/5058/830 | accessdate = 2007-02-12}}</ref> A learned form can be established using methods similar to the learning principle of conditioned inhibition, and has been demonstrated in rats. | '''Antianalgesia''' is the ability of some endogenous chemicals (notably [[cholecystokinin]] and [[neuropeptide Y]]) to counter the effects of exogenous [[analgesics]] (such as [[morphine]]) or endogenous pain inhibiting [[neurotransmitters]]/modulators, such as the endogenous opioids.<ref>{{cite journal | first = EP | last = Wiertelak | coauthors = Maier, SF and Watkins, LR | year = 1992 | month = 8 May | title = Cholecystokinin antianalgesia: safety cues abolish morphine analgesia | journal = Science | volume = 256 | issue = 5058 | pages = 830 - 833 | id = {{doi|10.1126/science.1589765}} | url = http://www.sciencemag.org/cgi/content/abstract/256/5058/830 | accessdate = 2007-02-12}}</ref> A learned form can be established using methods similar to the learning principle of conditioned inhibition, and has been demonstrated in rats. | ||
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Latest revision as of 22:18, 8 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Antianalgesia is the ability of some endogenous chemicals (notably cholecystokinin and neuropeptide Y) to counter the effects of exogenous analgesics (such as morphine) or endogenous pain inhibiting neurotransmitters/modulators, such as the endogenous opioids.[1] A learned form can be established using methods similar to the learning principle of conditioned inhibition, and has been demonstrated in rats.
References
- ↑ Wiertelak, EP (1992). "Cholecystokinin antianalgesia: safety cues abolish morphine analgesia". Science. 256 (5058): 830–833. doi:10.1126/science.1589765. Retrieved 2007-02-12. Unknown parameter
|month=ignored (help); Unknown parameter|coauthors=ignored (help)